SpectraCell Blog

Discrepancy or Deficiency? Vitamin D

Posted by SpectraCell Laboratories, Inc. on Fri, Nov 19, 2010 @ 04:04 PM

Vitamin DIt seems that there is a consistent issue with variances of serum and functional measurements of vitamin D.

In short, serum determinations give a static quantitative measurement while functional intracellular assays reflect the long term status of Vitamin D levels.

The results of the serum and functional tests may or may not be in agreement, but this apparently conflicting information is still useful to physicians and patients. If a patient has a low serum level of vitamin D, yet the functional test is normal, these results suggest a short term deficiency of vitamin D and the patient should be repleted. If the serum test is normal, yet the functional test is deficient, the cell may need more vitamin D for optimal function and the patient should be repleted. Therefore both tests are useful in assessing the vitamin D status of patients.

The same principal described for vitamin D may occur with any analyte for which we are reporting functional test results.

What are your thoughts on the difference between functional testing and serum testing?

Topics: micronutrients, micronutrient testing, Vitamin D, deficiencies, intracellular