SpectraCell Blog

Are you deficient in vitamin B3(Niacinamide)?

Posted by SpectraCell Laboratories, Inc. on Wed, Aug 21, 2013 @ 11:00 AM

Vitamin B3, also known as Niacin, is a water solubledescribe the image vitamin. It is not stored in the body, so we need to consume it daily. We need niacin for proper digestive function. Vitamin B3(Niacinamide) is needed to metabolize food into energy.  Niacinamide is converted into the coenzymes nicotinamide adenine dinucleotide (NAD) and NADP, which function in oxidation-reduction reactions essential for release of energy from carbohydrates, fats and proteins.  Niacin can also be synthesized by the body from tryptophan, although with low efficiency.

Deficiency Symptoms:

  • Anorexia
  • Muscular fatigue
  • Indigestion
  • Depression
  • Insomnia
  • Headaches
  • Glossitis
  • Skin Lesions

Severe Deficiency Symptoms:

  • Pellagra
  • Dermatitis
  • Dementia
  • Diarrhea
  • Tremors and Sores

Repletion Information:

Dietary sources of niacinamide are expressed as niacin equivalents, taking into account tryptophan's contribution.  Richest sources (per serving) include:

  • Nutritional Supplements
  • Meats
  • Enriched Cereals
  • Nutritional Yeasts
  • Legumes (including peanuts)
  • Potatoes
Case study where a patient demonstrated a deficiency in vitamin Bs, click here to read, also you can download a copy of the Nutrient correlation chart on Dyslipidemia and Insomnia

Interested in finding your micronutrient levels, please click here

Topics: SpectraCell, B Vitamins, Depression, micronutrient test, micronutrient, Vitamin B3, Niacin

Is vitamin B2(Riboflavin) important? YES

Posted by SpectraCell Laboratories, Inc. on Wed, Aug 14, 2013 @ 01:46 PM

Vitamin B2 more commonly known as vitamin B2Riboflavin is a micronutrient with a key role in maintaining health.  Vitamin B2(Riboflavin) helps to metabolize foodstuffs into energy.  Riboflavin(vitamin B2) is converted into its active forms, flavin adenine dinucleotide (FAD) and flavin mononucleotide (FMN).  FAD and FMN are primarily involved as cofactors in oxidation-reduction reactions for flavoproteins, essential for cellular energy production and respiration.  Vitamin B2(Riboflavin) has a role in antioxidant status by activating glutathione reductase, which regenerates reduced glutathione.


Vitamin B2(Riboflavin) Deficiency Symptoms:

  • Depression
  • Dizziness
  • sore or burning lips, mouth and tongue
  • Photophobia
  • Burning, itching or teary eyes
  • Loss of visual acuity

Severe vitamin B2 Deficiency symptoms:

  • Dermatitis
  • Cheilosis
  • Angular stomatitis
  • Corneal vascularization
Download SpectraCell's Nutrition Correlation chart referencing the correlation between vitamin B2(Riboflavin) with Depression as well as our Nutrient Depletion Chart
Click here to view our webinar on how nutrition can cure depression.

Interested in finding out your micronutrient levels, click here

Topics: SpectraCell, Vitamins, Case Study, Depression, micronutrient, vitamin deficiencies

Vitamin A - How does it AFFECT YOU!

Posted by SpectraCell Laboratories, Inc. on Thu, Aug 01, 2013 @ 11:47 AM

Vitamin A is a group of nutritionally unsaturated hydrocarbons. Different forms of the vitamin vitamin A include retinol, retinoic acid, and carotenoids. Retinol is the most biologically active form of vitamin A and is synthesized by pro-vitamin A(beta-carotene). Vitamin A regulates cell proliferation, differentiation, immune function and apoptosis (cell death).  This vitamin plays a vital role in night or low-light vision and color vision among many other common functions.

Symptoms of vitamin A deficiency - Impaired immune function; eye or skin problems; compromised cell growth and development; fat malabsorption; night blindness; zinc deficiency; insomnia.

Common conditions associated with vitamin A deficiency - Hormone balance, Immunidex, Insomnia, night blindness.

CASE STUDY highlights a common problem with a vitamin A deficiency. A 45 year old female with multiple conditions such as hypertension, insomnia and GERD, click here.

View our webinars Nutritional Considerations of Hormone Balance and Nutritional Considerations of Skin disorders, which references vitamin A deficiency among others in these conditions. 

To check your micronutrient levels or to get started click here

Topics: SpectraCell, micronutrients, micronutrient testing, Cancer, cancer cells, autoimmune diseases, zinc, Vitamin A, Migraines, Heart Disease, pregnancy, Multivitamins, immune system, E-zinc, breast cancer, Fertility, PMS, deficiencies, Case Study, Headache, Dr. Ron Grabowski, deficiency, Depression, degenerative illness, micronutrient test, Cancer Prevention, Hypothyroidism, Hormones, Menopause, HSVI, GERD, mitral valve prolapse, infertility, Immunidex, eczema and nutrition, Women's Health

Do the Prescriptions YOU take deplete your nutritional status?

Posted by SpectraCell Laboratories, Inc. on Wed, Jul 24, 2013 @ 03:34 PM

When a person takes prescription drugs or over the counter medication chances are that they can prescription depletions Page 1 resized 600 be affecting their nutrient levels. Below are some of the possible deficiencies that are correlated with each corresponding drug.

Antacids/Ulcer medications

  • vitamin B12 - Anemia, depression, tiredness, weakness, increased cardiovascular risk

  • Folic Acid - Birth defects, cervical dysplasia, anemia, heart disease, cancer risk

  • vitamin D - osteoporosis, muscle weakness, hearing loss

  • Calcium - Osteoporosis, heart and blood pressure irregularities, tooth decay

  • Iron - Anemia, weakness, fatigue, hair loss, brittle nails

  • Zinc - weak immunity, wound healing, sense of smell/taste, sexual dysfunction


Antibiotics

  • B vitamins, Vitamin K - short term depletion affects are minimal, but failure to re-inoculate the GI tract with beneficial bacteria (probiotics) often results in dysbiosis which causes gas, bloating, decreases digestion & absorption of nutrients, and also may lead to a variety of other health problems.

  • Calcium - osteoporosis, heart & blood pressure irregularities, tooth decay

  • magnesium - cardiovascular problems, asthma, osteoporosis, cramps, PMS

  • Iron - slow wound healing, fatigue, anemia

  • vitamin B6 - depression, sleep disturbance, increased cardiovascular disease risk

  • zinc - weak immunity, wound healing, sense of smell/taste, sexual dysfunction


Cholesterol drugs

  • Coenzyme Q10 - Various cardiovascular problems, weak immune system, low energy


Female Hormones

  • Vitamin B6 - depression, sleep disturbance, increased cardiovascular disease risk

  • Folic acid - birth defects, cervical dysplasia, anemia, cardiovascular disease

  • vitamin B1 - depression, irritability, memory loss, muscle weakness, edema

  • vitamin B2 - problems with skin, eyes, mucous membranes and nerves

  • vitamin B6 - depression, sleep disturbances, increased cardiovascular disease risk

  • vitamin B12 - anemia, depression, tiredness, weakness, increased cardiovascular risk

  • vitamin C - lowered immune system, easy bruising, poor wound healing

  • magnesium - cardiovascular problems, asthma, osteoporosis, cramps, PMS

  • selenium - lower immunity, reduced antioxidant protection'

  • zinc - weak immunity, wound healing, sense of smell/taste, sexual dysfunction


Anti-Inflammatories

  • calcium - osteoporosis, heart and blood pressure irregularities, tooth decay

  • vitamin D - osteoporosis, muscle weakness, hearing loss

  • magnesium - cardiovascular problems, asthma, osteoporosis, cramps, PMS

  • zinc - weak immunity, wound healing, sense of smell/taste, sexual dysfunction

  • vitamin C - lowered immunity, easy bruising, poor wound healing

  • vitamin B6 - depression, sleep disturbances,increased cardiovascular disease risk

  • vitamin B12 - anemia, depressioon, tiredness, weakness, increased cardiovascular risk

  • Folic Acid - birth defects, cervical dysplasia, anemia, cardiovascular disease

  • Selenium - lower immunity, reduced antioxidant protection

  • chromium - elevated blood sugar, cholesterol & triglycerides, diabetes risk

  • vitamin B5 - fatigue, listlessness, and possible problems with skin, liver and nerves

For a complete list of drugs and their correlating deficiencies click here

If you would like to check your nutrient levels click here

Topics: SpectraCell, micronutrients, Coenzyme Q10, Antidepressants, Cancer, autoimmune diseases, zinc, Vitamin D, Carnitine, Magnesium, Vitamin C, Vitamin E, Vitamin B6, B Vitamins, Folic Acid, Antioxidants, Fibromyalgia, Cholesterol, Cardiovascular Health, Heart Disease, Vitamin K, Vitamin B12, Chronic Disease, diabetes, immune system, E-zinc, Vitamins, Calcium, Fertility, PMS, deficiencies, chronic fatigue and nutrition, health, Inflammatory Bowel Disease, Depression, Diet, Digestion, Stress, Vitamin B1, micronutrient test, Inflammation, Vitamin B5, High Blood Pressure, Vitamin B2, Iron, Nutritional Deficiency, Cancer Prevention, Heart Health, Gastrointestinal Tract, Hypothyroidism, Allergies, Wound Healing, Vitamin B3, Antihistamines, cardiovascular disease, Nutrient, hypertension, Women's Health

Theories, Research and Treatment with Vitamins and Antioxidants

Posted by SpectraCell Laboratories, Inc. on Thu, Mar 07, 2013 @ 09:31 AM

New theory on how vitamins work gains attention

A group of researchers in Europe proposed a new theory on how vitamins work in the body,vitamins displacing the former accepted view that vitamin molecules work directly on cells in the body. Their research, which used radiation and electron pulse technology, led them to conclude that antioxidant vitamins emit dissolved electrons that quench free radicals. They concluded that the well-known vitamin effects are attributed to “vitamin free radicals rather than the vitamin molecules per se, as generally accepted.”(Nutrition, January 2013)

Link to Abstract Vitamin-induced intracellular electrons are the mechanism for their well-known beneficial effects: A review.

Treatment resistant depression responds to folate therapy

Two randomized, double-blind trials were conducted in which depression, treatmentdepression patients who had a partial or no response to a SSRI (selective serotonin reuptake inhibitors) were given l-methylfolate for 60 days. In the first trial, the dosage of folate was 7.5mg/day for 30 days, then 15mg/day for 30 days. In the second trial, the dosage of folate was 15mg/day for 60 days. Patients in the second trial showed significantly greater efficacy of SSRI drugs (lower depression scores and significantly decreased symptom severity) compared to the first trial (where the dosage of folate was lower) and compared to placebo. (American Journal of Psychiatry, December 2012)

LINK to ABSTRACT  (L)-methylfolate as adjunctive therapy for SSRI-resistant major depression: results of two randomized, double-blind, parallel-sequential trial.
LINK to FLYER on NUTRIENT INTERACTIONS IN DEPRESSION

Antioxidant therapy benefits both anxiety and depression

Blood levels of the antioxidant (specifically, vitamins A, C and E) were measured in eighty patients ofantioxidant a psychiatric hospital that were diagnosed with stress-induced generalized anxiety disorder and depression. Supplements of each vitamin were given for six weeks and blood levels of each vitamin were measured again. After six weeks, blood levels of vitamin A and C had increased and there was a “significant reduction in anxiety and depression scores of patients.”(Indian Journal of Psychiatry, July2012)

LINK to ABSTRACT Role of antioxidants in generalised anxiety disorder and depression. 
LINK to FREE FULL TEXT
LINK to FLYER on NUTRIENT INTERACTIONS IN ANXIETY
LINK to FLYER on NUTRIENT INTERACTIONS IN DEPRESSION

Is B12 the magic bullet for hepatitis?

This paper concludes that B12 is particularly beneficial for hepatitis C viral therapy. Specifically, adding Vitamin B12vitamin B12 (5mg given intramuscularly every 4 weeks) to the conventional therapy of pegylated interferon plus ribavirin improved treatment response after 3 months. This confirms earlier research that shows vitamin B12 ca inhibit the hepatitis C virus in vitro.(Expert Review of Anti-Infective Therapy, November 2012)

LINK to ABSTRACT Vitamins? The magic bullet against hepatitis C.
LINK to FREE FULL TEXT

Vitamin D amplifies progesterone's neuroprotective effect after traumatic brain injury

Both progesterone and vitamin D have demonstrated neuroprotective effects on the brain after abrain injury traumatic injury in past studies, so a group of researchers sought to evaluate the effect of combining them. This randomized clinical trial compared progesterone treatment alone and combined with vitamin D to a placebo group and found that the “recovery rate of patients with severe brain trauma in the group receiving progesterone and vitamin D together was significantly higher than that of progesterone [only] group, which was in turn higher than that of placebo group.”(Advanced Biomedical Research, 2012)

LINK to ABSTRACT Comparison of the administration of progesterone versus progesterone and vitamin D in improvement of outcomes in patients with traumatic brain injury: A randomized clinical trial with placebo group.

Vitamin C help patients recover from hearing loss

72 patients with sudden hearing loss of unknown cause participated in this study. 36 patients served hearing lossas a control group that received steroid treatment for 15 days and 36 patients received the same steroid treatment plus high dose vitamin C intravenously daily for 10 days. Auditory evaluations were administered and the recovery rate of the group receiving vitamin C was more than twice that of the control group. (European Archives of Oto-rhino-laryngology, December 2012) 

LINK to ABSTRACT Effect of high dose intravenous vitamin C on idiopathic sudden sensorineural hearing loss: a prospective single-blind randomized controlled trial.

Mechanism behind serine's role for proper brain function is uncovered

Serine is a crucial amino acid needed to form proper synapses in the brain. It acts as abrain neurotransmitter and regulates NMDA(N-methyl-D-aspartate) receptors in the brain, which regulate mood and sleep, explaining its role in psychiatric and neurological disease. A recent study showed that serine supplementation could reverse oxidative stress-induced deficits in cognitive function.(Current Opinion in Clinical Nutrition and Metbolic Care, January 2013), (Aging Cell, April 2012), (Journal of Biological Chemistry, June 2012), (Biochemical Journal, 2003)

LINK to ABSTRACT D-Serine: physiology and pathology.
LINK to ABSTRACT Reversal of age-related oxidative stress prevents hippocampal synaptic plasticity deficits by protecting D-serine-dependent NMDA receptor activation.
LINK to ABSTRACT Resurgence of serine: an often neglected but indispensable amino acid.
LINK to ABSTRACT L-serine in disease and development. 
LINK to FREE FULL TEXT

For more educational resources visit our Clinical Education Center  

 

Topics: SpectraCell, Antidepressants, Autoimmunity, autoimmune diseases, folate, Vitamin D, Vitamin C, B Vitamins, Folic Acid, Antioxidants, Vitamin B12, immune system, Vitamins, Fertility, Case Study, Hearing, Depression, Brain, Hepatitis, anxiety

SpectraCell's Nutritional Correlation Chart on Autism

Posted by SpectraCell Laboratories, Inc. on Wed, Feb 06, 2013 @ 01:54 PM

Autism Nutritional WheelVitamin D - High dose vitamin D therapy reversed autistic behaviors in severely deficient children; Maternal vitamin D deficiency may predispose children to autism.3,4,5

Vitamin A - One cause of autism may be a defect in a retinoid receptor protein (G-alpha protein) which is critical for language processing, attention and sensory perception; Evidence suggests natural vitamin A fixes this protein defect in autistics.1,2

Folate - Oral folate therapy can resolve symptoms of autism in some cases, particularly in autistics with genes that impair folate dependent enzymes.31,32,33

Glutamine - Blood levels of this amino acid which acts as a neurotransmitter are particularly low in autistics. Glutamine also helps prevent leaky gut syndrome, which can exacerbate autistic symptoms.28,29,30

Vitamin C - Improved symptom severity and sensory motor scores in autistic patients possibly due to interaction with dopamine synthesis; Vitamin C also has a strong sparing effect on glutathione.26,27

Glutathione & Cysteine -  Commonly deficient in autistic patients, lack of these antioxidants impair detoxification and methylation processes; Low levels linked to neurological symptoms in autism which is often considered an oxidative stress disorder.21,22,23,24,25

Vitamin B1 - Deficiency linked to delayed language development; Supplementation may benefit autistic patients.19,20

Vitamin B12 - Low B12 impairs methylation (detoxification) which causes the neurological damage responsible for many autistic symptoms; Deficiency of B12 can cause optic neuropathy and vision loss in autistics; B12 raises cysteine and glutathione levels.16,17,18

Vitamin B6 - Cofactor the neurotransmitters serotonin and dopamine; Conversion of B6 to its active form is compromised in many autistics; Supplementation trials with B6 resulted in better eye contact, speech and fewer self-stimulatory behavior in autistics; Some consider B6 in combination with magnesium to be a breakthrough treatment for autism.14,15

Magnesium - Cofactor for the neurotransmitters that affect social reactions and emotion; Autistics have low levels; Improves effectiveness of B6 therapy.11,12,13

Zinc - Eliminates toxic mercury from brain tissue; Zinc/ copper ratio is particularly low in autistic kids; Low zinc impairs  the protein (called metallothionein) that removes heavy metals from the body.8,9,10

Carnitine - Transports fatty acids into cells; Low carnitine (common in autism) impairs the ability to use fatty acids for learning and social development.6,7

 For a copy of Spectracell's Nutrition Correlation chart on Autism click here

Topics: micronutrients, micronutrient testing, Cysteine, Antidepressants, zinc, folate, Vitamin D, Carnitine, Magnesium, Vitamin C, Vitamin A, Vitamin B6, B Vitamins, Antioxidants, diagnostic tools, supplements, autism, Vitamins, DNA, deficiencies, health, deficiency, Depression, Glutamine, Neurology, Glutathione, Diet, Minerals, Digestion, Brain, Nervous System, Neurotransmitters, Aggression, Stress, Vitamin B1, degenerative illness, micronutrient test

Vitamins, minerals and antioxidants can help!

Posted by SpectraCell Laboratories, Inc. on Thu, Jan 10, 2013 @ 01:20 PM

Is carnitine the answer for male infertility?male, infertility
A group of men (n=96) who had been diagnosed as infertile for at least 18 months were given the following nutritional formulation daily for four months: L-carnitine, acetyl-L-carnitine, fructose, citric acid, selenium, coenzyme Q10, zinc, vitamin C, vitamin B12 and folic acid (see abstract for exact dosages).  At the end of the study, sperm motility improved and 16 of the patients had achieved pregnancy.  The authors concluded that carnitine may be the key component of the supplement cocktail for improving sperm quality. (Italian Archives of Urology and Andrology, September 2012)

LINK to ABSTRACT Prospective open-label study on the efficacy and tolerability of a combination of nutritional supplements in primary infertile patients with idiopathic astenoteratozoospermia.

 

Vitamin D helps leg ulcers heal
In this double-blind, placebo controlled trial, 26 patients Vitamins, Vitamin Dwith leg ulcers were given either placebo or 50,000 IU vitamin D weekly for two months.  Leg ulcer size, blood levels of vitamin D and pain was measured before and after the two month trial.  In the vitamin D group, leg ulcers were reduced in size by 28% while the placebo group had only a 9% reduction in ulcer size. The authors stated “there was a trend toward better healing in those with vitamin D reposition.” (Journal of Brazilian College of Surgeons, October 2012)

LINK to ABSTRACT Vitamin D and skin repair: a prospective, double-blind and placebo controlled study in the healing of leg ulcers.
LINK to FREE FULL TEXT

 

Complexity of methylation reactions gains insightmethyl donor, nutrients
This review emphasizes how methyl donor nutrients such as choline, folic acid and methionine interact and how consumption (via supplement or food) of one can have sparing effect s on another – such as choline’s  sparing effect on methionine, for example. (Current Opinion in Clinical Nutrition and Metabolic Care, January 2013)

LINK to ABSTRACT The nutritional burden of methylation reactions.
LINK to FLYER on NUTRIENT INTERACTIONS in METHYLATION

For more journal articles by disease or nutrient please click here

 

Topics: SpectraCell, serine, micronutrients, Coenzyme Q10, Oleic Acid, Cysteine, autoimmune diseases, zinc, Vitamin D, Carnitine, Magnesium, Choline, Vitamin C, Vitamin E, Vitamin A, Selenium, Vitamin B6, B Vitamins, Folic Acid, Antioxidants, lipoprotein particle profile, Omega 3 Fatty Acid, diagnostic tools, vitamin, wellness, pregnancy, Serum, Vitamin K, Vitamin B12, supplements, Multivitamins, Nutrition, diabetes, immune system, E-zinc, N-acetylcysteine, DNA, Calcium, Fertility, Lipoic Acid, deficiencies, health, Case Study, Omega 3s, Depression, Glutamine, Minerals, Neurotransmitters, Stress, Vitamin B1, micronutrient test, Vitamin B5, Vitamin B2, Nutritional Deficiency, Vitamin B3, cardiovascular disease, Hormones, Reproductive Health, Chromium, Manganese, Muscle recovery, Erectile Dysfunction, infertility, Niacin, Prostate, Energy, Methylation, Carbohydrate Metabolism

Can Nutrition Cure Depression?

Posted by SpectraCell Laboratories, Inc. on Fri, Dec 21, 2012 @ 11:09 AM

Presented by: Mary Ann Block, D.O.Depression, sad, nutrition

Topics of Discussion:

    • How Depression is Often a Symptom of Underlying Medical Problems
    • Nutrients Depleted by Antidepressants
    • Role of Zinc in the Development and Treatment of Mood Disorders
    • Case Study Review

 

Download our archived webinar presentation, "Can Nutrition Cure Depression?"

 

Also, check our webinar library for a complete list of previous webinars on a wide range of topics.

 

Topics: micronutrient testing, Antidepressants, autoimmune diseases, zinc, Vitamin D, Carnitine, Magnesium, Vitamin B6, B Vitamins, Antioxidants, Fatigue, Cholesterol, diagnostic tools, wellness, Vitamin B12, Multivitamins, Chronic Disease, E-zinc, deficiencies, chronic fatigue and nutrition, inositol, health, Case Study, website, Depression, Diet, Digestion, micronutrient test, Vitamin B2, Vitamin B3, Energy, Bipolar, webinar, Blood Pressure, Amino Acid, caffeine, Women's Health

SpectraCell's Nutritional Correlation Chart on DEPRESSION

Posted by SpectraCell Laboratories, Inc. on Thu, Sep 20, 2012 @ 05:52 PM

Depression WheelBelow is a list of various nutrients that affect a person affected with depression.
  • Chromium - Elevates serotonin (feel-good neurotransmitter) levels in the brain; May be particularly effective on eating symptoms of depression such as carbohydrate craving and increased appetite, due to its effect on blood sugar regulation.
  • Magnesium - Deficiency damages NMDA (N-methyl-D-aspartate) receptors in the brain, which regulate mood; Well-documented anti-depressant effects.
  • Vitamin B12 - Depression may be a manifestation of B12 deficiency; Repletion of B12 to adequate levels can improve treatment response; B12 deficiency common in psychiatric disorders.
  • Vitamin B6 - Cofactor for serotonin and dopamine production (feel good chemicals); Studies indicate that low levels may predispose people to depression.
  • Vitamin B2 - Low B2 has been implicated in depression due to its role in methylation reactions in the brain.
  • Vitamin D - Clinical trials suggest increasing blood levels of vitamin D, which is actually a hormone precursor, may improve symptoms of depression.
  • Carnitine - Increases serotonin and noradrenaline which lift mood; In trials, carnitine alleviates depression with few, if any, side effects.
  • Inositol - Influences signaling pathways in the brain; Particularly effective in SSRI  (selective serotonin reuptake inhibitor) sensitive disorders.
  • Biotin - Part of the B-vitamin complex, biotin deficiency has induced depression in animal and human studies.
  • Antioxidants - Oxidative stress in the brain alters neurotransmitter function; Antioxidants protect our brain, which is very sensitive to oxidation; Several antioxidants – Vitamins A, C and E, Lipoic Acid, CoQ10, Glutathione and Cysteine – play a key role in prevention and treatment of depression.
  • Serine - Regulates brain chemistry; Involved in NMDA receptor function; Acts as a neurotransmitter; Low levels correlate with severity of depression.
  • Zinc - Improves efficacy of antidepressant drugs; Particularly useful for treatment resistant patients; Regulates neurotransmitters.
  • Selenium - Integral part of regulatory proteins (selenoproteins) in the brain; Supplementation trials are promising; May alleviate postpartum depression.

To learn more, visit our Clinical Education Center's handouts section!

 

 

Topics: serine, zinc, Vitamin D, Carnitine, Magnesium, Selenium, Vitamin B6, Antioxidants, Vitamin B12, biotin, inositol, Depression, Vitamin B2, Chromium

SpectraCell's Clinical Updates - Volume 6, Issue 5

Posted by SpectraCell Laboratories, Inc. on Thu, May 31, 2012 @ 03:57 PM

Parkinson's DiseaseCLINICAL UPDATE - COQ10 A NEW BIOMARKER FOR PARKINSON'S DISEASE?
In this study, 22 patients with Parkinson’s Disease were compared to 88 age-matched controls that did not have Parkinson’s.  Functional levels of several antioxidants – coenzyme Q10, glutathione, selenium, vitamin E and lipoic acid – were measured using SpectraCell’s micronutrient testing.  A deficiency of CoQ10 occurred in 32% of Parkinson’s patients while only 8% of controls were deficient in coQ10.  Interestingly, this was not true for any other antioxidants, leaving authors to conclude that measuring coQ10 status could determine which Parkinson’s patients would benefit from coQ10 supplements, which has proven to slow the progression of Parkinson’s in various clinical trials. (Journal of Neurological Science, April 2012; Cochrane Database of Systematic Reviews, December 2011)

LINK to ABSTRACT Coenzyme Q10 deficiency in patients with Parkinson's disease.
LINK to ABSTRACT Coenzyme Q10 for Parkinson's disease.

Vitamin D and TestosteroneCLINICAL UPDATE - LOW VITAMIN D AND TESTOSTERONE IS A DEADLY COMBINATION
Testosterone and vitamin D was measured in over 2000 men. Those with a deficiency in both vitamin D and testosterone were more than twice as likely to have a fatal cardiovascular event and over 1 ½ times as likely to have a fatal event that was non- cardiovascular related. (Clinical Endocrinology, February 2012)

LINK to ABSTRACT Combination of low free testosterone and low vitamin D predicts mortality in older men referred for coronary angiography.

DepressionCLINICAL UPDATE - SMALL CHANGES IN OMEGA 3 INDEX = BIG CHANGES IN DEPRESSION RATES
Omega 3 index and fatty acids were measured in 150 adolescents that had been hospitalized for depression and compared to 161 controls.  For a 1% increase in the omega 3 index, teenagers were 28% less likely to have severe depression.   The omega 3 index is a measure of eicosapentaenoic acid (EPA) and docosahexanoeic acid (DHA) in red blood cells, which is correlates to fatty acid content in other tissues as well. (Prostaglandins, Leukotrienes and Essential Fatty Acids, April 2012)

LINK to ABSTRACT Red blood cell fatty acids are associated with depression in a case-control study of adolescents.

Choline and OffspringCLINICAL UPDATE - CHOLINE STATUS OF MOM AFFECTS HORMONE LEVELS IN OFFSPRING
Pregnant women were given either 930 or 480 mg/day of choline in their third trimester.  After twelve weeks, the group with higher choline intake had babies with less cortisol in their blood, possibly to due improved methylation of DNA in the placenta, which was also measured.  The authors concluded that maternal choline intake affects genes in the offspring that regulate cortisol production. (Federation of American Societies for Experimental Biology, May 2012)

LINK to ABSTRACT Maternal choline intake alters the epigenetic state of fetal cortisol-regulating genes in humans.

Pain and ShinglesCLINICAL UPDATE - INTRAVENOUS VITAMIN C REDUCES SHINGLES PAIN
In this study, 16 practioners gave vitamin C intravenously to 67 patients with symptomatic herpes zoster pain.  The dosage was 7.5 grams per 50 mL administered for two weeks.  Pain and skin eruptions associated with the shingles (herpes zoster) virus were significantly reduced for up to 12 weeks following injections. (Medical Science Monitor, April 2012)

LINK to ABSTRACT Intravenous Vitamin C in the treatment of shingles: Results of a multicenter prospective cohort study.
 
Trans FatsCLINICAL UPDATE - TRANS FATS LINKED TO AGGRESSION
Dietary intake of trans fat was estimated (via dietary survey) on 945 men and women and each rated their irritability and aggressive behaviours with a standardized test.  The authors of the study concluded that ‘this study provides the first evidence linking dietary trans fatty acids with behavioural irritability and aggression.” (PLoS One, 2012)

LINK to ABSTRACT Trans fat consumption and aggression.
LINK to FREE FULL TEXT

Browse our archive of all past clinical updates from the past 6 years!



Topics: Coenzyme Q10, Vitamin D, Choline, Vitamin C, Omega 3 Fatty Acid, Depression, Aggression, Hormones, Testosterone, Shingles, Trans Fats, Parkinsons disease