SpectraCell Blog

The Role of Nutrition in Hormonal Health

Posted by SpectraCell Laboratories, Inc. on Fri, Jan 09, 2015 @ 10:57 AM

Hormone Balance Logo resized 600Micronutrients profoundly affect hormonal health.  It is difficult to achieve hormonal balance if micronutrient status is inadequate, and like nutrients, hormones affect cellular metabolism, energy production, detoxification efficiency and mental health so balance is Key. 

Like nutrients, hormones influence all aspects of health and disease - mood, sleep, metabolism, immunity, heart health and appearance.  An imbalance of one hormone can initiate a cascade of events that alters other hormones.  
  • Fatigue & Energy Levels
  • Cardiovascular health (Blood pressure, clotting, lipids)
  • Neurology (migraines, sleep, pain)
  • Mental Health (depression, anxiety, cognitive function)
  • Immunity (infections, autoimmune disease)
  • Metabolism (blood sugar regulation, tissue repair)
  • Bone density (Osteoporosis)
  • Physical appearance (skin, muscles, hair)
SpectraCell Laboratories offers comprehensive male and female hormone panels that reveal the overall state of hormonal balance in a patient.

A comprehensive look at your hormone status is key.

GET TESTED!

Topics: SpectraCell, Vitamins, micronutrient, Hypothyroidism, Hormones, Menopause, infertility, Women's Health

Vitamin A - How does it AFFECT YOU!

Posted by SpectraCell Laboratories, Inc. on Thu, Aug 01, 2013 @ 11:47 AM

Vitamin A is a group of nutritionally unsaturated hydrocarbons. Different forms of the vitamin vitamin A include retinol, retinoic acid, and carotenoids. Retinol is the most biologically active form of vitamin A and is synthesized by pro-vitamin A(beta-carotene). Vitamin A regulates cell proliferation, differentiation, immune function and apoptosis (cell death).  This vitamin plays a vital role in night or low-light vision and color vision among many other common functions.

Symptoms of vitamin A deficiency - Impaired immune function; eye or skin problems; compromised cell growth and development; fat malabsorption; night blindness; zinc deficiency; insomnia.

Common conditions associated with vitamin A deficiency - Hormone balance, Immunidex, Insomnia, night blindness.

CASE STUDY highlights a common problem with a vitamin A deficiency. A 45 year old female with multiple conditions such as hypertension, insomnia and GERD, click here.

View our webinars Nutritional Considerations of Hormone Balance and Nutritional Considerations of Skin disorders, which references vitamin A deficiency among others in these conditions. 

To check your micronutrient levels or to get started click here

Topics: SpectraCell, micronutrients, micronutrient testing, Cancer, cancer cells, autoimmune diseases, zinc, Vitamin A, Migraines, Heart Disease, pregnancy, Multivitamins, immune system, E-zinc, breast cancer, Fertility, PMS, deficiencies, Case Study, Headache, Dr. Ron Grabowski, deficiency, Depression, degenerative illness, micronutrient test, Cancer Prevention, Hypothyroidism, Hormones, Menopause, HSVI, GERD, mitral valve prolapse, infertility, Immunidex, eczema and nutrition, Women's Health

Studies Show How Micronutrients can Help

Posted by SpectraCell Laboratories, Inc. on Thu, Apr 11, 2013 @ 03:04 PM

Vitamin D protects telomeres: a randomized, controlled trialTelomeres

Telomerase activity was measured before and after 37 people were given either placebo or about 2000IU of oral vitamin D supplements per day for 16 weeks.  Serum vitamin D levels for those taking the supplement increased almost 200%.  The telomerase activity increased over 19% as well, while the telomerase activity of those on placebo did not change. (International Journal of Obesity, June 2012)

LINK to ABSTRACT Increased telomerase activity and vitamin D supplementation in overweight African Americans.
LINK to FLYER ON NUTRIENT INTERACTIONS WITH TELOMERES

Vitamin C helps antidepressant drug work better
Vitamin C In this randomized, double-blind, placebo controlled trial, a group of patients with major depressive disorder (n=12) were given fluoxetine plus 1000mg of vitamin C daily and compared to a group (n=12) that were given fluoxetine plus placebo.  After six months, those receiving vitamin C in conjunction with fluoxetine showed a significant decrease in symptoms when evaluated using three different standardized depression rating systems compared to the placebo group. (Nutrition Journal, March 2013)

LINK to ABSTRACT Efficacy of vitamin C as an adjunct to fluoxetine therapy in pediatric major depressive disorder: a randomized, double-blind, placebo-controlled pilot study.
LINK to FREE FULL TEXT
LINK to FLYER ON NUTRIENT INTERACTIONS IN DEPRESSION

Serine improves ADHD symptoms
serine resized 600In this randomized, double-blind trial, 36 children diagnosed with ADHD received either 200mg of phosphatidylserine or placebo daily for two months.  Those receiving phosphatidylserine showed improved memory, attention and control of impulses compared to placebo.  Serine’s key role in psychiatric and neurological health has been gaining attention from studies such as this.  The authors concluded that phosphatidylserine “may be a safe and natural nutritional strategy for improving mental performance.”
(Journal of Human Nutrition and Dietetics, March 2013)

LINK to ABSTRACT The effect of phosphatidylserine administration on memory and symptoms of attention-deficit hyperactivity disorder: a randomised, double-blind, placebo-controlled clinical trial.
LINK to FLYER ON NUTRIENT INTERACTIONS IN ADHD

Are micronutrients underrated when it comes to pregnancy chances in assisted reproduction?
pregnancy resized 600Several recent studies are suggesting that micronutrient status prior to and during pregnancy should get more attention.  One study showed that low blood values of B vitamins and high homocysteine in mid pregnancy reduced fetal growth rates.  Another study showed that low homocysteine, determined by B vitamin status, was linked to a better chance of pregnancy in women undergoing assisted reproduction.  Yet another study showed that subfertile women undergoing ovulation induction who were taking a multi-micronutrient vitamin were more likely to get pregnant than women who took only a folic acid supplement.  Finally, a recently published review demonstrates how increasing a woman’s ability to fight oxidative stress increases her chances of successful pregnancy via assisted reproduction.
(Maternal of Child Nutrition, April 2013)
(Journal of Assisted Reproduction and Genetics, April 2012)
(Reproductive Biomedicine Online, January 2012)
(Reproductive Biology and Endocrinology, June 2012)

LINK to ABSTRACT Folate, Vitamin B12, Vitamin B6 and homocysteine: impact on pregnancy outcome.
LINK to ABSTRACT
The association between homocysteine in the follicular fluid with embryo quality and pregnancy rate in assisted reproductive techniques.
LINK to ABSTRACT Prospective randomized trial of multiple micronutrients in subfertile women undergoing ovulation induction: a pilot study.
LINK to ABSTRACT The effects of oxidative stress on female reproduction: a review.
LINK to FREE FULL TEXT
LINK to FLYER ON NUTRIENT INTERACTIONS IN FEMALE FERTILITY

Study sheds light on CoQ10’s role in healthy spermsperm resized 600
Sixty infertile men were given 200mg of CoQ10 or placebo for 3 months.  CoQ10 lowered oxidative stress in semen (measured by isoprostanes and superoxide dismutase activity) and improved sperm function significantly. (Andrologia, January 2013)

LINK to ABSTRACT Effect of Coenzyme Q10 supplementation on antioxidant enzymes activity and oxidative stress of seminal plasma: a double-blind randomised clinical trial.

 

For more information on micronutrients and telomeres CLICK HERE

 

Topics: SpectraCell, serine, micronutrients, Coenzyme Q10, Antidepressants, Vitamin D, Vitamin C, Telomere testing, telomere, deficiency, micronutrient test, ADHD, Nutritional Deficiency, Heart Health, Nutrient, telomere test, Hormones, Aging, Reproductive Health, infertility, Testosterone, Women's Health

Vitamins, minerals and antioxidants can help!

Posted by SpectraCell Laboratories, Inc. on Thu, Jan 10, 2013 @ 01:20 PM

Is carnitine the answer for male infertility?male, infertility
A group of men (n=96) who had been diagnosed as infertile for at least 18 months were given the following nutritional formulation daily for four months: L-carnitine, acetyl-L-carnitine, fructose, citric acid, selenium, coenzyme Q10, zinc, vitamin C, vitamin B12 and folic acid (see abstract for exact dosages).  At the end of the study, sperm motility improved and 16 of the patients had achieved pregnancy.  The authors concluded that carnitine may be the key component of the supplement cocktail for improving sperm quality. (Italian Archives of Urology and Andrology, September 2012)

LINK to ABSTRACT Prospective open-label study on the efficacy and tolerability of a combination of nutritional supplements in primary infertile patients with idiopathic astenoteratozoospermia.

 

Vitamin D helps leg ulcers heal
In this double-blind, placebo controlled trial, 26 patients Vitamins, Vitamin Dwith leg ulcers were given either placebo or 50,000 IU vitamin D weekly for two months.  Leg ulcer size, blood levels of vitamin D and pain was measured before and after the two month trial.  In the vitamin D group, leg ulcers were reduced in size by 28% while the placebo group had only a 9% reduction in ulcer size. The authors stated “there was a trend toward better healing in those with vitamin D reposition.” (Journal of Brazilian College of Surgeons, October 2012)

LINK to ABSTRACT Vitamin D and skin repair: a prospective, double-blind and placebo controlled study in the healing of leg ulcers.
LINK to FREE FULL TEXT

 

Complexity of methylation reactions gains insightmethyl donor, nutrients
This review emphasizes how methyl donor nutrients such as choline, folic acid and methionine interact and how consumption (via supplement or food) of one can have sparing effect s on another – such as choline’s  sparing effect on methionine, for example. (Current Opinion in Clinical Nutrition and Metabolic Care, January 2013)

LINK to ABSTRACT The nutritional burden of methylation reactions.
LINK to FLYER on NUTRIENT INTERACTIONS in METHYLATION

For more journal articles by disease or nutrient please click here

 

Topics: SpectraCell, serine, micronutrients, Coenzyme Q10, Oleic Acid, Cysteine, autoimmune diseases, zinc, Vitamin D, Carnitine, Magnesium, Choline, Vitamin C, Vitamin E, Vitamin A, Selenium, Vitamin B6, B Vitamins, Folic Acid, Antioxidants, lipoprotein particle profile, Omega 3 Fatty Acid, diagnostic tools, vitamin, wellness, pregnancy, Serum, Vitamin K, Vitamin B12, supplements, Multivitamins, Nutrition, diabetes, immune system, E-zinc, N-acetylcysteine, DNA, Calcium, Fertility, Lipoic Acid, deficiencies, health, Case Study, Omega 3s, Depression, Glutamine, Minerals, Neurotransmitters, Stress, Vitamin B1, micronutrient test, Vitamin B5, Vitamin B2, Nutritional Deficiency, Vitamin B3, cardiovascular disease, Hormones, Reproductive Health, Chromium, Manganese, Muscle recovery, Erectile Dysfunction, infertility, Niacin, Prostate, Energy, Methylation, Carbohydrate Metabolism

SpectraCell's Clinical Updates - Volume 6, Issue 4

Posted by SpectraCell Laboratories, Inc. on Mon, May 07, 2012 @ 11:59 AM

VitaminsCLINICAL UPDATE - SELENIUM: KNOW IF YOU HAVE TOO MUCH OF A GOOD THING
An exhaustive review of the benefits selenium has on human health emphasizes that there is a definite “U-shaped link with status.”  The paper epitomizes the philosophy that more-is-not-always-better for vitamins and minerals.  Although low selenium status has been linked to several diseases – heart disease, infertility, low immunity, poor cognitive function, thyroid disease and cancer – the authors state that although “additional selenium intake may benefit individuals with low status, those with adequate status might be affected adversely and should not take selenium supplements.”  (Lancet, March 2012)

LINK to ABSTRACT Selenium and human health.

Heavy Metal ToxicityCLINICAL UPDATE - NUTRIENT DEFICIENCY CAUSING HEAVY METAL TOXICITY?
A case study on a 37 year old man suggests that multiple micronutrient deficiencies played a role in the cause of his multiple sclerosis.  The authors state he had several key nutrient deficiencies, which they think impaired his ability to excrete harmful metals.  They sate that “nutritional treatment may be an effective approach to this disease” due to the role of nutrients in various detoxification pathways. (Current Aging Science, Epub ahead of print in August 2011)

LINK to ABSTRACT Influence of Essential Trace Minerals and Micronutrient Insufficiencies on Harmful Metal Overload in a Mongolian Patient with Multiple Sclerosis.
 
Blood PressureCLINICAL UPDATE - META-ANALYSIS FINDS VITAMIN C SUPPLEMENTS LOWER BLOOD PRESSURE
In a review of 29 randomized controlled trials of oral vitamin C, authors found that vitamin C supplements reduced both systolic and diastolic blood pressure.  The reduction in blood pressure was more pronounced in people with existing hypertension.  In another meta-analysis, magnesium supplementation also lowered blood pressure. (American Journal of Clinical Nutrition, May 2012; European Journal of Clinical Nutrition, April 2012)

LINK to ABSTRACT Effects of vitamin C supplementation on blood pressure: a meta-analysis of randomized controlled trials.
LINK to ABSTRACT Effect of magnesium supplementation on blood pressure: a meta-analysis.

Oxidative Stress and HypothyroidismCLINICAL UPDATE - FOLIC ACID LOWERS OXIDATIVE STRESS IN HYPOTHYROIDISM
In two separate studies, antioxidant function was evaluated after hypothyroidism was induced.  Since basal metabolic rate is lower in hypothyroism and most oxidative stress in the body stems from basic metabolic functions, some researchers hypothesize that hypothyroidism should result in lower levels of oxidative stress.  But in this recent animal study, the authors found higher levels of oxidative stress in the hypothyroid (vs normal thyroid) state, as well as higher levels of homocysteine.  Treatment with folic acid ameliorated these effects.  In another study, authors found that hypothyroidism reduced antioxidant function, although the serum levels of several antioxidants. (vitamins A, C & E) remained constant. (Toxicology and Industrial Health, April 2012; Endokrynologia Polska, 2011)

LINK to ABSTRACT
The effect of folic acid as an antioxidant on the hypothalamic monoamines in experimentally induced hypothyroid rat.
LINK to ABSTRACT Elements of oxidation/reduction balance in experimental hypothyroidism.
LINK to FREE FULL TEXT
LINK to NUTRIENT INTERACTION CHART FOR HYPOTHYROIDISM

ToxicityCLINICAL UPDATE - COQ10 PROTECTS LIVER FROM ACETAMINOPHEN TOXICITY
A single toxic dose of acetaminophen was administered in an animal study and liver damage was monitored.  After 1 hour and after 12 hours, an injection of coenzyme Q10 was given. The results showed that the coQ10 injections protected the liver from acetaminophen-induced damage.  The coQ10 also attenuated the loss of zinc and selenium that occurred after acetaminophen administration. (Environmental Toxicology and Pharmacology, March 2012)

LINK to ABSTRACT Hepatoprotective effect of coenzyme Q10 in rats with acetaminophen toxicity.

Infertility and Vitamin ECLINICAL UPDATE - VITAMIN E MAY HELP INFERTILE WOMEN
103 women with unexplained infertility were divided into two groups – 50 women were given a drug to induce ovulation (clomiphene citrate) combined with 400IU per day of vitamin E and 53 women were induced to ovulate without the administration of vitamin E.  The supplemented group had a significantly thicker endometrium and authors suggest that vitamin E may be beneficial to women with unexplained infertility by improving the “endometrial response” and that it may “modulate the antiestrogenic effect of clomiphene citrate.” (Journal of Assisted Reproduction and Genetics, February 2012)

LINK to ABSTRACT Vitamin E effect on controlled ovarian stimulation of unexplained infertile women.

Carbohydrate MetabolismCLINICAL UPDATE - BIOTIN DEFICIENCY IMPAIRS CARBOHYDRATE METABOLISM
Researchers found that biotin deficiency negatively alters carbohydrate metabolism.  Specifically, biotin deficiency resulted in an impaired glucose and insulin tolerance test, suggesting “defects in insulin sensitivity,” according to the authors. (Journal of Nutritional Biochemistry, April 2012)

LINK to ABSTRACT Effects of biotin deficiency on pancreatic islet morphology, insulin sensitivity and glucose homeostasis.

Read more of our clinical updates in our archive!

 

Topics: Coenzyme Q10, Vitamin C, Vitamin E, Selenium, Folic Acid, biotin, Hypothyroidism, Oxidative Stress, infertility, Carbohydrate Metabolism, Blood Pressure, Heavy Metal Toxicity

A SUCCESSFUL Case Study Involving Infertility and Nutritional Status

Posted by Heather Vorce on Mon, Jul 19, 2010 @ 12:36 PM

woman, health infertilityA 25 year old white female was dealing with prolonged infertility issues. She was also previously treated for Polycystic Ovarian Syndrome)

Case Summary:
In September 2003, this patient was very interested in becoming pregnant. She utilized Basal Body Temperature charting with adjunctive use of the LH ovulation kit. She and her husband were counseled on focused sex for five days before and three days after ovulation. After more than a year and a half of unsuccessful attempts at pregnancy, her physician recommended SpectraCell’s micronutrient testing. Almost two years later, her results returned gross deficiencies of:

  • Vitamin B1 (Thiamine)
  • Vitamin B6 (Pyridoxine)
  • Vitamin E (alpha-tocopherol)
  • Zinc
  • Serine
  • Glutamine
  • Coenzyme Q10
  • Glucose-Insulin interaction (consistent with insulin resistence frequently found in PCOS).
Her Antioxidant Function was remarkably low at 38.1% demonstrating increased potential for oxidative damage. All of the abnormalities were present despite her taking excellent prenatal vitamins, fish oil, chromium and NAC.

Based upon her deficiencies found with SpectraCell’s micronutrient testing, she was recommended adequate replacement for each of the deficiencies.

child, health, infertilityClinical Outcome:
She and her husband subsequently became pregnant very quickly (within a month) and attended her first obstetrics appointment. She delivered a 8lb. 7oz. viable baby boy at 38 and a half weeks by vaginal delivery.


Conclusion:
As a result of performing SpectraCell’s micronutrient testing, the physician was able to identify key nutritional deficiencies in their patient which occurred despite the patient following a good diet and taking good prenatal vitamins and other nutritional supplements.

The physician was also able to safely supplement her during her pregnancy which helped facilitate optimal growth and development of an extremely healthy and happy baby.

Infertility, fertility, children, women's healthApproximatley 85% of women will become pregnant within one year of trying. This young lady had been unsuccessful for 21 months. If she had not become pregnant, she probably would have used fertility treatments, as do many women with PCOS. This patient is forever grateful for the existence and utilization of SpectraCell’s micronutrient testing.

 

If you or someone you know has had trouble conceiving, what have they tried?  Have the been successful?

Topics: SpectraCell, Nutrition, Fertility, infertility, Women's Health