SpectraCell Blog

Vitamin A: Functions and Benefits

Posted by SpectraCell Laboratories, Inc. on Mon, Jul 31, 2017 @ 11:30 AM

vit A.jpgVitamin A was one of the earliest vitamins to be discovered – hence its top rank in the alphabetical vitamin nomenclature.Vitamin A is a family of fat soluble compounds that play an important role in vision, bone growth, reproduction, and immune system regulation. Most people associate vitamin A with carrots, and for good reason: the common orange veggie has high amounts of beta-carotene, which is actually a vitamin A precursor and also the reason carrots got their name. But vitamin A is actually a group of chemicals that are similar in structure, and include retinol (the most biologically active form of vitamin A), retinal, and retinoic acid.

β-carotene is slightly different in that it is cleaved in the intestinal mucosa by an enzyme to form retinol. Other carotenoids include lycopene and lutein but, although similar to vitamin A, they are not actually vitamin A in the truest sense. One distinction is that excessive amounts of vitamin A from over-supplementation, can cause toxicity (although deficiency is much more common). On the other hand, β-carotene does not cause vitamin A toxicity because there exists a regulatory mechanism that limits vitamin A production from beta carotene when high levels are ingested.

A large number of physiological systems may be affected by vitamin A deficiency which is most often associated with strict dietary restrictions and excess alcohol intake. Patients with Celiac disease, Crohn’s disease and pancreatic disorders are particularly susceptible due to malabsorption.  Vitamin A is also essential for the developing skeletal system and deficiency can result in growth retardation or abnormal bone formation. 

The functions of vitamin A are very diverse:

  • Eyesight: Vitamin A forms retinal, which combines with a protein (rhodopsin) to create the light-absorbing cells in the eye. This explains why a common clinical manifestation of deficiency is night blindness and poor vision.
  • Skin: In addition to promoting healthy skin function and integrity, vitamin A regulates the growth of epithelial surfaces in the eyes and respiratory, intestinal, and urinary tracts. Deficiency impairs epithelial regeneration, which can manifest as skin hyperkeratization, infertility, or increased susceptibility to respiratory infections.
  • Anemia: Vitamin A helps transfer iron to red blood cells for incorporation into hemoglobin; thus, a vitamin A deficiency will exacerbate an iron deficiency.
  • Weight management: Vitamin A reduces the size of fat cells, regulates the genetic expression of leptin (a hormone that suppresses appetite), and enhances the expression of genes that reduce a person’s tendency to store food as fat.
  • Cancer prevention: Vitamin A deficiency impairs the body’s ability to launch cell-mediated immune responses to cancer cells. Vitamin A inhibits squamous metaplasia (a type of skin cancer) and inhibits breast cancer cell growth.
  • Fertility: Vitamin A plays a key role in the synthesis of sperm.
  • Autism: Vitamin A is part of the retinoid receptor protein (G-alpha protein), which is critical for language processing, attention, and sensory perception. Some autistics have a defect in this protein that vitamin A supplementation can modulate.
  • Sleep: Vitamin A deficiency alters brains waves in non-REM sleep, causing sleep to be less restorative.

Vitamin A also interacts with other micronutrients. For example, zinc is required to transport vitamin A into tissues, so a zinc deficiency will limit retinal binding protein (RBP) synthesis and thus limits the body’s ability to use vitamin A stores in the liver. Oleic acid, a fatty acid found in olive oil, facilitates the absorption of vitamin A in the gut.

Find out if you have a vitamin A deficiency, and take steps to correct it, by ordering a micronutrient test today. 

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Topics: micronutrients, Vitamin A, Vitamins, Fertility, Cancer Prevention, Celiac Disease, Supernutrients, Weight Management, Vitamin A Deficiency, Chron's Disease, Anemia, Nutrients, β-carotene

Vitamin A - How does it AFFECT YOU!

Posted by SpectraCell Laboratories, Inc. on Thu, Aug 01, 2013 @ 11:47 AM

Vitamin A is a group of nutritionally unsaturated hydrocarbons. Different forms of the vitamin vitamin A include retinol, retinoic acid, and carotenoids. Retinol is the most biologically active form of vitamin A and is synthesized by pro-vitamin A(beta-carotene). Vitamin A regulates cell proliferation, differentiation, immune function and apoptosis (cell death).  This vitamin plays a vital role in night or low-light vision and color vision among many other common functions.

Symptoms of vitamin A deficiency - Impaired immune function; eye or skin problems; compromised cell growth and development; fat malabsorption; night blindness; zinc deficiency; insomnia.

Common conditions associated with vitamin A deficiency - Hormone balance, Immunidex, Insomnia, night blindness.

CASE STUDY highlights a common problem with a vitamin A deficiency. A 45 year old female with multiple conditions such as hypertension, insomnia and GERD, click here.

View our webinars Nutritional Considerations of Hormone Balance and Nutritional Considerations of Skin disorders, which references vitamin A deficiency among others in these conditions. 

To check your micronutrient levels or to get started click here

Topics: SpectraCell, micronutrients, micronutrient testing, Cancer, cancer cells, autoimmune diseases, zinc, Vitamin A, Migraines, Heart Disease, pregnancy, Multivitamins, immune system, E-zinc, breast cancer, Fertility, PMS, deficiencies, Case Study, Headache, Dr. Ron Grabowski, deficiency, Depression, degenerative illness, micronutrient test, Cancer Prevention, Hypothyroidism, Hormones, Menopause, HSVI, GERD, mitral valve prolapse, infertility, Immunidex, eczema and nutrition, Women's Health

Do the Prescriptions YOU take deplete your nutritional status?

Posted by SpectraCell Laboratories, Inc. on Wed, Jul 24, 2013 @ 03:34 PM

When a person takes prescription drugs or over the counter medication chances are that they can prescription depletions Page 1 resized 600 be affecting their nutrient levels. Below are some of the possible deficiencies that are correlated with each corresponding drug.

Antacids/Ulcer medications

  • vitamin B12 - Anemia, depression, tiredness, weakness, increased cardiovascular risk

  • Folic Acid - Birth defects, cervical dysplasia, anemia, heart disease, cancer risk

  • vitamin D - osteoporosis, muscle weakness, hearing loss

  • Calcium - Osteoporosis, heart and blood pressure irregularities, tooth decay

  • Iron - Anemia, weakness, fatigue, hair loss, brittle nails

  • Zinc - weak immunity, wound healing, sense of smell/taste, sexual dysfunction


Antibiotics

  • B vitamins, Vitamin K - short term depletion affects are minimal, but failure to re-inoculate the GI tract with beneficial bacteria (probiotics) often results in dysbiosis which causes gas, bloating, decreases digestion & absorption of nutrients, and also may lead to a variety of other health problems.

  • Calcium - osteoporosis, heart & blood pressure irregularities, tooth decay

  • magnesium - cardiovascular problems, asthma, osteoporosis, cramps, PMS

  • Iron - slow wound healing, fatigue, anemia

  • vitamin B6 - depression, sleep disturbance, increased cardiovascular disease risk

  • zinc - weak immunity, wound healing, sense of smell/taste, sexual dysfunction


Cholesterol drugs

  • Coenzyme Q10 - Various cardiovascular problems, weak immune system, low energy


Female Hormones

  • Vitamin B6 - depression, sleep disturbance, increased cardiovascular disease risk

  • Folic acid - birth defects, cervical dysplasia, anemia, cardiovascular disease

  • vitamin B1 - depression, irritability, memory loss, muscle weakness, edema

  • vitamin B2 - problems with skin, eyes, mucous membranes and nerves

  • vitamin B6 - depression, sleep disturbances, increased cardiovascular disease risk

  • vitamin B12 - anemia, depression, tiredness, weakness, increased cardiovascular risk

  • vitamin C - lowered immune system, easy bruising, poor wound healing

  • magnesium - cardiovascular problems, asthma, osteoporosis, cramps, PMS

  • selenium - lower immunity, reduced antioxidant protection'

  • zinc - weak immunity, wound healing, sense of smell/taste, sexual dysfunction


Anti-Inflammatories

  • calcium - osteoporosis, heart and blood pressure irregularities, tooth decay

  • vitamin D - osteoporosis, muscle weakness, hearing loss

  • magnesium - cardiovascular problems, asthma, osteoporosis, cramps, PMS

  • zinc - weak immunity, wound healing, sense of smell/taste, sexual dysfunction

  • vitamin C - lowered immunity, easy bruising, poor wound healing

  • vitamin B6 - depression, sleep disturbances,increased cardiovascular disease risk

  • vitamin B12 - anemia, depressioon, tiredness, weakness, increased cardiovascular risk

  • Folic Acid - birth defects, cervical dysplasia, anemia, cardiovascular disease

  • Selenium - lower immunity, reduced antioxidant protection

  • chromium - elevated blood sugar, cholesterol & triglycerides, diabetes risk

  • vitamin B5 - fatigue, listlessness, and possible problems with skin, liver and nerves

For a complete list of drugs and their correlating deficiencies click here

If you would like to check your nutrient levels click here

Topics: SpectraCell, micronutrients, Coenzyme Q10, Antidepressants, Cancer, autoimmune diseases, zinc, Vitamin D, Carnitine, Magnesium, Vitamin C, Vitamin E, Vitamin B6, B Vitamins, Folic Acid, Antioxidants, Fibromyalgia, Cholesterol, Cardiovascular Health, Heart Disease, Vitamin K, Vitamin B12, Chronic Disease, diabetes, immune system, E-zinc, Vitamins, Calcium, Fertility, PMS, deficiencies, chronic fatigue and nutrition, health, Inflammatory Bowel Disease, Depression, Diet, Digestion, Stress, Vitamin B1, micronutrient test, Inflammation, Vitamin B5, High Blood Pressure, Vitamin B2, Iron, Nutritional Deficiency, Cancer Prevention, Heart Health, Gastrointestinal Tract, Hypothyroidism, Allergies, Wound Healing, Vitamin B3, Antihistamines, cardiovascular disease, Nutrient, hypertension, Women's Health

Fertility Awareness Week - SpectraCell Female Fertility Chart

Posted by SpectraCell Laboratories, Inc. on Wed, Apr 24, 2013 @ 01:52 PM

Folate - Protects genes during rapid cell division which increases likelihood of a healthy 389 Female  Fertility Wheel 2.13 Page 1embryo (via methylation of DNA); Deficiency raises homocysteine which damages reproductive cells.

Vitamin B6  & B12 - Both are needed to convert toxic homocysteine to a benign form; Low homocysteine levels linked to a better chance of pregnancy.

Vitamin C - Increases serum progesterone levels; Induces ovulation in some women; Enhances effect of the fertility drug clomiphene.

Vitamin D - Higher levels linked to better success rates of IVF (in vitro fertilization); Influences production of the sex hormones estradiol and progesterone.

Vitamin E - Protects reproductive cells (follicles); May improve endometrial response (ability of fertilized egg to implant into uterine wall properly) during IVF.

Selenium - Deficiency implicated in miscarriage and infertility; In one trial, 100% of infertile women achieved pregnancy after supplemenation.

Glutathione - Protects eggs (fertilized or not) from damage by reactive oxygen species; Protective action of follicle stimulating hormone on embryonic development is due largely to glutathione synthesis.

Cysteine - N-acetyl cysteine can improve ovulation and pregnancy rates in women with infertility due to PCOS (polycystic ovary syndrome) that do not respond to fertility drugs; Improves viability of endometrial cells in vitro; Precurso to glutathione.

Antioxidant Status - Reproductive cells, including embryos, are very susceptible to damage from oxidative stress due to the rapid rate of growth; Low antioxidant status can cause infertility or miscarriage.

Minerals - Several enzymes needed to protect a woman's reproductive organs (such as superoxide dismutase) are dependent on the trace elements, zinc, copper and magnesium.

Click here to download your own copy of the Female Fertility Wheel

 

Topics: micronutrient testing, Cysteine, folate, Vitamin D, Vitamin C, Vitamin E, Selenium, Vitamin B6, B Vitamins, Antioxidants, Vitamin B12, Fertility, deficiencies, deficiency, Minerals

Theories, Research and Treatment with Vitamins and Antioxidants

Posted by SpectraCell Laboratories, Inc. on Thu, Mar 07, 2013 @ 09:31 AM

New theory on how vitamins work gains attention

A group of researchers in Europe proposed a new theory on how vitamins work in the body,vitamins displacing the former accepted view that vitamin molecules work directly on cells in the body. Their research, which used radiation and electron pulse technology, led them to conclude that antioxidant vitamins emit dissolved electrons that quench free radicals. They concluded that the well-known vitamin effects are attributed to “vitamin free radicals rather than the vitamin molecules per se, as generally accepted.”(Nutrition, January 2013)

Link to Abstract Vitamin-induced intracellular electrons are the mechanism for their well-known beneficial effects: A review.

Treatment resistant depression responds to folate therapy

Two randomized, double-blind trials were conducted in which depression, treatmentdepression patients who had a partial or no response to a SSRI (selective serotonin reuptake inhibitors) were given l-methylfolate for 60 days. In the first trial, the dosage of folate was 7.5mg/day for 30 days, then 15mg/day for 30 days. In the second trial, the dosage of folate was 15mg/day for 60 days. Patients in the second trial showed significantly greater efficacy of SSRI drugs (lower depression scores and significantly decreased symptom severity) compared to the first trial (where the dosage of folate was lower) and compared to placebo. (American Journal of Psychiatry, December 2012)

LINK to ABSTRACT  (L)-methylfolate as adjunctive therapy for SSRI-resistant major depression: results of two randomized, double-blind, parallel-sequential trial.
LINK to FLYER on NUTRIENT INTERACTIONS IN DEPRESSION

Antioxidant therapy benefits both anxiety and depression

Blood levels of the antioxidant (specifically, vitamins A, C and E) were measured in eighty patients ofantioxidant a psychiatric hospital that were diagnosed with stress-induced generalized anxiety disorder and depression. Supplements of each vitamin were given for six weeks and blood levels of each vitamin were measured again. After six weeks, blood levels of vitamin A and C had increased and there was a “significant reduction in anxiety and depression scores of patients.”(Indian Journal of Psychiatry, July2012)

LINK to ABSTRACT Role of antioxidants in generalised anxiety disorder and depression. 
LINK to FREE FULL TEXT
LINK to FLYER on NUTRIENT INTERACTIONS IN ANXIETY
LINK to FLYER on NUTRIENT INTERACTIONS IN DEPRESSION

Is B12 the magic bullet for hepatitis?

This paper concludes that B12 is particularly beneficial for hepatitis C viral therapy. Specifically, adding Vitamin B12vitamin B12 (5mg given intramuscularly every 4 weeks) to the conventional therapy of pegylated interferon plus ribavirin improved treatment response after 3 months. This confirms earlier research that shows vitamin B12 ca inhibit the hepatitis C virus in vitro.(Expert Review of Anti-Infective Therapy, November 2012)

LINK to ABSTRACT Vitamins? The magic bullet against hepatitis C.
LINK to FREE FULL TEXT

Vitamin D amplifies progesterone's neuroprotective effect after traumatic brain injury

Both progesterone and vitamin D have demonstrated neuroprotective effects on the brain after abrain injury traumatic injury in past studies, so a group of researchers sought to evaluate the effect of combining them. This randomized clinical trial compared progesterone treatment alone and combined with vitamin D to a placebo group and found that the “recovery rate of patients with severe brain trauma in the group receiving progesterone and vitamin D together was significantly higher than that of progesterone [only] group, which was in turn higher than that of placebo group.”(Advanced Biomedical Research, 2012)

LINK to ABSTRACT Comparison of the administration of progesterone versus progesterone and vitamin D in improvement of outcomes in patients with traumatic brain injury: A randomized clinical trial with placebo group.

Vitamin C help patients recover from hearing loss

72 patients with sudden hearing loss of unknown cause participated in this study. 36 patients served hearing lossas a control group that received steroid treatment for 15 days and 36 patients received the same steroid treatment plus high dose vitamin C intravenously daily for 10 days. Auditory evaluations were administered and the recovery rate of the group receiving vitamin C was more than twice that of the control group. (European Archives of Oto-rhino-laryngology, December 2012) 

LINK to ABSTRACT Effect of high dose intravenous vitamin C on idiopathic sudden sensorineural hearing loss: a prospective single-blind randomized controlled trial.

Mechanism behind serine's role for proper brain function is uncovered

Serine is a crucial amino acid needed to form proper synapses in the brain. It acts as abrain neurotransmitter and regulates NMDA(N-methyl-D-aspartate) receptors in the brain, which regulate mood and sleep, explaining its role in psychiatric and neurological disease. A recent study showed that serine supplementation could reverse oxidative stress-induced deficits in cognitive function.(Current Opinion in Clinical Nutrition and Metbolic Care, January 2013), (Aging Cell, April 2012), (Journal of Biological Chemistry, June 2012), (Biochemical Journal, 2003)

LINK to ABSTRACT D-Serine: physiology and pathology.
LINK to ABSTRACT Reversal of age-related oxidative stress prevents hippocampal synaptic plasticity deficits by protecting D-serine-dependent NMDA receptor activation.
LINK to ABSTRACT Resurgence of serine: an often neglected but indispensable amino acid.
LINK to ABSTRACT L-serine in disease and development. 
LINK to FREE FULL TEXT

For more educational resources visit our Clinical Education Center  

 

Topics: SpectraCell, Antidepressants, Autoimmunity, autoimmune diseases, folate, Vitamin D, Vitamin C, B Vitamins, Folic Acid, Antioxidants, Vitamin B12, immune system, Vitamins, Fertility, Case Study, Hearing, Depression, Brain, Hepatitis, anxiety

Vitamins, minerals and antioxidants can help!

Posted by SpectraCell Laboratories, Inc. on Thu, Jan 10, 2013 @ 01:20 PM

Is carnitine the answer for male infertility?male, infertility
A group of men (n=96) who had been diagnosed as infertile for at least 18 months were given the following nutritional formulation daily for four months: L-carnitine, acetyl-L-carnitine, fructose, citric acid, selenium, coenzyme Q10, zinc, vitamin C, vitamin B12 and folic acid (see abstract for exact dosages).  At the end of the study, sperm motility improved and 16 of the patients had achieved pregnancy.  The authors concluded that carnitine may be the key component of the supplement cocktail for improving sperm quality. (Italian Archives of Urology and Andrology, September 2012)

LINK to ABSTRACT Prospective open-label study on the efficacy and tolerability of a combination of nutritional supplements in primary infertile patients with idiopathic astenoteratozoospermia.

 

Vitamin D helps leg ulcers heal
In this double-blind, placebo controlled trial, 26 patients Vitamins, Vitamin Dwith leg ulcers were given either placebo or 50,000 IU vitamin D weekly for two months.  Leg ulcer size, blood levels of vitamin D and pain was measured before and after the two month trial.  In the vitamin D group, leg ulcers were reduced in size by 28% while the placebo group had only a 9% reduction in ulcer size. The authors stated “there was a trend toward better healing in those with vitamin D reposition.” (Journal of Brazilian College of Surgeons, October 2012)

LINK to ABSTRACT Vitamin D and skin repair: a prospective, double-blind and placebo controlled study in the healing of leg ulcers.
LINK to FREE FULL TEXT

 

Complexity of methylation reactions gains insightmethyl donor, nutrients
This review emphasizes how methyl donor nutrients such as choline, folic acid and methionine interact and how consumption (via supplement or food) of one can have sparing effect s on another – such as choline’s  sparing effect on methionine, for example. (Current Opinion in Clinical Nutrition and Metabolic Care, January 2013)

LINK to ABSTRACT The nutritional burden of methylation reactions.
LINK to FLYER on NUTRIENT INTERACTIONS in METHYLATION

For more journal articles by disease or nutrient please click here

 

Topics: SpectraCell, serine, micronutrients, Coenzyme Q10, Oleic Acid, Cysteine, autoimmune diseases, zinc, Vitamin D, Carnitine, Magnesium, Choline, Vitamin C, Vitamin E, Vitamin A, Selenium, Vitamin B6, B Vitamins, Folic Acid, Antioxidants, lipoprotein particle profile, Omega 3 Fatty Acid, diagnostic tools, vitamin, wellness, pregnancy, Serum, Vitamin K, Vitamin B12, supplements, Multivitamins, Nutrition, diabetes, immune system, E-zinc, N-acetylcysteine, DNA, Calcium, Fertility, Lipoic Acid, deficiencies, health, Case Study, Omega 3s, Depression, Glutamine, Minerals, Neurotransmitters, Stress, Vitamin B1, micronutrient test, Vitamin B5, Vitamin B2, Nutritional Deficiency, Vitamin B3, cardiovascular disease, Hormones, Reproductive Health, Chromium, Manganese, Muscle recovery, Erectile Dysfunction, infertility, Niacin, Prostate, Energy, Methylation, Carbohydrate Metabolism

SpectraCell's Clinical Updates - Volume 6, Issue 7

Posted by SpectraCell Laboratories, Inc. on Thu, Aug 09, 2012 @ 10:37 AM

Omega 3sCLINICAL UPDATE - Omega 3s Can Replace Ibuprofen for PMS Pain
In this trial, a group of women were given either placebo or omega3 fatty acids for three months, followed by three months of the opposite regimen.  Symptoms of PMS, especially pain, were monitored. After 3 months of treatment, women who took the omega 3 capsules every day decreased their ibuprofen usage by 19% (first group) and by 53% (second group). (International Journal of Gynaecology and Obstetrics, April 2012)

LINK to ABSTRACT  Effect of omega-3 fatty acids on intensity of primary dysmenorrhea

AsthmaticsCLINICAL UPDATE - Carnitine Supplements Improve Lung Function in Asthmatics
A recent placebo-controlled study compared 50 children with asthma to 50 healthy controls and found that not only were levels of the amino acid carnitine lower in those with asthma, but supplementation with 350mg of L-carnitine daily for six months significantly improved lung function is those with asthma.   Researchers noted that carnitine’s primary role in transporting fatty acids into the mitochondria may explain its benefit to those with asthma – carnitine also transports fatty acids to lung membrane surfaces ensuring they are lubricated, explaining a mechanism by which carnitine improves pulmonary function. (Journal of Allergy, 2012)

LINK to ABSTRACT L-carnitine improves the asthma control in children with moderate persistent asthma.
LINK to FREE FULL TEXT
LINK to FLYER on NUTRIENT INTERACTIONS OF ASTHMA

DiabetesCLINICAL UPDATE - Vitamin C Benefits Diabetics on Metformin
Seventy patients with type II diabetes were given either placebo or 500mg vitamin C twice a day.  All patients were taking metformin as well. After twelve weeks, measures of blood sugar control (fasting blood sugar, post-meal blood glucose and HbA1c levels) were all improved in the vitamin C group only. (Advances in Pharmalogical Sciences, 2011)

LINK to ABSTRACT Supplementation of vitamin C reduces blood glucose and improves glycosylated hemoglobin in type 2 diabetes mellitus: a randomized, double-blind study.
LINK to FREE FULL TEXT

Brain InjuryCLINICAL UPDATE - Zinc: A New Role for Traumatic Brain Injury
In this review, the protective role of zinc against traumatic brain injury is elucidated.  The authors stat that human clinical data “suggest that zinc may increase resilience” and can be used “to improve cognitive and behavioural deficits associated with brain injury.” (Nutrition Reviews, July 2012)

LINK to ABSTRACT Improving treatments and outcomes: an emerging role for zinc in traumatic brain injury.

FertilityCLINICAL UPDATE - Vitamin E Increases Sperm Count
106 infertile men were included in this trial  – 64 were infertile due to low sperm count and 42 were infertile due to poor sperm motility.  They were divided into two groups – both groups received pharmaceutical therapy for fertility but only one group was simultaneously treated with a natural form of vitamin E.  Sperm count and motility improved more dramatically in the vitamin E treated group.  In fact, only five natural pregnancies occurred in the non-vitamin E group, while 15 natural pregnancies occurred in the vitamin E treated group.  In an unrelated trial, vitamin E was co-administered with fertility drugs to a group of women and compared to fertility drug treated women without vitamin E.  Although those treated with vitamin E did not have statistically higher rates of pregnancy, the women given vitamin E did show significantly improved endometrial thickness, which would facilitate future pregnancy. (Natural Journal of Andrology, May 2012; Journal of Assisted Reproduction and Genetics, April 2012)

LINK to ABSTRACT Efficacy of natural vitamin E on oligospermia and athenospermia: a prospective multi-centered randomized controlled study of 106 cases.
LINK to ABSTRACT Vitamin E effect on controlled ovarian stimulation of unexplained infertile women.

Muscle MassCLINICAL UPDATE - A New Role for Omega 3s in Building Muscle Mass
A group of women (average age = 64 years old) were put on a strength training program for 90 days.  Some of the women were given fish oil supplements while others received no supplement. Measures of muscle strength were taken and those taking fish oil showed significantly higher muscle development.  Researchers hypothesized that this increase in muscle development during strength training is due to the role omega 3 fatty acids play in plasma membranes and muscle cell function. (American Journal of Clinical Nutrition, February 2012)

LINK to ABSTRACT Fish-oil supplementation enhances the effects of strength training in elderly women.

SerineCLINICAL UPDATE - High Dose Serine Improves Neuropathy: Case Report
One of the most common inherited neurological disorders, Charcot-Marie-Tooth disease affects approximately 1 in every 2500 people and is characterized by muscle wasting and peripheral neuropathy. In this case report, a male patient with polyneuropathy had a serine synthesis defect.  Deficiency in the amino acid serine often manifests neurologically and in this case, high-dose supplementation of serine improved his neuropathy symptoms. (Archives of Neurology, March 2012)

LINK to ABSTRACT A Serine Synthesis Defect Presenting With a Charcot-Marie-Tooth-Like Polyneuropathy.

Clicke HERE to browse our archived library of clinical updates

Topics: serine, zinc, Carnitine, Vitamin C, Vitamin E, diabetes, Fertility, PMS, Omega 3s, Asthma

Case Study: 25 Year Old Female with History of Infertility

Posted by SpectraCell Laboratories, Inc. on Tue, Jun 12, 2012 @ 10:16 AM

MotherPreviously treated for ogilomenorrhea, acne, menorrhaggia, cold intolerance, obesity with gradual weight gain and Polycystic Ovarian Syndrome

In September 2003, the patient was very interested in becoming pregnant. She was counseled in and utilized Basal Body Temperature charting with adjunctive use of the LH ovulation kit. She and her husband were counseled on focused sex for five days before and three days after ovulation. After more than a year and a half of unsuccessful attempts at pregnancy, the physician performed SpectraCell’s micronutrient testing in June 2005. Her results returned gross deficiencies of vitamins B1 (Thiamin), B6 (Pyridoxine) and E (alpha-tocopherol). She was also grossly deficient in Zinc, Serine, Glutamine and Coenzyme Q10 in addition to revealing a Glucose-Insulin interaction consistent with insulin resistence frequently found in PCOS. Her Antioxidant Function was remarkably low at 38.1% demonstrating increased potential for oxidative damage. All of the abnormalities were present despite the patient taking excellent prenatal vitamins, fish oil, chromium and NAC. Based upon her deficiencies found with SpectraCell’s micronutrient testing, she was placed on adequate replacement for each of the gross and even the marginal deficiencies in June 2005.


PregnancyClinical Outcome:
She and her husband subsequently became pregnant very quickly within a month and she attended her first obstetrics appointment on August 2005. She delivered a 8lb. 7oz. viable baby boy at 38 and a half weeks by vaginal delivery after being induced for mild preeclampsia.


Conclusion:
As a result of performing SpectraCell’s micronutrient testing, her physician was able to identify key nutritional deficiencies in this patient which occurred despite the patient following a good diet and taking good prenatal vitamins and other nutritional supplements. Her physician safely supplemented her during her pregnancy knowing that the patient and thus the baby did in fact need these nutrients. This helped allay fears of over supplementation and facilitated optimal growth and development of what proved toFertility become an extremely healthy and happy young male child.


Approximately 85% of women will become pregnant within one year of trying. This young lady had been unsuccessful for 21 months before her nutritional deficiencies were identified and supplemented and then became pregnant shortly thereafter. She would have probably had to undergo fertility treatment as do many women with PCOS. The 27 year old white female with PCOS and infertility is forever grateful for the existence and utilization of SpectraCell’s micronutrient testing.

Interested in learning more about women's health and infertility?


Topics: SpectraCell, micronutrient testing, Fertility

A SUCCESSFUL Case Study Involving Infertility and Nutritional Status

Posted by Heather Vorce on Mon, Jul 19, 2010 @ 12:36 PM

woman, health infertilityA 25 year old white female was dealing with prolonged infertility issues. She was also previously treated for Polycystic Ovarian Syndrome)

Case Summary:
In September 2003, this patient was very interested in becoming pregnant. She utilized Basal Body Temperature charting with adjunctive use of the LH ovulation kit. She and her husband were counseled on focused sex for five days before and three days after ovulation. After more than a year and a half of unsuccessful attempts at pregnancy, her physician recommended SpectraCell’s micronutrient testing. Almost two years later, her results returned gross deficiencies of:

  • Vitamin B1 (Thiamine)
  • Vitamin B6 (Pyridoxine)
  • Vitamin E (alpha-tocopherol)
  • Zinc
  • Serine
  • Glutamine
  • Coenzyme Q10
  • Glucose-Insulin interaction (consistent with insulin resistence frequently found in PCOS).
Her Antioxidant Function was remarkably low at 38.1% demonstrating increased potential for oxidative damage. All of the abnormalities were present despite her taking excellent prenatal vitamins, fish oil, chromium and NAC.

Based upon her deficiencies found with SpectraCell’s micronutrient testing, she was recommended adequate replacement for each of the deficiencies.

child, health, infertilityClinical Outcome:
She and her husband subsequently became pregnant very quickly (within a month) and attended her first obstetrics appointment. She delivered a 8lb. 7oz. viable baby boy at 38 and a half weeks by vaginal delivery.


Conclusion:
As a result of performing SpectraCell’s micronutrient testing, the physician was able to identify key nutritional deficiencies in their patient which occurred despite the patient following a good diet and taking good prenatal vitamins and other nutritional supplements.

The physician was also able to safely supplement her during her pregnancy which helped facilitate optimal growth and development of an extremely healthy and happy baby.

Infertility, fertility, children, women's healthApproximatley 85% of women will become pregnant within one year of trying. This young lady had been unsuccessful for 21 months. If she had not become pregnant, she probably would have used fertility treatments, as do many women with PCOS. This patient is forever grateful for the existence and utilization of SpectraCell’s micronutrient testing.

 

If you or someone you know has had trouble conceiving, what have they tried?  Have the been successful?

Topics: SpectraCell, Nutrition, Fertility, infertility, Women's Health