SpectraCell Blog

SpectraCell Case Study - Female with Multiple Conditions!

Posted by SpectraCell Laboratories, Inc. on Thu, Jul 18, 2013 @ 03:03 PM

In 2006, a 45 year old female with complaints of multiple conditions including hypertension,case study MNT dyslipidemias, insomnia, athralgias, mitral valve prolapse, GERD and HSVI, tried SpectraCell testing only to reveal  deficiencies in key vitamins and minerals. 

This patient experienced malaise fatigue (x3-4years), joint pain, thin nails, sleep onset insomnia and hot flashes.  She had been taking Micardis (40/12.5), Ibuprofen (800mg as needed), vitamin D3 (1,000IU), Lasix (20mg as needed) and Valtrex (500mg daily) for prophylaxis.  Spectracell's micronutrient test revealed deficiencies in vitamin A, vitamin D, vitamin E, zinc, magnesium, CoQ10 and antioxidants.  Based upon her deficiencies, she was administered the following treatment protocol:

  • 1,000 IU/day of vitamin D3
  • 5,000 IU/day of vitamin A
  • 25 mg/day of zinc
  • 300-400 mg/day of magnesium
  • 100 mg/day of CoQ10
  • 400 IU d-alpha tocopherol & antioxidants of vitamin E
  • 100 MCG/day of selenium 

Clinical Outcome:
Fatigue/tiredness improved significantly - she can now do exercises at the gym.  Her nails became stronger and don't break easily.  Joint pains have decreased significantly.  Blood pressure is more controlled.  Insomnia improved and the hot flashes minimized.  Increased focus and concentration at work.  Improved memory compared to before.  Overall quality of life improved significantly.  She can now pursue her hobby (gardening) with enthusiasm and interest.

Follow up Nutritional Testing:
The previous deficiencies were corrected.  New deficiencies were far fewer than before - vitamin B12, selenium and antioxidants.

Conclusion:
She stated she had tried treatments in the past before SpectraCell's micronutrient testing, but nothing had helped her.  Following the testing and then replenishing with supplements in the appropriate dosages, has brought significant positive changes in her day to day functions.

SpectraCell Laboratories is combining the Micronutrient Testing and MTHFR Genotyping as a special package promotion.  To find out more CLICK HERE!




Topics: micronutrients, micronutrient testing, Coenzyme Q10, Autoimmunity, autoimmune diseases, zinc, Vitamin D, Magnesium, Vitamin A, Selenium, B Vitamins, Antioxidants, Minerals, hypertension, Aging, athralgias, dyslipidemias, HSVI, GERD, insomnia, mitral valve prolapse

Why Test YOUR Micronutrient Levels & MTHFR?

Posted by SpectraCell Laboratories, Inc. on Wed, Jul 10, 2013 @ 01:49 PM

New Grid 2013


Why is an MTHFR test important?

Determining your MTHFR genotype gives you valuable information about your body's ability to methylate.  Methylation is a crucial part of cell processes and reduced function has been linked to numerous medical conditions including neurological and cardiovascular disorders, mental dysfunctions and diabetes.  The old paradigm that we are simply at the mercy of our genes is now challenged by a new age of truly individualized healthcare.  Get vital knowledge for your personalized healthcare solutions today.

What role does nutrition play in this function?

Nutrition plays a substantial role in methylation pathways, and SpectraCell's Micronutrient testing can give you an accurate stats of 33 vitamins, minerals and amino acids.  You may be able to compensate for your body's inability to methylate efficiently through targeted repletion, and micronutrient testing will provide assessment of nutritional deficiencies.  The test also allows you to identify deficiencies in other micronutrients that can be contributing toward the development and/or progression of chronic disease and keep you from feeling your best.

SpectraCell Laboratories is combining the Micronutrient Testing and MTHFR Genotyping as a special package promotion.  To find out more CLICK HERE!

Topics: SpectraCell, micronutrients, micronutrient testing, Autoimmunity, cancer cells, autoimmune diseases, telomere length, Telomere testing, telomerase, B Vitamins, Antioxidants, Cardiovascular Health, MTHFR Genotyping, Genotyping, Heart Disease, vitamin, nutrition testing, supplements, Chronic Disease, diabetes, immune system, expecting mothers, early pregnancy, E-zinc, breast cancer, telomere, Elderly, Dr. Ron Grabowski, Minerals, micronutrient test, Nutritional Deficiency, Cancer Prevention, Heart Health, Gastrointestinal Tract, Hormones, telomere and cancer, Spectrox, Energy, Methylation, Estrogen, Immunidex, eczema and nutrition, Alzheimers, Free Radicals, Genetics, Dr. Eva Cwynar, Women's Health

Micronutrients Can Help!

Posted by SpectraCell Laboratories, Inc. on Wed, May 22, 2013 @ 02:19 PM

Topics discussed in this issue...                                            

  • Research suggests nutrient depletions from commonly prescribed drugs are actually the cause of many side effects
  • Study sheds light on how oleic acid improves immunity
  • Serine for arthritis?
  • CoQ10 shows potential as an anti-depressant
  • When it comes to colorectal cancer risk, cysteine = good, homocysteine = bad

Research suggests nutrient depletions fromprescribed drugs commonly prescribed drugs are actually the cause of many side effects - A recently published review details the enzymatic pathways that various drugs interrupt and how certain drugs deplete very specific nutrients. Nutrient depletions are implicated as a cause of common side effects and even non-compliance. 

 

oleic acidStudy sheds light on how oleic acid improves immunity - By affecting compounds released during an immune response, oleic acid quells inflammation and improves overall immunity. Specifically, oleic acid, abundant in olive oil, inhibits the production of several pro-inflammatory substances, such as Interleukin 2 (IL-2), natural killer cells (NK), interferon-gamma (INF-γ) and vascular cell adhesion molecules (VCAM). Oleic acid also reduces the amount of arachidonic acid (AA) present in cells, which in turn minimizes pro-inflammatory cytokine production.


arthritisSerine for arthritis? - Human cells from rheumatoid arthritis patients were exposed to phosphatidylserine and then evaluated for levels of inflammation.  The phosphatidylserine significantly lowered inflammation levels in vitro.  The same researchers tested phosphatidylserine’s effect on arthritic pain in an animal model and found that phosphatidylserine, which has well-established roles in neurotransmitter function, also decreased arthritic and pain symptoms.

 

CoQ10

CoQ10 shows potential as an anti-depressant - Four different doses of CoQ10 were administered for three weeks in an animal study on depression caused by chronic stress.  Depressive behaviors evaluated as were physiological markers of oxidative stress in the brain. Depressive symptoms were decreased and there was a dose-dependent reduction in damaging chemicals in the brain that are linked with depression. The authors concluded “CoQ10 may have a potential therapeutic value for the management of depressive disorders.”


cysteineWhen it comes to colorectal cancer risk, cysteine = good, homocysteine = bad. - In this clinical trial, levels of the toxic amino acid homocysteine and levels of the beneficial antioxidant cysteine were measured in over 900 women with colorectal cancer and compared to a similar group of over 900 women without cancer.   Those with the highest homocysteine (over 9.85 μmol/L) were 1.5 times more likely to have colorectal cancer than those with the lowest levels (>6.74 μmol/L).  Conversely, women with the highest levels of cysteine in the blood had a much lower risk of colorectal cancer than those with the lowest levels of cysteine.

 
For the complete article with journal abstracts,
full text and flyers click here

Topics: SpectraCell, serine, micronutrients, micronutrient testing, Homocysteine, Coenzyme Q10, Oleic Acid, Arthritis, Alpha-Lipoic Acid, Asparagine, Cysteine, Antidepressants, Cancer, Autoimmunity, cancer cells, autoimmune diseases

Theories, Research and Treatment with Vitamins and Antioxidants

Posted by SpectraCell Laboratories, Inc. on Thu, Mar 07, 2013 @ 09:31 AM

New theory on how vitamins work gains attention

A group of researchers in Europe proposed a new theory on how vitamins work in the body,vitamins displacing the former accepted view that vitamin molecules work directly on cells in the body. Their research, which used radiation and electron pulse technology, led them to conclude that antioxidant vitamins emit dissolved electrons that quench free radicals. They concluded that the well-known vitamin effects are attributed to “vitamin free radicals rather than the vitamin molecules per se, as generally accepted.”(Nutrition, January 2013)

Link to Abstract Vitamin-induced intracellular electrons are the mechanism for their well-known beneficial effects: A review.

Treatment resistant depression responds to folate therapy

Two randomized, double-blind trials were conducted in which depression, treatmentdepression patients who had a partial or no response to a SSRI (selective serotonin reuptake inhibitors) were given l-methylfolate for 60 days. In the first trial, the dosage of folate was 7.5mg/day for 30 days, then 15mg/day for 30 days. In the second trial, the dosage of folate was 15mg/day for 60 days. Patients in the second trial showed significantly greater efficacy of SSRI drugs (lower depression scores and significantly decreased symptom severity) compared to the first trial (where the dosage of folate was lower) and compared to placebo. (American Journal of Psychiatry, December 2012)

LINK to ABSTRACT  (L)-methylfolate as adjunctive therapy for SSRI-resistant major depression: results of two randomized, double-blind, parallel-sequential trial.
LINK to FLYER on NUTRIENT INTERACTIONS IN DEPRESSION

Antioxidant therapy benefits both anxiety and depression

Blood levels of the antioxidant (specifically, vitamins A, C and E) were measured in eighty patients ofantioxidant a psychiatric hospital that were diagnosed with stress-induced generalized anxiety disorder and depression. Supplements of each vitamin were given for six weeks and blood levels of each vitamin were measured again. After six weeks, blood levels of vitamin A and C had increased and there was a “significant reduction in anxiety and depression scores of patients.”(Indian Journal of Psychiatry, July2012)

LINK to ABSTRACT Role of antioxidants in generalised anxiety disorder and depression. 
LINK to FREE FULL TEXT
LINK to FLYER on NUTRIENT INTERACTIONS IN ANXIETY
LINK to FLYER on NUTRIENT INTERACTIONS IN DEPRESSION

Is B12 the magic bullet for hepatitis?

This paper concludes that B12 is particularly beneficial for hepatitis C viral therapy. Specifically, adding Vitamin B12vitamin B12 (5mg given intramuscularly every 4 weeks) to the conventional therapy of pegylated interferon plus ribavirin improved treatment response after 3 months. This confirms earlier research that shows vitamin B12 ca inhibit the hepatitis C virus in vitro.(Expert Review of Anti-Infective Therapy, November 2012)

LINK to ABSTRACT Vitamins? The magic bullet against hepatitis C.
LINK to FREE FULL TEXT

Vitamin D amplifies progesterone's neuroprotective effect after traumatic brain injury

Both progesterone and vitamin D have demonstrated neuroprotective effects on the brain after abrain injury traumatic injury in past studies, so a group of researchers sought to evaluate the effect of combining them. This randomized clinical trial compared progesterone treatment alone and combined with vitamin D to a placebo group and found that the “recovery rate of patients with severe brain trauma in the group receiving progesterone and vitamin D together was significantly higher than that of progesterone [only] group, which was in turn higher than that of placebo group.”(Advanced Biomedical Research, 2012)

LINK to ABSTRACT Comparison of the administration of progesterone versus progesterone and vitamin D in improvement of outcomes in patients with traumatic brain injury: A randomized clinical trial with placebo group.

Vitamin C help patients recover from hearing loss

72 patients with sudden hearing loss of unknown cause participated in this study. 36 patients served hearing lossas a control group that received steroid treatment for 15 days and 36 patients received the same steroid treatment plus high dose vitamin C intravenously daily for 10 days. Auditory evaluations were administered and the recovery rate of the group receiving vitamin C was more than twice that of the control group. (European Archives of Oto-rhino-laryngology, December 2012) 

LINK to ABSTRACT Effect of high dose intravenous vitamin C on idiopathic sudden sensorineural hearing loss: a prospective single-blind randomized controlled trial.

Mechanism behind serine's role for proper brain function is uncovered

Serine is a crucial amino acid needed to form proper synapses in the brain. It acts as abrain neurotransmitter and regulates NMDA(N-methyl-D-aspartate) receptors in the brain, which regulate mood and sleep, explaining its role in psychiatric and neurological disease. A recent study showed that serine supplementation could reverse oxidative stress-induced deficits in cognitive function.(Current Opinion in Clinical Nutrition and Metbolic Care, January 2013), (Aging Cell, April 2012), (Journal of Biological Chemistry, June 2012), (Biochemical Journal, 2003)

LINK to ABSTRACT D-Serine: physiology and pathology.
LINK to ABSTRACT Reversal of age-related oxidative stress prevents hippocampal synaptic plasticity deficits by protecting D-serine-dependent NMDA receptor activation.
LINK to ABSTRACT Resurgence of serine: an often neglected but indispensable amino acid.
LINK to ABSTRACT L-serine in disease and development. 
LINK to FREE FULL TEXT

For more educational resources visit our Clinical Education Center  

 

Topics: SpectraCell, Antidepressants, Autoimmunity, autoimmune diseases, folate, Vitamin D, Vitamin C, B Vitamins, Folic Acid, Antioxidants, Vitamin B12, immune system, Vitamins, Fertility, Case Study, Hearing, Depression, Brain, Hepatitis, anxiety

Clinical Applications of MTHFR Genomic Testing

Posted by SpectraCell Laboratories, Inc. on Tue, Jan 22, 2013 @ 03:50 PM

Clinical Applications of MTHFR Genomic Testing webinar presented by Dr. Bridget Briggs
 
What you learned:  Dr. Briggs, MTHFR
  • Methylation processes in the body. 
  • The function of MTHFR and the common polymorphisms found in 40% of Americans
  • The links between the common polymorphisms in MTHFR and risks involving cardiovascular disease, thromboembolic disease, irritable bowel, depression, memory agility, autoimmunity, poor detoxification, infertility, PMS, insomnia and many other disorders. 
  • Treatment for patients with common polymorphisms including L-5 MTHF, Methylcobalamin, B6, Trimethylglycine, inositol, and other key nutrients.

  • Case Study Review

Clinical Applications of MTHFR Genomic Testing Webinar

 

Topics: SpectraCell, Autoimmunity, cancer cells, autoimmune diseases, Telomere testing, B Vitamins, Fibromyalgia, ApoE Genotyping, Cardiovascular Health, diagnostic tools, MTHFR Genotyping, Genotyping, Multivitamins, Chronic Disease, immune system, breast cancer, deficiencies, Elderly, chronic fatigue and nutrition, health, Case Study, Inflammatory Bowel Disease, degenerative illness, Cancer Prevention, Heart Health, Gastrointestinal Tract, cardiovascular disease, Energy, Methylation, Immunidex, Immunity, eczema and nutrition, Genetics, Bowel Disease, Controversy, Dr. Bridget Briggs, Women's Health

Autoimmune Update: CoQ10, A New Biomarker for Parkinson's Disease?

Posted by SpectraCell Laboratories, Inc. on Wed, Jun 06, 2012 @ 05:37 PM

Parkinson's DiseaseGuest Blog by: Dr. Karl R.O.S. Johnson (D.C.)

As I have explained in another post, my father, grandfather and grandmother all had Parkinson's disease. This study shows promise for current sufferers and adds credence to the concept of why cell membranes need adequate antioxidant protection.You can be sure I take several different antioxidants in addition to eating a large variety of vegetables and fruits known to be rich in antioxidants. It's easy to obtain antioxidants if you eat a lot of colorful fresh fruits and vegetables.

Sir William Richard Gowers Parkinson Disease sketch 1886 2Autoimmune diseases such as Parkinson's disease, Hashimoto's and Celiac disease are all on the rise in the United States and throughout much of the world.

"Studies show that the incidence of multiple sclerosis in Padova, Italy, has risen from less than 100,000 cases in 1979 to over 400,000 in 1999. In Finland, incidence of type 1 diabetes has more than doubled in children in the past 30 years. Additionally, in the United States, celiac disease is more than four times more common today than it was 50 years go. Be sure to read my blog post entitled:
Ten Things You Didn't Know About Gluten and Autoimmune Illness

"These studies show an alarming trend that we believe is occurring throughout the United States and the world. Researchers think that this increase is due to a combination of genetic predisposition and environmental factors. It is imperative that more research projects are developed to explore what in our environment is causing this increased prevalence. Additionally, there is a need to identify more biomarkers in women to determine predisposition to autoimmune diseases so that prevention might be a possibility." (An excerpt from Virginia Ladd's testimony, March 4, 2009)

Autoimmunity is a result of a misdirected immune system that causes one's own immune system to attack the self. There are over 80 known autoimmune diseases. Some of the over 80 autoimmune diseases are lupus, type I diabetes, scleroderma, celiac, multiple sclerosis, Crohn's disease, autoimmune hepatitis, rheumatoid arthritis, Graves' disease, myasthenia gravis, myositis, antiphospholipid syndrome (APS), and Sjogren's syndrome.

The headline for this blog post refers to a study in which 22 patients with Parkinson's Disease were compared to 88 age-matched controls that did not have Parkinson's. Functional levels of several antioxidants - coenzyme Q10, glutathione, selenium, vitamin E and lipoic acid - were measured using SpectraCell's micronutrient testing. A deficiency of CoQ10 occurred in 32% of Parkinson's patients while only 8% of controls were deficient in CoQ10. Interestingly, this was not true for any other antioxidants, leaving authors to conclude that measuring CoQ10 status could determine which Parkinson's patients would benefit from CoQ10 supplements, which has proven to slow the progression of Parkinson's in various clinical trials. (Journal of Neurological Science, April 2011)

LINK to ABSTRACT Coenzyme Q10 deficiency in patients with Parkinson's Disease.
LINK to ABSTRACT Coenzyme Q10 for Parkinson's disease.

Dr. Karl Johnson

Dr. Karl R.O.S. Johnson, D.C. - Help My Chronic Condition & Pain

For more information about our client Dr. Johnson, please visit his website or his blog. Or contact him at (586) 731-8840.

Topics: Coenzyme Q10, Autoimmunity, Parkinsons disease

Nutritional Deficiencies From Gluten Intolerance Worsens Autoimmunity

Posted by SpectraCell Laboratories, Inc. on Tue, Apr 03, 2012 @ 01:33 PM

Gluten IntoleranceGuest Blog by: Dr. Karl R.O.S. Johnson (D.C.)

If you have gluten intolerance like I do, you will have nutritional deficiencies. Nutritional deficiencies can lead to a wind up of the immune system thereby worsening autoimmunity and/or the devlopment of additional diseases. Often only iron, sodium and postasium levels are checked on routine blood tests.

You Owe It To Yourself To Get Your Nutrient Levels Checked

Many researchers feel this paltry testing is not comprehensive enough. Deficiencies of magnesium, B vitamins, vitamin C, vitamin K, omega 3 fats, amino acids, glutathione and other important micronutrients are typically lowered with gluten intolerance. This is mainily due initially to increased systemic inflammation, which places a greater burden on the enzymes of detoxification as well as other enzymes.

Chemical reactions in our body are catalyzed by enzymes, and vitamins and minerals are the co-factors that allow enzymes to work. Enzymes cannot function without adequate vitamins. Just as your car cannot work without the ignition key or tires, enzymes are stalled without minerals and vitamins.

Micronutrient TestingOne of the best ways to measure vitamins and other micronutrients is through SpectraCell Micronutrient Testing. This patented process resulted from 18 years of research at the University of Texas. The micronutrient test measures the biochemical function of vitamins, minerals, amino acids and antioxidants, providing me a powerful clinical assessment tool in order to help you recover your health.

Signs of nutritional deficiencies on standard blood tests are high homocysteine levels, high MCV and MCH as well as low iron, potassium, protein and albumin. All these and other markers of body malfunction are easier to detect using functional blood chemistry analysis and can be missed using the typical standard broad average lab ranges. Using functional blood chemistry analysis is an important and unique reason why I often am able to detect earlier signs of health deterioration. Check out the link to my functional blood chemistry analysis page for more information on this topic.

When your body enzymes are less able to function due to nutritional deficiencies, autoimmune processes get a chance to ramp up, leading to additional tissues to be targeted for attack.Human Body

Results: Coeliac patients showed a higher total plasma homocysteine level than the general population, indicative of a poor vitamin status. In accordance, the plasma levels of folate and pyridoxal 5″-phosphate (active form of vitamin B-6) were low in 37% and 20%, respectively, and accounted for 33% of the variation of the total plasma homocysteine level (P < 0.008). The mean daily intakes of folate and vitamin B-12, but not of vitamin B-6, were significantly lower in coeliac patients than in controls.
 
Conclusions: Half of the adult coeliac patients carefully treated with a gluten-free diet for several years showed signs of a poor vitamin status. This may have clinical implications considering the linkage between vitamin deficiency, elevated total plasma homocysteine levels and cardiovascular disease. The results may suggest that, when following up adults with coeliac disease, the vitamin status should be reviewed."[1]

The bottom line take away message is this: It's not enough to treat the symptoms of an illness or disease. The prudent clinician will look for underlying causes of imbalances in the patients' bodily processes, and work with the patient to regain balance. Often this is accomplished with dietary changes, specific supplementation, lifestyle changes and neurological rehabilitation.

Dr. Carl Johnson

Dr. Karl R.O.S. Johnson, D.C. - Help My Chronic Condition & Pain

For more information about our client Dr. Johnson, please visit his website or his blog. Or contact him at (586) 731-8840.

Contact our bloggers at spec1@spectracell.com.

Topics: micronutrient testing, Autoimmunity, Nutritional Deficiency, Dr. Karl R.O.S. Johnson, Celiac, Gluten Intolerance