Cysteine - Oral supplementation with cysteine, the precursor to glutathione, has therapeutic potential for sleep apnea. Snore time and duration were significantly reduced for patients treated with N-acetyl cysteine compared to untreated sleep apnea patients.
Antioxidant Status - It is well documented that sleep apnea patients have both reduced antioxidant capacity and higher levels of oxidative stress than controls.
Vitamin C - Improves endothelial function (blood vessel health) in sleep apnea patients to levels seen in people without sleep apnea.
Vitamin E - Mitigates the oxidative stress seen in sleep apnea patients; Works synergistically with Vitamin C.
Vitamin A - Sleep apnea patients have low retinol (vitamin A); Retinol suppresses the growth of vascular smooth muscle, a process that causes blood vessels to clog, linking low vitamin A levels to the cardiovascular complications seen in sleep apnea patients.
Vitamin D - People with sleep apnea have a high prevalence of vitamin D deficiency; The worse the apnea, the more severe the deficiency; Evidence suggests low vitamin D worsens sleep apnea's negative effect on heart disease risk.
Selenium - In one case report, selenium supplementation completely stopped snoring caused by non-obesity sleep apnea; Selenium's role as a potent antioxidant may reduce the oxidative stress seen in sleep apnea patients.
Copper - Considered a strong predictor of oxidative stress in sleep apnea patients; Copper's role as a key cofactor in the powerful antioxidant superoxide dismutase (SOD) explains this; SOD is very low in apnea patients.
Minerals - The trace minerals zinc, copper; magnesium, manganese and selenium are critical cofactors for the major antioxidant enzymes, which are important in repairing cellular damage caused by hypoxia (lack of oxygen) in sleep apnea.
Glutathione - Low levels linked to sleep apnea; This powerful antioxidant helps repair liver damage caused by sleep apnea.