SpectraCell Blog

SpectraCell's Clinical Updates - Volume 6, Issue 7

Posted by SpectraCell Laboratories, Inc. on Thu, Aug 09, 2012 @ 10:37 AM

Omega 3sCLINICAL UPDATE - Omega 3s Can Replace Ibuprofen for PMS Pain
In this trial, a group of women were given either placebo or omega3 fatty acids for three months, followed by three months of the opposite regimen.  Symptoms of PMS, especially pain, were monitored. After 3 months of treatment, women who took the omega 3 capsules every day decreased their ibuprofen usage by 19% (first group) and by 53% (second group). (International Journal of Gynaecology and Obstetrics, April 2012)

LINK to ABSTRACT  Effect of omega-3 fatty acids on intensity of primary dysmenorrhea

AsthmaticsCLINICAL UPDATE - Carnitine Supplements Improve Lung Function in Asthmatics
A recent placebo-controlled study compared 50 children with asthma to 50 healthy controls and found that not only were levels of the amino acid carnitine lower in those with asthma, but supplementation with 350mg of L-carnitine daily for six months significantly improved lung function is those with asthma.   Researchers noted that carnitine’s primary role in transporting fatty acids into the mitochondria may explain its benefit to those with asthma – carnitine also transports fatty acids to lung membrane surfaces ensuring they are lubricated, explaining a mechanism by which carnitine improves pulmonary function. (Journal of Allergy, 2012)

LINK to ABSTRACT L-carnitine improves the asthma control in children with moderate persistent asthma.
LINK to FREE FULL TEXT
LINK to FLYER on NUTRIENT INTERACTIONS OF ASTHMA

DiabetesCLINICAL UPDATE - Vitamin C Benefits Diabetics on Metformin
Seventy patients with type II diabetes were given either placebo or 500mg vitamin C twice a day.  All patients were taking metformin as well. After twelve weeks, measures of blood sugar control (fasting blood sugar, post-meal blood glucose and HbA1c levels) were all improved in the vitamin C group only. (Advances in Pharmalogical Sciences, 2011)

LINK to ABSTRACT Supplementation of vitamin C reduces blood glucose and improves glycosylated hemoglobin in type 2 diabetes mellitus: a randomized, double-blind study.
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Brain InjuryCLINICAL UPDATE - Zinc: A New Role for Traumatic Brain Injury
In this review, the protective role of zinc against traumatic brain injury is elucidated.  The authors stat that human clinical data “suggest that zinc may increase resilience” and can be used “to improve cognitive and behavioural deficits associated with brain injury.” (Nutrition Reviews, July 2012)

LINK to ABSTRACT Improving treatments and outcomes: an emerging role for zinc in traumatic brain injury.

FertilityCLINICAL UPDATE - Vitamin E Increases Sperm Count
106 infertile men were included in this trial  – 64 were infertile due to low sperm count and 42 were infertile due to poor sperm motility.  They were divided into two groups – both groups received pharmaceutical therapy for fertility but only one group was simultaneously treated with a natural form of vitamin E.  Sperm count and motility improved more dramatically in the vitamin E treated group.  In fact, only five natural pregnancies occurred in the non-vitamin E group, while 15 natural pregnancies occurred in the vitamin E treated group.  In an unrelated trial, vitamin E was co-administered with fertility drugs to a group of women and compared to fertility drug treated women without vitamin E.  Although those treated with vitamin E did not have statistically higher rates of pregnancy, the women given vitamin E did show significantly improved endometrial thickness, which would facilitate future pregnancy. (Natural Journal of Andrology, May 2012; Journal of Assisted Reproduction and Genetics, April 2012)

LINK to ABSTRACT Efficacy of natural vitamin E on oligospermia and athenospermia: a prospective multi-centered randomized controlled study of 106 cases.
LINK to ABSTRACT Vitamin E effect on controlled ovarian stimulation of unexplained infertile women.

Muscle MassCLINICAL UPDATE - A New Role for Omega 3s in Building Muscle Mass
A group of women (average age = 64 years old) were put on a strength training program for 90 days.  Some of the women were given fish oil supplements while others received no supplement. Measures of muscle strength were taken and those taking fish oil showed significantly higher muscle development.  Researchers hypothesized that this increase in muscle development during strength training is due to the role omega 3 fatty acids play in plasma membranes and muscle cell function. (American Journal of Clinical Nutrition, February 2012)

LINK to ABSTRACT Fish-oil supplementation enhances the effects of strength training in elderly women.

SerineCLINICAL UPDATE - High Dose Serine Improves Neuropathy: Case Report
One of the most common inherited neurological disorders, Charcot-Marie-Tooth disease affects approximately 1 in every 2500 people and is characterized by muscle wasting and peripheral neuropathy. In this case report, a male patient with polyneuropathy had a serine synthesis defect.  Deficiency in the amino acid serine often manifests neurologically and in this case, high-dose supplementation of serine improved his neuropathy symptoms. (Archives of Neurology, March 2012)

LINK to ABSTRACT A Serine Synthesis Defect Presenting With a Charcot-Marie-Tooth-Like Polyneuropathy.

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Topics: serine, zinc, Carnitine, Vitamin C, Vitamin E, diabetes, Fertility, PMS, Omega 3s, Asthma

WEBINAR: Correlating Micronutrient Testing with Common Pathologies

Posted by SpectraCell Laboratories, Inc. on Mon, Jun 25, 2012 @ 03:13 PM

Micronutrient TestingPresented by: Ron Grabowski, R.D., D.C.

Topics of Discussion:
  • How do these results relate to the peer reviewed literature?
  • Correlating nutrient deficiencies with scientific evidence
  • Back to BioChemistry: Linking medications with deficiencies
  • Case Study Review: Addressing patient concerns
    • Diabetes Mellitus
    • Headaches
    • Inflammatory Bowel
    • Thyroid Function


Listen to the webinar or download the slides

Also, visit our Webinar Library in our Clinical Education Centerto listen to all of our archived webinars on various topics and conditions!

Topics: SpectraCell, micronutrient testing, diabetes, deficiencies, Headache, Inflammatory Bowel Disease, Thyroid

Nutritional Considerations of Diabetes

Posted by SpectraCell Laboratories, Inc. on Mon, Feb 06, 2012 @ 11:57 AM

DiabetesUNDERSTANDING DIABETES

According to the American Diabetes Association, type 2 diabetes is the most common form of diabetes. With this type of diabetes, cells do not receive enough insulin. As a result, cells starve for energy, and, over time, a glucose buildup in the blood stream causes negative effects on a person’s eyes, kidneys, nerves and/or heart.

Today’s fast-paced society has led to quicker, higher carbohydrate alternatives as food sources. As a result, there is a greater threat of developing diabetes due to cells becoming insulin-resistant.

Micronutrients such as niacin, magnesium, calcium, zinc, carnitine, inositol, alpha-lipoic acid, as well as vitamins E, B6 and D all play an important role in the prevention and treatment of diabetes.

Though diabetes is a serious disease - with the right treatment - living a longer, healthier life can be made easier.

THE ROLE OF MICRONUTRIENTS IN DIABETIC HEALTH

NIACIN
Niacin (nicotinamide) may help to preserve residual B-cell function in individuals with type 1 or type 2 diabetes. This B-vitamin is believed to be one of the components of the glucose tolerance factor (GTF).

MAGNESIUM
This mineral is involved in more than 300 enzymatic functions in the body. Magnesium deficiency has been associated with insulin resistance, glucose intolerance, dyslipidemia and hypertension, which have all been associated with diabetes mellitus. Magnesium has been found to be one of the more common micronutrient deficiencies in diabetes.

VITAMIN E
Low levels of vitamin E are associated with increased incidences of diabetes. Research suggests that individuals with diabetes mellitus have decreased levels of antioxidants. Increased antioxidant requirements may be a result of increased free radical production during periods of hyperglycemia.

ALPHA-LIPOIC ACID (THIOCTIC ACID)
This antioxidant has been shown to regenerate other antioxidants such as glutathione, vitamin E and vitamin C. Alpha-lipoic acid has been shown to enhance glucose uptake in skeletal muscle tissue, thus improving glucose regulation in diabetic mellitus individuals. In addition, this antioxidant can be beneficial in the treatment of diabetic polyneuropathy.

VITAMIN D
Obesity is often associated with vitamin D deficiency and also with type 2 diabetes. Research indicates that diabetic individuals (both type 1 and type 2) have a higher risk for bone fracture. This vitamin deficiency has clearly been associated with lower bone density. Subjects with hypovitaminosis D are at higher risk of insulin resistance and metabolic syndrome.

CHROMIUM
This trace mineral is fundamental in proper insulin function and is believed to facilitate the attachment of insulin to the cell’s insulin receptors. A lack of chromium can lead to insulin resistance, which leads to elevated blood levels of insulin and glucose. Elevated levels of glucose in the blood can lead to diabetes and cardiovascular complications. Food processing
removes most of naturally occurring chromium. However, chromium can be supplemented or found in brewer’s yeast, nuts, meat, whole grains, green beans and broccoli.

HOMOCYSTEINE
Homocysteine elevation is a risk factor for overall mortality in type 2 diabetic individuals independent of other risk factors. Adequate levels of pyroxidine (vitamin B6), folate and vitamin B12 are required for normal homocysteine metabolism.

MicronutrientsINOSITOL
This nutrient is found in high concentrations in peripheral nerves. There is some evidence that inositol may be effective in the treatment of diabetic neuropathy.

VITAMIN B6
Research shows that a deficiency of vitamin B6 may result in abnormal glucose tolerance, degeneration of the pancreatic beta cells, reduced insulin response to glucose and reduced serum and pancreatic insulin levels. In addition, vitamin B6 deficiency has been associated with polyneuropathies.

CALCIUM
Studies have shown that individuals with a low intake of calcium have an increased risk of non-insulin dependant diabetes mellitus. Numerous studies have also revealed that diabetes may be associated with abnormal regulation of intracellular calcium.

ZINC
This mineral has been associated with over 200 enzymatic functions in the body. Increased fasting blood glucose levels have been associated with low zinc. Zinc has been shown to be important in the synthesis, storage and secretion of insulin. Increased urinary zinc excretion has also been associated with diabetic individuals.

CARNITINE
This amino acid in the form of acetyl-L-carnitine has been shown to benefit those individuals with diabetic polyneuropathy. One of the proposed mechanisms is that this amino acid may restore the depleted nerve myoinositol content and decrease free radical production.

Topics: Homocysteine, Alpha-Lipoic Acid, zinc, Vitamin D, Carnitine, Magnesium, Vitamin E, Vitamin B6, diabetes, Calcium, inositol, Chromium, Niacin

'Nutrient Deficiencies Say More than Just the Absence of a Nutrient' by Dr. Arland Hill

Posted by Tara Stepan on Thu, May 12, 2011 @ 10:35 AM

 

Dr. Arland HillMicronutrient testing can be a real asset to the practicing clinician trying to help restore basic metabolic needs of their patients.  After all, nutrients power the various metabolic processes.  Without their availability, metabolic function is slowed or in some cases even brought to a stand still depending on the level of the nutrient deficiency.  Research has shown that over time, lack of nutrients can be lead to dysfunction and ultimately disease states.  Sometimes just restoring a single nutrient deficiency can have profound impact on the health of the patient and really help turn a corner, but this is the exception rather than the rule.

The true utility of SpectraCell’s micronutrient testing lies not in the analysis of individual nutrient deficiencies, but rather in the concept of observing patterns of nutrient deficiencies.  This is not to say that looking at individual nutrient deficiencies is not valid, but rather is an emphasis on the idea that with pattern identification, one can better have an idea of where to focus attention.

To better understand this concept, it is ideal to take a clinical scenario that may present.  Let us look at dysglycemia, or blood glucose dysregulation.  Those dealing with this condition are a fast growing segment of the population.  Yet these individuals don’t just manifest dyslglycemia overnight.  Rather they transition through a continuum that often begins with symptomatic reactive hypoglycemia, leading on to insulin resistance and ultimately diabetes if left untreated.  What if you had a method to tell your patients that they were in this pattern and that by addressing some of their nutrient deficiencies, you could help delay or even prevent the onset of dysglycemia.  A micronutrient test showing a nutrient pattern of nutrient deficiencies including B3, zinc, chromium, alpha lipoic acid and of course glucose-insulin interaction would suggest this very thing.

This is just one example, but it illustrates the breadth of information contained in the reports of the micronutrient test.  The reports provided by SpectraCell are not just a window into the intracellular health of the patient, but a tool with predictive abilities when appropriately assessed.  Noting the patterns within the test moves beyond the notion of just nutrient restoration, but allows one to see systems that must be supported to regain complete health and wellness.

Arland Hill, DC, MPH, DACBN                                                                 Complete Care Chiropractic and Wellness

 

Topics: SpectraCell, micronutrient testing, Alpha-Lipoic Acid, zinc, B Vitamins, wellness, Nutrition, diabetes, Glucose Intolerance, health, Chromium, metabolic processes, Dysglycemia, Blood Glucose Dysregulation