SpectraCell Blog

SpectraCell's Nutritional Correlation Chart on Autism

Posted by SpectraCell Laboratories, Inc. on Wed, Feb 06, 2013 @ 01:54 PM

Autism Nutritional WheelVitamin D - High dose vitamin D therapy reversed autistic behaviors in severely deficient children; Maternal vitamin D deficiency may predispose children to autism.3,4,5

Vitamin A - One cause of autism may be a defect in a retinoid receptor protein (G-alpha protein) which is critical for language processing, attention and sensory perception; Evidence suggests natural vitamin A fixes this protein defect in autistics.1,2

Folate - Oral folate therapy can resolve symptoms of autism in some cases, particularly in autistics with genes that impair folate dependent enzymes.31,32,33

Glutamine - Blood levels of this amino acid which acts as a neurotransmitter are particularly low in autistics. Glutamine also helps prevent leaky gut syndrome, which can exacerbate autistic symptoms.28,29,30

Vitamin C - Improved symptom severity and sensory motor scores in autistic patients possibly due to interaction with dopamine synthesis; Vitamin C also has a strong sparing effect on glutathione.26,27

Glutathione & Cysteine -  Commonly deficient in autistic patients, lack of these antioxidants impair detoxification and methylation processes; Low levels linked to neurological symptoms in autism which is often considered an oxidative stress disorder.21,22,23,24,25

Vitamin B1 - Deficiency linked to delayed language development; Supplementation may benefit autistic patients.19,20

Vitamin B12 - Low B12 impairs methylation (detoxification) which causes the neurological damage responsible for many autistic symptoms; Deficiency of B12 can cause optic neuropathy and vision loss in autistics; B12 raises cysteine and glutathione levels.16,17,18

Vitamin B6 - Cofactor the neurotransmitters serotonin and dopamine; Conversion of B6 to its active form is compromised in many autistics; Supplementation trials with B6 resulted in better eye contact, speech and fewer self-stimulatory behavior in autistics; Some consider B6 in combination with magnesium to be a breakthrough treatment for autism.14,15

Magnesium - Cofactor for the neurotransmitters that affect social reactions and emotion; Autistics have low levels; Improves effectiveness of B6 therapy.11,12,13

Zinc - Eliminates toxic mercury from brain tissue; Zinc/ copper ratio is particularly low in autistic kids; Low zinc impairs  the protein (called metallothionein) that removes heavy metals from the body.8,9,10

Carnitine - Transports fatty acids into cells; Low carnitine (common in autism) impairs the ability to use fatty acids for learning and social development.6,7

 For a copy of Spectracell's Nutrition Correlation chart on Autism click here

Topics: micronutrients, micronutrient testing, Cysteine, Antidepressants, zinc, folate, Vitamin D, Carnitine, Magnesium, Vitamin C, Vitamin A, Vitamin B6, B Vitamins, Antioxidants, diagnostic tools, supplements, autism, Vitamins, DNA, deficiencies, health, deficiency, Depression, Glutamine, Neurology, Glutathione, Diet, Minerals, Digestion, Brain, Nervous System, Neurotransmitters, Aggression, Stress, Vitamin B1, degenerative illness, micronutrient test

Vitamins, minerals and antioxidants can help!

Posted by SpectraCell Laboratories, Inc. on Thu, Jan 10, 2013 @ 01:20 PM

Is carnitine the answer for male infertility?male, infertility
A group of men (n=96) who had been diagnosed as infertile for at least 18 months were given the following nutritional formulation daily for four months: L-carnitine, acetyl-L-carnitine, fructose, citric acid, selenium, coenzyme Q10, zinc, vitamin C, vitamin B12 and folic acid (see abstract for exact dosages).  At the end of the study, sperm motility improved and 16 of the patients had achieved pregnancy.  The authors concluded that carnitine may be the key component of the supplement cocktail for improving sperm quality. (Italian Archives of Urology and Andrology, September 2012)

LINK to ABSTRACT Prospective open-label study on the efficacy and tolerability of a combination of nutritional supplements in primary infertile patients with idiopathic astenoteratozoospermia.

 

Vitamin D helps leg ulcers heal
In this double-blind, placebo controlled trial, 26 patients Vitamins, Vitamin Dwith leg ulcers were given either placebo or 50,000 IU vitamin D weekly for two months.  Leg ulcer size, blood levels of vitamin D and pain was measured before and after the two month trial.  In the vitamin D group, leg ulcers were reduced in size by 28% while the placebo group had only a 9% reduction in ulcer size. The authors stated “there was a trend toward better healing in those with vitamin D reposition.” (Journal of Brazilian College of Surgeons, October 2012)

LINK to ABSTRACT Vitamin D and skin repair: a prospective, double-blind and placebo controlled study in the healing of leg ulcers.
LINK to FREE FULL TEXT

 

Complexity of methylation reactions gains insightmethyl donor, nutrients
This review emphasizes how methyl donor nutrients such as choline, folic acid and methionine interact and how consumption (via supplement or food) of one can have sparing effect s on another – such as choline’s  sparing effect on methionine, for example. (Current Opinion in Clinical Nutrition and Metabolic Care, January 2013)

LINK to ABSTRACT The nutritional burden of methylation reactions.
LINK to FLYER on NUTRIENT INTERACTIONS in METHYLATION

For more journal articles by disease or nutrient please click here

 

Topics: SpectraCell, serine, micronutrients, Coenzyme Q10, Oleic Acid, Cysteine, autoimmune diseases, zinc, Vitamin D, Carnitine, Magnesium, Choline, Vitamin C, Vitamin E, Vitamin A, Selenium, Vitamin B6, B Vitamins, Folic Acid, Antioxidants, lipoprotein particle profile, Omega 3 Fatty Acid, diagnostic tools, vitamin, wellness, pregnancy, Serum, Vitamin K, Vitamin B12, supplements, Multivitamins, Nutrition, diabetes, immune system, E-zinc, N-acetylcysteine, DNA, Calcium, Fertility, Lipoic Acid, deficiencies, health, Case Study, Omega 3s, Depression, Glutamine, Minerals, Neurotransmitters, Stress, Vitamin B1, micronutrient test, Vitamin B5, Vitamin B2, Nutritional Deficiency, Vitamin B3, cardiovascular disease, Hormones, Reproductive Health, Chromium, Manganese, Muscle recovery, Erectile Dysfunction, infertility, Niacin, Prostate, Energy, Methylation, Carbohydrate Metabolism

Nutritional Considerations of ADHD & Autism

Posted by SpectraCell Laboratories, Inc. on Mon, Jan 23, 2012 @ 01:58 PM

ADHD & AutismADHD and AUTISM ON THE RISE
Recent years has seen an unprecedented rise in autism and attention deficit hyperactivity disorder (ADHD).

Although researchers speculate on the reason for this rise, many factors likely contribute, including more accurate diagnosis. However, overwhelming evidence suggests that nutritional deficiencies may be a contributing factor.

OMEGA-3 FATTY ACIDS ARE KEY
Our brain and nerves are composed mostly of fat. The most important of these are called omega-3 fatty acids and are found primarily in fish or fish oil supplements. Also called EPA and DHA, they are absolutely necessary for human health, and their concentration in the brain makes them key players in neurological disorders such as autism and ADHD. Brain and nerve growth throughout childhood is extraordinarily rapid, and the need for omega-3 fatty acids remains critical all the way through adolescence and into adulthood. Overwhelming evidence implicates deficiencies in omega-3 fatty acids for the rise in autism and ADHD. Research shows that children with low scores on behavioral assessment tests consistently have lower omega-3 fatty acids levels, and when supplemented with fish oils, the symptoms of ADHD in these children such as hyperactivity, impulsiveness, and inability to pay attention - dramatically improve.

Omega 3 & 6WHY MEASURE THE OMEGA-6 TO OMEGA-3 RATIO?
We are familiar with the expression that a child’s brain is like a sponge, ready to absorb information at an astounding rate. A truly appropriate analogy, it stems from the fact that our brains can actually create nerve pathways in response to new experiences and learning environments. Called “neuronal plasticity,” this phenomena is crucial for long-term memory and learning. Proper levels of the omega-3 fatty acid, DHA (docosahexaenoic acid), is important for membrane fluidity. The ratio of omega-6 fatty acids, which differ in structure and function, to omega-3 fatty acids affect neuronal plasticity as well. Scientists now agree that the ratio of omega-6 fats to omega-3 fats is as important as the actual levels, especially in autism and ADHD. A lower ratio is better and when this ratio is improved, symptoms of autism and ADHD can improve as well.

ZINC – THE MOOD MINERAL
Zinc deficiency is often implicated in ADHD because it is an important co-factor to several neurotransmitters, which directly affect mood and learning ability. Specifically, zinc affects the production of dopamine, a feel-good chemical in our brains that is needed for learning and certain emotions like motivation and pleasure. In fact, studies show that zinc levels correlate with anxiety and behavioral problems, as well as have a significant effect on information processing in boys with ADHD. Since zinc levels are much lower in autistic and ADHD individuals, children with ADHD show positive behavioral and cognitive results after zinc supplementation.In addition, zinc is essential for proper elimination of the toxic metal mercury from our brain tissue, which has also been linked to autism and ADHD.

Vitamins & AutismVITAMINS AND AUTISM
Low levels of vitamin D have been linked with autism and in some cases of severe deficiency, high-dose vitamin D therapy actually reversed some of the autistic behaviors. Some research even suggests that the nutritional status of the mother during gestation can affect behavior in children. One study confirmed that low folate status in pregnancy was associated with hyperactivity in children. Other studies show that persons who carried a common gene that predisposes them to folate and vitamin B12 deficiency (called the MTHFR gene) were more likely to suffer from ADHD. Supplementation with thiamine (vitamin B1) has shown clinical benefit to some autistic children. Specifically, a deficiency in vitamin B1 has been associated with delayed language development in childhood.When deficient, biotin (vitamin B7) can potentially cause neurological problems associated with autism since the brain is quite vulnerable to biotin deficiency.

MAGNESIUM AND VITAMIN B6 – A WINNING COMBINATION
Like most nutrients, magnesium and vitamin B6 work together in improving clinical symptoms of autism and ADHD.

When a group of autistic children were supplemented with magnesium and vitamin B6, 70% of the children showed improvement in social interaction and communication. Interestingly, when the supplements were stopped, the clinical symptoms reappeared. In another study, physical aggression and inattention improved after supplementation with magnesium and vitamin B6 for a few months.

NeurotransmittersTHE ROLE OF NEUROTRANSMITTERS
Neurotransmitters are tiny chemicals that transmit information from the outside world to various parts of our brains and from our brains to the rest of our bodies. Although neurotransmitters, such as choline, glutamine, asparagine and inositol may not be recognized as household names, they profoundly affect emotions, thinking and social behavior. For example, levels of glutamine and asparagine are lower in autistic children and some adults with ADHD.

AN AMINO ACID THAT IMPROVES CARNITINE – BEHAVIOR
Carnitine is an amino acid whose primary function is to transport fatty acids, including the ever-so-important omega-3 fatty acids into cells so they can be used for energy. In autistic individuals, carnitine levels are significantly reduced, which then affects the patient’s ability to use the fatty acids that are so critical to their learning and social development.
A recent study demonstrated that carnitine can reduce hyperactivity and improve social behavior in boys diagnosed with ADHD, and may actually represent a safe alternative to the use of stimulant drugs for the treatment of ADHD in children.

ADHD AND AUTISM – AN OXIDATIVE STRESS DISORDER?
Oxidative stress is a term used to describe damage to our cells that occurs on a daily basis throughout our bodies. Fortunately, our bodies have built-in defenses against the onslaught of internal and external toxins causing oxidative stress in our tissues. Interestingly, several studies show an increase in oxidative stress in both autism and ADHD, resulting in an impaired ability to eliminate toxins. Specifically, adults with ADHD have extremely low levels of some of the most powerful antioxidants in the body. One study linked damage in fatty tissue surrounding our cells to symptoms of autism and ADHD. Minerals such as selenium and copper, antioxidants such as cysteine and vitamin E and several other nutrients ensure the body’s powerful defense systems work optimally.

ADHD & AutismA MULTI-FACETED APPROACH
Since so many nutrients are needed to keep our amazingly complex brain and nervous system functioning properly, a comprehensive assessment of your nutritional status is key. In disorders like autism and ADHD, the potential improvement of symptoms when even a single deficiency is corrected can often be quite dramatic.

For more information, contact us at [email protected] or call 800-227-5227.

Topics: zinc, Carnitine, Magnesium, Vitamin B6, Omega 3 Fatty Acid, vitamin, autism, Omega 3s, Neurotransmitters, ADHD, Nutritional Deficiency, Oxidative Stress, Omega 6