SpectraCell Blog

SpectraCell's Nutritional Correlation Chart on Autism

Posted by SpectraCell Laboratories, Inc. on Wed, Feb 06, 2013 @ 01:54 PM

Autism Nutritional WheelVitamin D - High dose vitamin D therapy reversed autistic behaviors in severely deficient children; Maternal vitamin D deficiency may predispose children to autism.3,4,5

Vitamin A - One cause of autism may be a defect in a retinoid receptor protein (G-alpha protein) which is critical for language processing, attention and sensory perception; Evidence suggests natural vitamin A fixes this protein defect in autistics.1,2

Folate - Oral folate therapy can resolve symptoms of autism in some cases, particularly in autistics with genes that impair folate dependent enzymes.31,32,33

Glutamine - Blood levels of this amino acid which acts as a neurotransmitter are particularly low in autistics. Glutamine also helps prevent leaky gut syndrome, which can exacerbate autistic symptoms.28,29,30

Vitamin C - Improved symptom severity and sensory motor scores in autistic patients possibly due to interaction with dopamine synthesis; Vitamin C also has a strong sparing effect on glutathione.26,27

Glutathione & Cysteine -  Commonly deficient in autistic patients, lack of these antioxidants impair detoxification and methylation processes; Low levels linked to neurological symptoms in autism which is often considered an oxidative stress disorder.21,22,23,24,25

Vitamin B1 - Deficiency linked to delayed language development; Supplementation may benefit autistic patients.19,20

Vitamin B12 - Low B12 impairs methylation (detoxification) which causes the neurological damage responsible for many autistic symptoms; Deficiency of B12 can cause optic neuropathy and vision loss in autistics; B12 raises cysteine and glutathione levels.16,17,18

Vitamin B6 - Cofactor the neurotransmitters serotonin and dopamine; Conversion of B6 to its active form is compromised in many autistics; Supplementation trials with B6 resulted in better eye contact, speech and fewer self-stimulatory behavior in autistics; Some consider B6 in combination with magnesium to be a breakthrough treatment for autism.14,15

Magnesium - Cofactor for the neurotransmitters that affect social reactions and emotion; Autistics have low levels; Improves effectiveness of B6 therapy.11,12,13

Zinc - Eliminates toxic mercury from brain tissue; Zinc/ copper ratio is particularly low in autistic kids; Low zinc impairs  the protein (called metallothionein) that removes heavy metals from the body.8,9,10

Carnitine - Transports fatty acids into cells; Low carnitine (common in autism) impairs the ability to use fatty acids for learning and social development.6,7

 For a copy of Spectracell's Nutrition Correlation chart on Autism click here

Topics: micronutrients, micronutrient testing, Cysteine, Antidepressants, zinc, folate, Vitamin D, Carnitine, Magnesium, Vitamin C, Vitamin A, Vitamin B6, B Vitamins, Antioxidants, diagnostic tools, supplements, autism, Vitamins, DNA, deficiencies, health, deficiency, Depression, Glutamine, Neurology, Glutathione, Diet, Minerals, Digestion, Brain, Nervous System, Neurotransmitters, Aggression, Stress, Vitamin B1, degenerative illness, micronutrient test

Vitamins, minerals and antioxidants can help!

Posted by SpectraCell Laboratories, Inc. on Thu, Jan 10, 2013 @ 01:20 PM

Is carnitine the answer for male infertility?male, infertility
A group of men (n=96) who had been diagnosed as infertile for at least 18 months were given the following nutritional formulation daily for four months: L-carnitine, acetyl-L-carnitine, fructose, citric acid, selenium, coenzyme Q10, zinc, vitamin C, vitamin B12 and folic acid (see abstract for exact dosages).  At the end of the study, sperm motility improved and 16 of the patients had achieved pregnancy.  The authors concluded that carnitine may be the key component of the supplement cocktail for improving sperm quality. (Italian Archives of Urology and Andrology, September 2012)

LINK to ABSTRACT Prospective open-label study on the efficacy and tolerability of a combination of nutritional supplements in primary infertile patients with idiopathic astenoteratozoospermia.

 

Vitamin D helps leg ulcers heal
In this double-blind, placebo controlled trial, 26 patients Vitamins, Vitamin Dwith leg ulcers were given either placebo or 50,000 IU vitamin D weekly for two months.  Leg ulcer size, blood levels of vitamin D and pain was measured before and after the two month trial.  In the vitamin D group, leg ulcers were reduced in size by 28% while the placebo group had only a 9% reduction in ulcer size. The authors stated “there was a trend toward better healing in those with vitamin D reposition.” (Journal of Brazilian College of Surgeons, October 2012)

LINK to ABSTRACT Vitamin D and skin repair: a prospective, double-blind and placebo controlled study in the healing of leg ulcers.
LINK to FREE FULL TEXT

 

Complexity of methylation reactions gains insightmethyl donor, nutrients
This review emphasizes how methyl donor nutrients such as choline, folic acid and methionine interact and how consumption (via supplement or food) of one can have sparing effect s on another – such as choline’s  sparing effect on methionine, for example. (Current Opinion in Clinical Nutrition and Metabolic Care, January 2013)

LINK to ABSTRACT The nutritional burden of methylation reactions.
LINK to FLYER on NUTRIENT INTERACTIONS in METHYLATION

For more journal articles by disease or nutrient please click here

 

Topics: SpectraCell, serine, micronutrients, Coenzyme Q10, Oleic Acid, Cysteine, autoimmune diseases, zinc, Vitamin D, Carnitine, Magnesium, Choline, Vitamin C, Vitamin E, Vitamin A, Selenium, Vitamin B6, B Vitamins, Folic Acid, Antioxidants, lipoprotein particle profile, Omega 3 Fatty Acid, diagnostic tools, vitamin, wellness, pregnancy, Serum, Vitamin K, Vitamin B12, supplements, Multivitamins, Nutrition, diabetes, immune system, E-zinc, N-acetylcysteine, DNA, Calcium, Fertility, Lipoic Acid, deficiencies, health, Case Study, Omega 3s, Depression, Glutamine, Minerals, Neurotransmitters, Stress, Vitamin B1, micronutrient test, Vitamin B5, Vitamin B2, Nutritional Deficiency, Vitamin B3, cardiovascular disease, Hormones, Reproductive Health, Chromium, Manganese, Muscle recovery, Erectile Dysfunction, infertility, Niacin, Prostate, Energy, Methylation, Carbohydrate Metabolism

Can Nutrition Cure Depression?

Posted by SpectraCell Laboratories, Inc. on Fri, Dec 21, 2012 @ 11:09 AM

Presented by: Mary Ann Block, D.O.Depression, sad, nutrition

Topics of Discussion:

    • How Depression is Often a Symptom of Underlying Medical Problems
    • Nutrients Depleted by Antidepressants
    • Role of Zinc in the Development and Treatment of Mood Disorders
    • Case Study Review

 

Download our archived webinar presentation, "Can Nutrition Cure Depression?"

 

Also, check our webinar library for a complete list of previous webinars on a wide range of topics.

 

Topics: micronutrient testing, Antidepressants, autoimmune diseases, zinc, Vitamin D, Carnitine, Magnesium, Vitamin B6, B Vitamins, Antioxidants, Fatigue, Cholesterol, diagnostic tools, wellness, Vitamin B12, Multivitamins, Chronic Disease, E-zinc, deficiencies, chronic fatigue and nutrition, inositol, health, Case Study, website, Depression, Diet, Digestion, micronutrient test, Vitamin B2, Vitamin B3, Energy, Bipolar, webinar, Blood Pressure, Amino Acid, caffeine, Women's Health

SpectraCell's Nutritional Correlation Chart on Diabetes

Posted by Char Perez on Mon, Dec 03, 2012 @ 10:23 AM

Micronutrients such as niacin, magnesium, calcium, zinc, carnitine, inositol, alpha-lipoic acid, as well as vitamins E, B6 and D all play an important role in the prevention and treatment of diabetes.

Though diabetes is a serious disease - with the right treatment - living a longer, healthier life can be made easier.

THE ROLE OF MICRONUTRIENTS IN DIABETIC HEALTH

Vitamin E - Confers protection against diabetes by protecting pancreatic B-cells from nutrition reference chart for diabetesoxidativestress induced damage; May prevent progression of type I diabetes.

Vitamin D - Lowers risk of type I and 2 diabetes; Suppresses inflammation of pancreatic B-cells. Vitamin D receptor gene linked to diabetes.

Vitamin B3 - Preserves B-cell function in type I diabetics; Part of GTF (glucose tolerance factor) which facilitates insulin binding.

Vitamin B12 - Deficiency common in diabetics because metformin depletes B12.

Chromium - Helps insulin attach to cell's receptors increasing glucose uptake into cell; Deficiency can cause insulin resistance; Supplementation trials show dose-dependent benefits for type II diabetics.

Biotin - Stimulates glucose-induced insulin secretion in pancreatic B-cells; High dose biotin can improve glycemic control in diabetics.

Magnesium - Deficiency reduces insulin sensitivity; Low magnesium exacerbates foot ulcers in diabetics.

Zinc - Needed in the synthesis, storage and secretion of insulin; Protects pancreatic B-cells from damage; Affects the expression of genes linked to diabetes.

Lipoic Acid - Enhances glucose uptake in skeletal muscle tissue; Improves glucose tolerance in type 2 diabetics; very effective treatment for diabetic neuropathy.

Glutathione & Cysteine - Glutathione-containing enzymes protect B-cells which are particularly sensitive to oxidative stress; Type 2 diabetics have abnormal antioxidant status; Supplementation with the glutathione precursor cysteine restores antioxidant status.

Coenzyme Q10 - Protects kidney from diabetes related damage; Improves glycemic control in type 2 diabetics.

Glutamine - Stimulates a hormone called GLP-I (glucagon-like peptide I) that regulates insulin secretion after meals; Improves insulin signaling and sensitivity.

Carnitine - Reduces and even prevents pain from diabetic neuropathy; Improves insulin sensitivity by increasing glucose uptake and storage.

Inositol - Evidence suggests that inositol may be effective in treating diabetic neuropathy.

Vitamin C - Lowers glycolysated hemoglobin (HbA1c) and fasting and post-meal glucose levels and in type 2 diabetics.  

To assess a copy of the flyer which illustrates the interaction of micronutrients and their effect on patients' diabetes click here:  http://www.spectracell.com/media/disease-wheel-diabetes.pdf

Topics: SpectraCell, micronutrient testing, Coenzyme Q10, Cysteine, zinc, Vitamin D, Carnitine, Magnesium, Vitamin C, Vitamin E, B Vitamins, Vitamin B12, diabetes, immune system, Lipoic Acid, biotin, inositol, deficiency, Glutamine, Glutathione, micronutrient test, Wound Healing, Vitamin B3, reference chart, Chromium, Insulin

SpectraCell's Nutritional Correlation Chart on DEPRESSION

Posted by SpectraCell Laboratories, Inc. on Thu, Sep 20, 2012 @ 05:52 PM

Depression WheelBelow is a list of various nutrients that affect a person affected with depression.
  • Chromium - Elevates serotonin (feel-good neurotransmitter) levels in the brain; May be particularly effective on eating symptoms of depression such as carbohydrate craving and increased appetite, due to its effect on blood sugar regulation.
  • Magnesium - Deficiency damages NMDA (N-methyl-D-aspartate) receptors in the brain, which regulate mood; Well-documented anti-depressant effects.
  • Vitamin B12 - Depression may be a manifestation of B12 deficiency; Repletion of B12 to adequate levels can improve treatment response; B12 deficiency common in psychiatric disorders.
  • Vitamin B6 - Cofactor for serotonin and dopamine production (feel good chemicals); Studies indicate that low levels may predispose people to depression.
  • Vitamin B2 - Low B2 has been implicated in depression due to its role in methylation reactions in the brain.
  • Vitamin D - Clinical trials suggest increasing blood levels of vitamin D, which is actually a hormone precursor, may improve symptoms of depression.
  • Carnitine - Increases serotonin and noradrenaline which lift mood; In trials, carnitine alleviates depression with few, if any, side effects.
  • Inositol - Influences signaling pathways in the brain; Particularly effective in SSRI  (selective serotonin reuptake inhibitor) sensitive disorders.
  • Biotin - Part of the B-vitamin complex, biotin deficiency has induced depression in animal and human studies.
  • Antioxidants - Oxidative stress in the brain alters neurotransmitter function; Antioxidants protect our brain, which is very sensitive to oxidation; Several antioxidants – Vitamins A, C and E, Lipoic Acid, CoQ10, Glutathione and Cysteine – play a key role in prevention and treatment of depression.
  • Serine - Regulates brain chemistry; Involved in NMDA receptor function; Acts as a neurotransmitter; Low levels correlate with severity of depression.
  • Zinc - Improves efficacy of antidepressant drugs; Particularly useful for treatment resistant patients; Regulates neurotransmitters.
  • Selenium - Integral part of regulatory proteins (selenoproteins) in the brain; Supplementation trials are promising; May alleviate postpartum depression.

To learn more, visit our Clinical Education Center's handouts section!

 

 

Topics: serine, zinc, Vitamin D, Carnitine, Magnesium, Selenium, Vitamin B6, Antioxidants, Vitamin B12, biotin, inositol, Depression, Vitamin B2, Chromium

Why Do We Get PMS?

Posted by SpectraCell Laboratories, Inc. on Tue, Jul 31, 2012 @ 11:20 AM

The Fatigue SolutionExcerpt from Eva Cwynar, M.D.'s new book, "The Fatigue Solution"

We've come a long way since the time when doctors used to debate the reality of PMS, but the short answer is that there are many reasons why PMS occurs. There are several different theories:

  • Decline in progesterone levels. PMS symptoms occur during the luteal phase of a woman's cycle, which is when progesterone begins to rise (right after ovulation) and then starts to plummet about 7 days later. When you are about to get your period, your progesterone levels rapidly drop. That's what causes problems. Hormone levels normally fluctuate. If progesterone levels were measured on a scale of 1 to 10, for example, they could drop from a level of 10 to a 9.9 to a 9.8 to a 9.7 and your body would be able to adjust to the changing levels with almost no difficulty. When you're about to get your period, however, levels drop dramatically from a 10 to a 5 and perhaps even to a 1. It's that rapid change that stimulates your symptoms. And some women drop faster and lower than others, which is why their symptoms may be worse than other women's.
  • Decrease in neurotransmitters serotonin and GABA activity. Serotonin is responsible for our positive emotional well-being, while GABA helps keep us calm. Reduced levels of estrogen during the luteal phase may ben linked to a drop in serotonin. Lower serotonin levels are associated with irritability, anger, and carbohydrate cravings, all of which are symptoms of PMS. It also appears that GABA receptors are less sensitive than normal, which would explain the increased sense of anxiety.
  • Changes in levels of norepinephrine and epinephrine. These neurotransmitters are involved in the body's stress response. Estrogen may affect the levels of these neurotransmitters, which can influence blood pressure and heart rate as well as mood.

Other possible causes include:

  • Hypoglycemia (low blood sugar)
  • Mercury toxicity
  • Hypothyroidism
  • Candida overgrowth (a fungus)
  • Food allergies/sensitivities
  • Vitamin B6, Calcium or Magnesium deficiencies
  • Inadequate protein intake - liver enzymes that convert female hormones depend on protein
  • Poor liver function - the liver metabolizes one form of estrogen into other forms of estrogen
  • Poor adrenal gland function

No one knows for sure what causes PMS. Some people attribute particular symptoms to increased levels of estrogen and/or progesterone; other people say the same symptom is due to decreased levels of these hormones. Studies routinely produce conflicting results. I believe that the key to eliminating or greatly reducing PMS symptoms lies in the balance between these two hormones during the menstrual cycle.

Learn more about this topic below:

Also, to learn more about Dr. Eva Cwynar, visit her website: www.dreva.com

 

Topics: Magnesium, Vitamin B6, Fatigue, Calcium, PMS, Hormones, Dr. Eva Cwynar

NEW! SpectraCell's Asthma Quick Reference Chart

Posted by SpectraCell Laboratories, Inc. on Thu, Jul 26, 2012 @ 10:12 AM

Asthma WheelDuring last week's webinar, "Nutritional Considerations of Allergies & Asthma", we created and offered a copy of our new "Asthma Quick Reference Nutrient Chart".  This visual tool is an excellent resource to emphasize to your patients the many inter-related roles that nutrition plays in disease prevention and management.

View and/or download our flyer on Asthma HERE.

You can also view the rest of our library of quick reference nutrient charts HERE. Each chart is available as an individual handout and includes references posted on the reverse side. Our clients can order supplies by calling us at 800-227-5227 or visiting our Physician Access Center.


Topics: Coenzyme Q10, zinc, folate, Vitamin D, Carnitine, Magnesium, Choline, Vitamin C, Vitamin E, Vitamin A, Selenium, Vitamin B6

Recorded Webinar: Nutritional Considerations of Allergies and Asthma

Posted by SpectraCell Laboratories, Inc. on Wed, Jul 25, 2012 @ 10:55 AM

Allergies & AsthmaPresented by: Ron Grabowski, R.D., D.C.

Topics of Discussion:
  • How does the gastrointestinal tract affect allergies?
  • What nutrients act as antihistamines?
  • How do certain medications for asthma affect an individual's nutritional status?
  • Why is magnesium so important to the COPD patient?
Click HERE to listen to our recorded webinar as well as download the corresponding presentation slides.

Topics: Magnesium, Nutrition, Dr. Ron Grabowski, Gastrointestinal Tract, Allergies, Antihistamines, Asthma

Nutritional Considerations of Pain

Posted by SpectraCell Laboratories, Inc. on Mon, Jul 23, 2012 @ 09:20 AM

PainBelow is a list of various nutrients that affect a person affected with body pain.

  • Cysteine - reduces pain caused by systemic inflammation due to its potent antioxidant properties.
  • Inositol - in animal studies, treatment with inositol induces antinociception (pain reduction).
  • Oleic Acid - this fatty acid is a precursor of oleamide, an analgesic that affects neurotransmitters such as dopamine, serotonin, acetylcholine and GABA (gamma amino butyric acid), all of which play a role in pain signaling.
  • Carnitine - deficiency of this amino acid may manifest as muscle weakness, pain (myalgia) or neuropathy. Supplementation reduces several types of chronic pain.
  • Magnesium - lowers pain by blocking NMDA receptors in spinal cord; effective in reducing post-operative pain.
  • Minerals:
    • Manganese - a cofactor for the potent antioxidant superoxide dismutase, which fights free radicals, a known source of pain.
    • Copper - supplementation can relieve arthritic pain.
    • Selenium - treatment with this mineral improves muscle pain in deficient patients.
    • Zinc & Calcium - research suggests both play a role in the transmission of pain signals through nerves.
  • Choline - activates specific receptors in brain and spine that lower acute pain.
  • Vitamin B1, B2, B6, B12 - these produce a dose dependent decrease in various kinds of pain (heat, pressure, chemical); increases sensitivity to pain meds; their effect is likely mediated through serotonergic neurotransmitters.
  • Vitamin D - deficiency often presents clinically as muscle or bone pain.
  • Lipoic Acid - very effective treatment for neuropathic pain.
  • Antioxidants - clinical trials show antioxidant therapy is an effective treatment for chronic pain
    • Vitamin E - reduces neuropathic pain
    • Vitamin C - can lower morphine consumption after surgery
    • Coenzyme Q10 - relieves statin-induced myopathy.

Download our 1-page flyer which illustrates the information above, HERE!

Topics: Coenzyme Q10, Oleic Acid, Cysteine, zinc, Vitamin D, Carnitine, Magnesium, Choline, Vitamin C, Vitamin E, Selenium, Vitamin B6, Copper, Antioxidants, Pain, Vitamin B12, Calcium, Lipoic Acid, inositol, Vitamin B1, Vitamin B2, Manganese

Nutritional Considerations of Insomnia

Posted by SpectraCell Laboratories, Inc. on Tue, Jul 17, 2012 @ 05:10 PM

InsomniaBelow is a list of various nutrients that affect a person with Insomnia.
  • Vitamin B3 (niacin) - increases REM sleep; improves both quality and quantity of sleep by converting trytophan to serotonin.
  • Folate & Vitamin B6 - both are cofactors for several neurotransmitters in the brain such as serotonin and dopamine, many of which regulate sleep patterns.
  • Vitamin B12 - normalizes circadian rythms (sleep-wake cycles); therapeutic benefits of B12 supplementation, both oral and intravenous, seen in studies.
  • Magnesium - improving magnesium status is associated with better quality sleep; mimics the action of melatonin; also alleviates insomnia due to restless leg syndrome.
  • Zinc & Copper - both interact with NMDA (N-methyl-D-aspartate) receptors in the brain that regulate sleep; a higher Zn/Cu ratio is linked to longer sleep duration.
  • Oleic Acid - this fatty acid is a precursor of oleamide, which regulates our drive for sleep and tends to accumulate in the spinal fluid of sleep-deprived animals. Oleic acid also facilitates the absorption of vitamin A.
  • Vitamin A - studies suggest vitamin A deficiency alters brain waves in non-REM sleep causing sleep to be less restorative.
  • Vitamin B1 (thiamin) - in clinical trials, supplementation of healthy individuals that had marginal B1 deficiency improved their sleep.

Download our 1-page flyer which illustrates the information above, HERE!

 

Topics: Oleic Acid, zinc, folate, Magnesium, Vitamin A, Vitamin B6, Copper, Vitamin B12, Vitamin B1, Vitamin B3