SpectraCell Blog

Sleep Apnea and the Correlation with Nutrients and Minerals

Posted by SpectraCell Laboratories, Inc. on Thu, Jun 13, 2013 @ 10:52 AM

Cysteine - Oral supplementation with cysteine, the precursor to glutathione, has therapeuticSleep Apnea, Nutrient Correlation Wheel potential for sleep apnea.  Snore time and duration were significantly reduced for patients treated with N-acetyl cysteine compared to untreated sleep apnea patients.

Antioxidant Status - It is well documented that sleep apnea patients have both reduced antioxidant capacity and higher levels of oxidative stress than controls.

Vitamin C - Improves endothelial function (blood vessel health) in sleep apnea patients to levels seen in people without sleep apnea.

Vitamin E - Mitigates the oxidative stress seen in sleep apnea patients; Works synergistically with Vitamin C.

Vitamin A - Sleep apnea patients have low retinol (vitamin A); Retinol suppresses the growth of vascular smooth muscle, a process that causes blood vessels to clog, linking low vitamin A levels to the cardiovascular complications seen in sleep apnea patients.

Vitamin D - People with sleep apnea have a high prevalence of vitamin D deficiency; The worse the apnea, the more severe the deficiency; Evidence suggests low vitamin D worsens sleep apnea's negative effect on heart disease risk.

Selenium - In one case report, selenium supplementation completely stopped snoring caused by non-obesity sleep apnea; Selenium's role as a potent antioxidant may reduce the oxidative stress seen in sleep apnea patients.

Copper - Considered a strong predictor of oxidative stress in sleep apnea patients; Copper's role as a key cofactor in the powerful antioxidant superoxide dismutase (SOD) explains this; SOD is very low in apnea patients.

Minerals - The trace minerals zinc, copper; magnesium, manganese and selenium are critical cofactors for the major antioxidant enzymes, which are important in repairing cellular damage caused by hypoxia (lack of oxygen) in sleep apnea.

Glutathione - Low levels linked to sleep apnea; This powerful antioxidant helps repair liver damage caused by sleep apnea.

Click to download your own copy of the Sleep Apnea Nutrient Correlation Wheel

Topics: micronutrients, micronutrient testing, Cysteine, Vitamin D, Vitamin C, Vitamin E, Vitamin A, Selenium, B Vitamins, Copper, Antioxidants, diagnostic tools, deficiencies, Glutathione, Minerals, micronutrient test, Dr. Fred Crawford, Sleep Apnea

SpectraCell's Nutritional Correlation Chart on Autism

Posted by SpectraCell Laboratories, Inc. on Wed, Feb 06, 2013 @ 01:54 PM

Autism Nutritional WheelVitamin D - High dose vitamin D therapy reversed autistic behaviors in severely deficient children; Maternal vitamin D deficiency may predispose children to autism.3,4,5

Vitamin A - One cause of autism may be a defect in a retinoid receptor protein (G-alpha protein) which is critical for language processing, attention and sensory perception; Evidence suggests natural vitamin A fixes this protein defect in autistics.1,2

Folate - Oral folate therapy can resolve symptoms of autism in some cases, particularly in autistics with genes that impair folate dependent enzymes.31,32,33

Glutamine - Blood levels of this amino acid which acts as a neurotransmitter are particularly low in autistics. Glutamine also helps prevent leaky gut syndrome, which can exacerbate autistic symptoms.28,29,30

Vitamin C - Improved symptom severity and sensory motor scores in autistic patients possibly due to interaction with dopamine synthesis; Vitamin C also has a strong sparing effect on glutathione.26,27

Glutathione & Cysteine -  Commonly deficient in autistic patients, lack of these antioxidants impair detoxification and methylation processes; Low levels linked to neurological symptoms in autism which is often considered an oxidative stress disorder.21,22,23,24,25

Vitamin B1 - Deficiency linked to delayed language development; Supplementation may benefit autistic patients.19,20

Vitamin B12 - Low B12 impairs methylation (detoxification) which causes the neurological damage responsible for many autistic symptoms; Deficiency of B12 can cause optic neuropathy and vision loss in autistics; B12 raises cysteine and glutathione levels.16,17,18

Vitamin B6 - Cofactor the neurotransmitters serotonin and dopamine; Conversion of B6 to its active form is compromised in many autistics; Supplementation trials with B6 resulted in better eye contact, speech and fewer self-stimulatory behavior in autistics; Some consider B6 in combination with magnesium to be a breakthrough treatment for autism.14,15

Magnesium - Cofactor for the neurotransmitters that affect social reactions and emotion; Autistics have low levels; Improves effectiveness of B6 therapy.11,12,13

Zinc - Eliminates toxic mercury from brain tissue; Zinc/ copper ratio is particularly low in autistic kids; Low zinc impairs  the protein (called metallothionein) that removes heavy metals from the body.8,9,10

Carnitine - Transports fatty acids into cells; Low carnitine (common in autism) impairs the ability to use fatty acids for learning and social development.6,7

 For a copy of Spectracell's Nutrition Correlation chart on Autism click here

Topics: micronutrients, micronutrient testing, Cysteine, Antidepressants, zinc, folate, Vitamin D, Carnitine, Magnesium, Vitamin C, Vitamin A, Vitamin B6, B Vitamins, Antioxidants, diagnostic tools, supplements, autism, Vitamins, DNA, deficiencies, health, deficiency, Depression, Glutamine, Neurology, Glutathione, Diet, Minerals, Digestion, Brain, Nervous System, Neurotransmitters, Aggression, Stress, Vitamin B1, degenerative illness, micronutrient test

Clinical Applications of MTHFR Genomic Testing

Posted by SpectraCell Laboratories, Inc. on Tue, Jan 22, 2013 @ 03:50 PM

Clinical Applications of MTHFR Genomic Testing webinar presented by Dr. Bridget Briggs
 
What you learned:  Dr. Briggs, MTHFR
  • Methylation processes in the body. 
  • The function of MTHFR and the common polymorphisms found in 40% of Americans
  • The links between the common polymorphisms in MTHFR and risks involving cardiovascular disease, thromboembolic disease, irritable bowel, depression, memory agility, autoimmunity, poor detoxification, infertility, PMS, insomnia and many other disorders. 
  • Treatment for patients with common polymorphisms including L-5 MTHF, Methylcobalamin, B6, Trimethylglycine, inositol, and other key nutrients.

  • Case Study Review

Clinical Applications of MTHFR Genomic Testing Webinar

 

Topics: SpectraCell, Autoimmunity, cancer cells, autoimmune diseases, Telomere testing, B Vitamins, Fibromyalgia, ApoE Genotyping, Cardiovascular Health, diagnostic tools, MTHFR Genotyping, Genotyping, Multivitamins, Chronic Disease, immune system, breast cancer, deficiencies, Elderly, chronic fatigue and nutrition, health, Case Study, Inflammatory Bowel Disease, degenerative illness, Cancer Prevention, Heart Health, Gastrointestinal Tract, cardiovascular disease, Energy, Methylation, Immunidex, Immunity, eczema and nutrition, Genetics, Bowel Disease, Controversy, Dr. Bridget Briggs, Women's Health

Vitamins, minerals and antioxidants can help!

Posted by SpectraCell Laboratories, Inc. on Thu, Jan 10, 2013 @ 01:20 PM

Is carnitine the answer for male infertility?male, infertility
A group of men (n=96) who had been diagnosed as infertile for at least 18 months were given the following nutritional formulation daily for four months: L-carnitine, acetyl-L-carnitine, fructose, citric acid, selenium, coenzyme Q10, zinc, vitamin C, vitamin B12 and folic acid (see abstract for exact dosages).  At the end of the study, sperm motility improved and 16 of the patients had achieved pregnancy.  The authors concluded that carnitine may be the key component of the supplement cocktail for improving sperm quality. (Italian Archives of Urology and Andrology, September 2012)

LINK to ABSTRACT Prospective open-label study on the efficacy and tolerability of a combination of nutritional supplements in primary infertile patients with idiopathic astenoteratozoospermia.

 

Vitamin D helps leg ulcers heal
In this double-blind, placebo controlled trial, 26 patients Vitamins, Vitamin Dwith leg ulcers were given either placebo or 50,000 IU vitamin D weekly for two months.  Leg ulcer size, blood levels of vitamin D and pain was measured before and after the two month trial.  In the vitamin D group, leg ulcers were reduced in size by 28% while the placebo group had only a 9% reduction in ulcer size. The authors stated “there was a trend toward better healing in those with vitamin D reposition.” (Journal of Brazilian College of Surgeons, October 2012)

LINK to ABSTRACT Vitamin D and skin repair: a prospective, double-blind and placebo controlled study in the healing of leg ulcers.
LINK to FREE FULL TEXT

 

Complexity of methylation reactions gains insightmethyl donor, nutrients
This review emphasizes how methyl donor nutrients such as choline, folic acid and methionine interact and how consumption (via supplement or food) of one can have sparing effect s on another – such as choline’s  sparing effect on methionine, for example. (Current Opinion in Clinical Nutrition and Metabolic Care, January 2013)

LINK to ABSTRACT The nutritional burden of methylation reactions.
LINK to FLYER on NUTRIENT INTERACTIONS in METHYLATION

For more journal articles by disease or nutrient please click here

 

Topics: SpectraCell, serine, micronutrients, Coenzyme Q10, Oleic Acid, Cysteine, autoimmune diseases, zinc, Vitamin D, Carnitine, Magnesium, Choline, Vitamin C, Vitamin E, Vitamin A, Selenium, Vitamin B6, B Vitamins, Folic Acid, Antioxidants, lipoprotein particle profile, Omega 3 Fatty Acid, diagnostic tools, vitamin, wellness, pregnancy, Serum, Vitamin K, Vitamin B12, supplements, Multivitamins, Nutrition, diabetes, immune system, E-zinc, N-acetylcysteine, DNA, Calcium, Fertility, Lipoic Acid, deficiencies, health, Case Study, Omega 3s, Depression, Glutamine, Minerals, Neurotransmitters, Stress, Vitamin B1, micronutrient test, Vitamin B5, Vitamin B2, Nutritional Deficiency, Vitamin B3, cardiovascular disease, Hormones, Reproductive Health, Chromium, Manganese, Muscle recovery, Erectile Dysfunction, infertility, Niacin, Prostate, Energy, Methylation, Carbohydrate Metabolism

The Importance of Vitamins

Posted by SpectraCell Laboratories, Inc. on Fri, Jan 04, 2013 @ 01:12 PM

New study says multivitamins just don’t cut it when it comes to preventing heart diseaseVitamins, multi-vitamins

In the landmark Physician’s Health Study II, authors concluded that taking a multivitamin for over a decade did nothing to prevent cardiovascular events such as myocardial infarction or stroke. The study monitored 14,641 male doctors for over eleven years who took either a daily multivitamin or placebo and no differences in cardiovascular events or mortality was found between the two groups.  Since evidence linking deficiencies to heart disease is strong (see vitamin D study below on 45,000 patients), some conclude that a multivitamin is simply not effective in correcting deficiencies and that targeted supplementation for the individual is a better approach. (Journal of the American Medical Association, November 2012)
(American Journal of Cardiology, October 2010)

Link to ABSTRACT Multivitamins in the prevention of cardiovascular disease in men: the Physicians' Health Study II randomized controlled trial.

Link to ABSTRACT Relation of vitamin D deficiency to cardiovascular risk factors, disease status, and incident events in a general healthcare population.

Vitamin C reduces fatigue and perception of effort after exercise

Vitamins, vitamin cIn this interesting study on twenty obese adults, each were given either 500 mg of vitamin C or placebo daily for four weeks.  Their diet was strictly controlled for vitamin C content and their heart rates and fatigue scores as well as subjective perceptions of exertion were measured after exercise.  Those taking vitamin C had lower fatigue scores and those on placebo had higher fatigue scores. Heart rates and “ratings of perceived exertion” were also improved in the vitamin C group. (Nutrition, January 2013)   

Link to ABSTRACT Vitamin C status and perception of effort during exercise in obese adults adhering to a calorie-reduced diet.

For more articles and information, click here for the complete library on clinical updates.

Topics: Coenzyme Q10, zinc, Vitamin D, Vitamin C, Vitamin E, Vitamin A, Vitamin B6, B Vitamins, Folic Acid, Copper, diagnostic tools, Heart Disease, vitamin, Vitamin K, Vitamin B12, supplements, Multivitamins, E-zinc, Vitamins, deficiencies, Heart Attack, Diet, Minerals, Vitamin B1, micronutrient test, Vitamin B5, High Blood Pressure, Vitamin B2, Heart Health, Vitamin B3, Aging, Stroke

Can Nutrition Cure Depression?

Posted by SpectraCell Laboratories, Inc. on Fri, Dec 21, 2012 @ 11:09 AM

Presented by: Mary Ann Block, D.O.Depression, sad, nutrition

Topics of Discussion:

    • How Depression is Often a Symptom of Underlying Medical Problems
    • Nutrients Depleted by Antidepressants
    • Role of Zinc in the Development and Treatment of Mood Disorders
    • Case Study Review

 

Download our archived webinar presentation, "Can Nutrition Cure Depression?"

 

Also, check our webinar library for a complete list of previous webinars on a wide range of topics.

 

Topics: micronutrient testing, Antidepressants, autoimmune diseases, zinc, Vitamin D, Carnitine, Magnesium, Vitamin B6, B Vitamins, Antioxidants, Fatigue, Cholesterol, diagnostic tools, wellness, Vitamin B12, Multivitamins, Chronic Disease, E-zinc, deficiencies, chronic fatigue and nutrition, inositol, health, Case Study, website, Depression, Diet, Digestion, micronutrient test, Vitamin B2, Vitamin B3, Energy, Bipolar, webinar, Blood Pressure, Amino Acid, caffeine, Women's Health

The Medical Insider Interviews SpectraCell Laboratories

Posted by SpectraCell Laboratories, Inc. on Tue, Jun 28, 2011 @ 04:05 PM

Dr. CrawfordThe Medical Insider - Don't Be Fooled Be Informed

Dr. Crawford, SpectraCell's Senior Vice President of Operations, was recently interviewed on the Medical Insider. On this radio program, he discussed micronutrient testing and current medical trends with Dr. Richard Powell and Dani Walker.

About Medical Insider:

Have you ever wondered if the information your doctor is sharing with you is the whole truth and nothing but the truth?  Has your doctor told you everything and given you every option available regarding your healthcare?  The Medical Insider takes an inside look at various modalities, therapies, medications, supplements and much more to bring you the up to date cutting edge information so you are empowered to make your own healthcare decisions.  A no-holds-barred discussion of what works, and what doesn't, from an allopathic, pharmaceutical as well as alternative healthcare perspective.  Don’t be fooled be informed with your hosts Dani Walker and Dr. Richard Powell.

Listen to the recorded interview HERE.

Also, feel free to visit The Medical Insider's website to listen to additional interviews and podcasts.

The Medical Insider

Topics: SpectraCell, micronutrient testing, diagnostic tools, Dr. Fred Crawford

Determine How Fast You Are Aging

Posted by SpectraCell Laboratories, Inc. on Thu, May 19, 2011 @ 11:41 AM

True Cellular Age

What are telomeres? Telomeres are sections of DNA at the end of each chromosome that serve as a cap to your genetic material. Every time a cell replicates, its telomere will become shorter. Shorter telomeres imply a shorter life span for a cell.

What effect does telomere length have on my health and wellness?

Age adjusted telomere length is the best method to date to assess biological age using structural analysis of chromosomal change in the telomere. Serial evaluation of telomere length is an indicator of how rapidly one ages relative to a normal population. Therapies directed at slowing the loss of telomere length may slow aging and age-related diseases.

Does diet have any effect on telomere length and repair?

An inflammatory diet, or one that increases oxidative stress, will shorten telomeres faster. This would include refined carbohydrates, fast foods, processed foods, sodas, artificial sweeteners, trans fats and saturated fats. A diet with a large amount and variety of antioxidants that improves oxidative defense and reduces oxidative stress will slow telomere shortening. Consumption of 10 servings of fresh and relatively uncooked fruits and vegetables, mixed fiber, monounsaturated fats, omega-3 fatty acids, cold water fish and high quality vegetable proteins can prevent premature shortening. In addition, caloric restriction is advised combined with an exercise program. Fasting for 12 hours each night at least 4 days per week may also be protective.

Aging CoupleWhat lifestyle modifications are likely to be helpful?

One should achieve ideal body weight and body composition with low body fat (less than 22 % for women and less than 16 % for men). Decreasing visceral fat is very important. Regular aerobic and resistance exercise for at least one hour per day, sleeping for at least 8 hours per night, stress reduction, discontinuation of all tobacco products and bioidentical hormone replacement therapy may decrease the rate of telomere loss.

Telomere AnalysisHow do you measure telomere length?

The Patient Telomere Score is calculated based on the patient’s telomere length on white blood cells (T-lymphocytes). This is the average compared to telomere length on lymphocytes from a sample of the American population in the same age range. The higher the telomere score, the “younger” the cells. A Telomere Score that is above the average line is desirable.

What can I do to reduce my rate of telomere loss?

Shorter telomeres have been associated with metabolic abnormalities, obesity and several degenerative diseases including cancer, dementia and cardiovascular disease. In vitro studies have shown that telomeres are highly susceptible to oxidative stress, which will shorten telomere length and enhance cellular aging. Minimizing associated risk factors that are linked to shortened telomere activity is recommended and include:

  • Reduce oxidative stress
  • Correct micronutrient deficiencies, especially vitamin D
  • Change sedentary lifestyle/ increase physical activity
  • Avoid weight gain or obesity
  • Correct insulin resistance

Studies have shown that telomere length is strongly associated with CVD risk, nutritional deficiencies (particularly antioxidants) and cancer and testing may be a useful biomarker for risk assessment.



Topics: SpectraCell, telomere length, Telomere testing, telomerase, diagnostic tools, telomere, health, telomere test, Aging, telomere and cancer

The Telomere Buzz is STILL Buzzing...

Posted by SpectraCell Laboratories, Inc. on Wed, May 18, 2011 @ 11:58 AM

SpectraCell Laboratories, the nation’s leading nutritional testing laboratory, offers a commercially available telomere analysis. Telomere testing is an innovative cellular aging test that measures a person’s biological age in comparison to their chronological age.

Telomere and ChromosomeTelomeres are sections of DNA at the end of each chromosome that cap genetic material and serve as protective buffers that keep the ends of chromosomes from becoming attached to each other or rearranging. They are often compared to the caps at the ends of shoelaces. Every time a cell replicates, its telomere gets shorter, eventually causing cell death once the telomere attrition has reach its maximum. Measuring telomere length in human lymphocytes is an indicator of cellular aging, and research demonstrates that shortened telomeres are responsible for many of the normal processes of aging.

“Telomeres have been a hot topic for several years now because their link with aging is so strong. Doctors have shown such a persistent interest in telomere testing, especially those whose practices are oriented to anti-aging, that we knew we should invest in it. It’s really cutting edge.” says SpectraCell CEO, William “Chip” Stanberry. “We strive to offer the most informative and innovative diagnostic tests, and our new Telomere Testing is exactly that.”

Telomere CapThe phenomenon of cellular aging was first noted by Professor Lenhard Hayflick in 1961. He discovered that cells cannot divide beyond a specific number of times, a phenomenon called the Hayflick Limit, which we now know is triggered by the cell’s telomeres shortening below a specific threshold. When cells can no longer divide, conditions associated with advanced aging appear.

Telomere length is affected by many factors: age, genetics, lifestyle, disease and pharmaceuticals. Chronic diseases such as cardiovascular disease, hypertension, diabetes, obesity and dementia have strong associations with shorter telomeres. But telomere attrition can be mitigated significantly with aggressive lifestyle therapies as well as certain medications. Since deficiencies in nutrients such as vitamins C, D and E can shorten telomeres, it is important to correct such deficiencies. Oxidative stress is another major culprit in telomere shortening so reducing inflammation and shoring up the body’s antioxidant defenses is critical for telomere maintenance. A sedentary lifestyle and excess weight also negatively affects telomere length.

Telomere ReportSpectraCell’s test measures a person’s telomere length. A control gene is also measured and compared to the telomere length, and then results are stated as a ratio. A higher ratio means a longer telomere, and younger biological age. The Telomere Score is also compared to other individuals in the same chronological age group.

This automated test is based on Quantitative Real Time PCR (polymerase chain reaction) technology and only requires 1 mL of whole blood. When a sample is received at SpectraCell’s Houston laboratory, the white blood cells are broken apart, the DNA is extracted and the telomeric DNA is amplified into a measurable signal. This signal is compared to a control gene of known length and a Telomere Score is generated.

The price of the Telomere Test is affordable and is also covered by insurance. Testing once each year or every other year is suggested to monitor the rate of telomere loss.

Are You a Physician? Become a client and offer Telomere Testing to your patients

Are You a Patient?  Use our 'Find a Clinician' search to find a doctor in your area today

Topics: SpectraCell, telomere length, Telomere testing, telomerase, diagnostic tools, telomere, health, Mortality, telomere test, telomere and cancer, Insurance

WEBINAR: Using Advanced Diagnostic Testing in a Concierge Practice

Posted by SpectraCell Laboratories, Inc. on Tue, Apr 12, 2011 @ 02:03 PM

WellnessRegister for our upcoming April 21st webinar on "Using Advanced Diagnostic Testing in a Concierge Practice" by Shelena C. Lalji, M.D.

Topics Discussed:

* Review of today's nutrient lacking foods

* Discuss the correlation between nutrient depletions and prescription medications

* Evaluation and implementation of diagnostic nutritional testing with medical grade supplements

* Detail the role of "8 Steps to Wellness" - providing patients complete health care with diagnostic tools including SpectraCell, BHRT and Allergy testing

* Explain how to incorporate all modalities in self-pay practice for optimal patient care and patient retention and referral

CLICK HERE to register for this webinar

Also, register for future webinars hosted by SpectraCell HERE.

Topics: micronutrient testing, diagnostic tools, wellness, supplements, Nutrition, deficiencies, Concierge Practice, webinar, Dr. Shelena Lalji