SpectraCell Blog

Vitamins, minerals and antioxidants can help!

Posted by SpectraCell Laboratories, Inc. on Thu, Jan 10, 2013 @ 01:20 PM

Is carnitine the answer for male infertility?male, infertility
A group of men (n=96) who had been diagnosed as infertile for at least 18 months were given the following nutritional formulation daily for four months: L-carnitine, acetyl-L-carnitine, fructose, citric acid, selenium, coenzyme Q10, zinc, vitamin C, vitamin B12 and folic acid (see abstract for exact dosages).  At the end of the study, sperm motility improved and 16 of the patients had achieved pregnancy.  The authors concluded that carnitine may be the key component of the supplement cocktail for improving sperm quality. (Italian Archives of Urology and Andrology, September 2012)

LINK to ABSTRACT Prospective open-label study on the efficacy and tolerability of a combination of nutritional supplements in primary infertile patients with idiopathic astenoteratozoospermia.

 

Vitamin D helps leg ulcers heal
In this double-blind, placebo controlled trial, 26 patients Vitamins, Vitamin Dwith leg ulcers were given either placebo or 50,000 IU vitamin D weekly for two months.  Leg ulcer size, blood levels of vitamin D and pain was measured before and after the two month trial.  In the vitamin D group, leg ulcers were reduced in size by 28% while the placebo group had only a 9% reduction in ulcer size. The authors stated “there was a trend toward better healing in those with vitamin D reposition.” (Journal of Brazilian College of Surgeons, October 2012)

LINK to ABSTRACT Vitamin D and skin repair: a prospective, double-blind and placebo controlled study in the healing of leg ulcers.
LINK to FREE FULL TEXT

 

Complexity of methylation reactions gains insightmethyl donor, nutrients
This review emphasizes how methyl donor nutrients such as choline, folic acid and methionine interact and how consumption (via supplement or food) of one can have sparing effect s on another – such as choline’s  sparing effect on methionine, for example. (Current Opinion in Clinical Nutrition and Metabolic Care, January 2013)

LINK to ABSTRACT The nutritional burden of methylation reactions.
LINK to FLYER on NUTRIENT INTERACTIONS in METHYLATION

For more journal articles by disease or nutrient please click here

 

Topics: SpectraCell, serine, micronutrients, Coenzyme Q10, Oleic Acid, Cysteine, autoimmune diseases, zinc, Vitamin D, Carnitine, Magnesium, Choline, Vitamin C, Vitamin E, Vitamin A, Selenium, Vitamin B6, B Vitamins, Folic Acid, Antioxidants, lipoprotein particle profile, Omega 3 Fatty Acid, diagnostic tools, vitamin, wellness, pregnancy, Serum, Vitamin K, Vitamin B12, supplements, Multivitamins, Nutrition, diabetes, immune system, E-zinc, N-acetylcysteine, DNA, Calcium, Fertility, Lipoic Acid, deficiencies, health, Case Study, Omega 3s, Depression, Glutamine, Minerals, Neurotransmitters, Stress, Vitamin B1, micronutrient test, Vitamin B5, Vitamin B2, Nutritional Deficiency, Vitamin B3, cardiovascular disease, Hormones, Reproductive Health, Chromium, Manganese, Muscle recovery, Erectile Dysfunction, infertility, Niacin, Prostate, Energy, Methylation, Carbohydrate Metabolism

SpectraCell's Clinical Updates - Volume 6, Issue 4

Posted by SpectraCell Laboratories, Inc. on Mon, May 07, 2012 @ 11:59 AM

VitaminsCLINICAL UPDATE - SELENIUM: KNOW IF YOU HAVE TOO MUCH OF A GOOD THING
An exhaustive review of the benefits selenium has on human health emphasizes that there is a definite “U-shaped link with status.”  The paper epitomizes the philosophy that more-is-not-always-better for vitamins and minerals.  Although low selenium status has been linked to several diseases – heart disease, infertility, low immunity, poor cognitive function, thyroid disease and cancer – the authors state that although “additional selenium intake may benefit individuals with low status, those with adequate status might be affected adversely and should not take selenium supplements.”  (Lancet, March 2012)

LINK to ABSTRACT Selenium and human health.

Heavy Metal ToxicityCLINICAL UPDATE - NUTRIENT DEFICIENCY CAUSING HEAVY METAL TOXICITY?
A case study on a 37 year old man suggests that multiple micronutrient deficiencies played a role in the cause of his multiple sclerosis.  The authors state he had several key nutrient deficiencies, which they think impaired his ability to excrete harmful metals.  They sate that “nutritional treatment may be an effective approach to this disease” due to the role of nutrients in various detoxification pathways. (Current Aging Science, Epub ahead of print in August 2011)

LINK to ABSTRACT Influence of Essential Trace Minerals and Micronutrient Insufficiencies on Harmful Metal Overload in a Mongolian Patient with Multiple Sclerosis.
 
Blood PressureCLINICAL UPDATE - META-ANALYSIS FINDS VITAMIN C SUPPLEMENTS LOWER BLOOD PRESSURE
In a review of 29 randomized controlled trials of oral vitamin C, authors found that vitamin C supplements reduced both systolic and diastolic blood pressure.  The reduction in blood pressure was more pronounced in people with existing hypertension.  In another meta-analysis, magnesium supplementation also lowered blood pressure. (American Journal of Clinical Nutrition, May 2012; European Journal of Clinical Nutrition, April 2012)

LINK to ABSTRACT Effects of vitamin C supplementation on blood pressure: a meta-analysis of randomized controlled trials.
LINK to ABSTRACT Effect of magnesium supplementation on blood pressure: a meta-analysis.

Oxidative Stress and HypothyroidismCLINICAL UPDATE - FOLIC ACID LOWERS OXIDATIVE STRESS IN HYPOTHYROIDISM
In two separate studies, antioxidant function was evaluated after hypothyroidism was induced.  Since basal metabolic rate is lower in hypothyroism and most oxidative stress in the body stems from basic metabolic functions, some researchers hypothesize that hypothyroidism should result in lower levels of oxidative stress.  But in this recent animal study, the authors found higher levels of oxidative stress in the hypothyroid (vs normal thyroid) state, as well as higher levels of homocysteine.  Treatment with folic acid ameliorated these effects.  In another study, authors found that hypothyroidism reduced antioxidant function, although the serum levels of several antioxidants. (vitamins A, C & E) remained constant. (Toxicology and Industrial Health, April 2012; Endokrynologia Polska, 2011)

LINK to ABSTRACT
The effect of folic acid as an antioxidant on the hypothalamic monoamines in experimentally induced hypothyroid rat.
LINK to ABSTRACT Elements of oxidation/reduction balance in experimental hypothyroidism.
LINK to FREE FULL TEXT
LINK to NUTRIENT INTERACTION CHART FOR HYPOTHYROIDISM

ToxicityCLINICAL UPDATE - COQ10 PROTECTS LIVER FROM ACETAMINOPHEN TOXICITY
A single toxic dose of acetaminophen was administered in an animal study and liver damage was monitored.  After 1 hour and after 12 hours, an injection of coenzyme Q10 was given. The results showed that the coQ10 injections protected the liver from acetaminophen-induced damage.  The coQ10 also attenuated the loss of zinc and selenium that occurred after acetaminophen administration. (Environmental Toxicology and Pharmacology, March 2012)

LINK to ABSTRACT Hepatoprotective effect of coenzyme Q10 in rats with acetaminophen toxicity.

Infertility and Vitamin ECLINICAL UPDATE - VITAMIN E MAY HELP INFERTILE WOMEN
103 women with unexplained infertility were divided into two groups – 50 women were given a drug to induce ovulation (clomiphene citrate) combined with 400IU per day of vitamin E and 53 women were induced to ovulate without the administration of vitamin E.  The supplemented group had a significantly thicker endometrium and authors suggest that vitamin E may be beneficial to women with unexplained infertility by improving the “endometrial response” and that it may “modulate the antiestrogenic effect of clomiphene citrate.” (Journal of Assisted Reproduction and Genetics, February 2012)

LINK to ABSTRACT Vitamin E effect on controlled ovarian stimulation of unexplained infertile women.

Carbohydrate MetabolismCLINICAL UPDATE - BIOTIN DEFICIENCY IMPAIRS CARBOHYDRATE METABOLISM
Researchers found that biotin deficiency negatively alters carbohydrate metabolism.  Specifically, biotin deficiency resulted in an impaired glucose and insulin tolerance test, suggesting “defects in insulin sensitivity,” according to the authors. (Journal of Nutritional Biochemistry, April 2012)

LINK to ABSTRACT Effects of biotin deficiency on pancreatic islet morphology, insulin sensitivity and glucose homeostasis.

Read more of our clinical updates in our archive!

 

Topics: Coenzyme Q10, Vitamin C, Vitamin E, Selenium, Folic Acid, biotin, Hypothyroidism, Oxidative Stress, infertility, Carbohydrate Metabolism, Blood Pressure, Heavy Metal Toxicity