SpectraCell Blog

Estrogen Metabolism and its Clinical Applications

Posted by SpectraCell Laboratories, Inc. on Fri, Jun 12, 2015 @ 12:50 PM


SpectraCell's Educational webinar series hosted every month addresses how various diagnostic tools can aide in improving patient outcomes. To view our complete webinar library, please be sure to visit by clicking here.

One of our most recent webinar presentations is highlighted below.  The presentation gives the viewer a detailed look into understanding methylation processes and key components that may or may not affect estrogen metabolism presented by Dr. Karan Y. Baucom an expert in the field.

Estrogen Metabolism and its Clinical Applications

Presented by Karan Y. Baucom, MD

  • Overview of the methylation process and its effects on clinical conditions
  • Understand key components of the biochemical pathways affecting methylation and estrogen metabolism
  • The role of nutrition in the methylation process and estrogen metabolism
  • Case Study Review

Click on the image below to view SpectraCell's webinar on "Estrogen Metabolism and its Clinical Applications."



Estrogen_Metabolism__its_Clinical_Applications_Dr._Karan_Baucom_Page_01

 

 

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SpectraCell is at the forefront of providing a variety of resources to further expand our followers' knowledge in the area of integrative health. To learn more about the tests SpectraCell offers, please visit www.spectracell.com and to register for future webinars please check www.spectracell.com/webinars.



 

Topics: SpectraCell, Hormones, Methylation, Estrogen, Metabolism

Study suggests testosterone therapy in men not harmful to prostate...

Posted by SpectraCell Laboratories, Inc. on Fri, Mar 06, 2015 @ 11:04 AM

 

Recent finding suggests testosterone therapy in men not harmful to prostatetestosterone


In a recently published study, 1023 hypogonadal men who received testosterone therapy were monitored for an average of 5 years for prostate cancer. The authors concluded that “testosterone therapy in hypogonadal men does not increase the risk of prostate cancer” although the authors did explicitly note that there was not control group in this study of men not taking testosterone.

Similar conclusions were reported in a different review of a testosterone replacement therapy in men, although the effect of testosterone on cardiovascular disease and events was much less clear. Whether or not to treat men with testosterone remains equivocal, as highlighted in the clinical decisions case study listed below.
(Journal of Urology, January 2015)
(Therapeutic Advances in Drug Safety, October 2014)
(New England Journal of Medicine, November 2014)

LINK to ABSTRACT Incidence of prostate cancer in hypogonadal men receiving testosterone therapy: observations from 5-year median followup of 3 registries.
LINK to ABSTRACT
Adverse effects of testosterone replacement therapy: an update on the evidence and controversy. LINK to FREE FULL TEXT
LINK to CASE STUDY 
Clinical decisions. Testosterone-replacement therapy.

For more information or to get tested, please visit www.spectracell.com

 

Topics: SpectraCell, micronutrient, Hormones, Testosterone

SPECTRACELL ANNOUNCES NEW PRODUCT ENHANCEMENTS

Posted by SpectraCell Laboratories, Inc. on Mon, Feb 16, 2015 @ 03:11 PM

SpectraCell is expanding their hormone and thyroid test menu. hormones

Like nutrients, hormones influence all aspects of health and disease - mood, sleep, metabolism, immunity, heart health and appearance.  An imbalance of one hormone can initiate a cascade of events that alters other hormones, so a comprehensive look at hormone status is key. Thyroid hormones directly regulate every cell in our body as most basic functions like metabolism, emotions and thinking. The below components have been added to our already established hormone and thyroid test.

Estrone sulfate (E1) – Included in our male and female hormone profiles

This estrogen has very strong tissue proliferative effects and may be linked to estrogen dominant conditions like fibrocystic breasts, endometriosis and uterine fibroids. It will create either dangerous or beneficial metabolites, depending on a person's nutritional status.

Estriol, unconjugated (E3) – Included in our female hormone profile

Estriol is a weak estrogen that is very high during pregnancy, but also plays an important role in non-pregnant women by opposing the growth of cancer cells promoted by the stronger estrogens E1 and E2.  Estriol is also known to alleviate menopausal symptoms such as hot flashes or urinary incontinence.

Reverse Triiodothyronine (Reverse T3) – Must be ordered individually

As the name implies, Reverse T3 opposes the biological action of T3.  It slows metabolism and renders T3 in the body biologically inactive. The rate of rT3 production relative to T3 will increase in times of stress (high cortisol) and in the presence of nutrient deficiencies, inflammation or certain medications.

To learn more about how to get tested, please visit our GET TESTED page HERE.

Topics: SpectraCell, Thyroid, micronutrient, Hormones

The Endocrine Disorder in America NO ONE is Talking About

Posted by SpectraCell Laboratories, Inc. on Thu, Jan 22, 2015 @ 09:16 AM

thyroid resized 600There are currently about 25 million Americans diagnosed with some sort of thyroid disorder.  Thyroid disorders tend to be more prominent in women and the probability of a thyroid disorder occurring is four times more likely in women than in men. 

 

What exactly is the thyroid?

  • A butterfly shaped gland in the neck
  • Makes T3 , T4 and calcitonin (calcium regulating hormone)

Symptoms of a Thyroid disorder

  • Weight gain, even though you are not eating more food.
  • Increased sensitivity to cold.
  • Constipation.
  • Muscle weakness.
  • Joint or muscle pain.
  • Depression.
  • Fatigue (feeling very tired)
  • Pale dry skin.

Watch SpectraCell's webinar on
Integrative Diagnostics for Managing the Thyroid HERE                                                  

Topics: SpectraCell, Thyroid, weakness, Hormones, Weight Gain, endocrine disorder

The Role of Nutrition in Hormonal Health

Posted by SpectraCell Laboratories, Inc. on Fri, Jan 09, 2015 @ 10:57 AM

Hormone Balance Logo resized 600Micronutrients profoundly affect hormonal health.  It is difficult to achieve hormonal balance if micronutrient status is inadequate, and like nutrients, hormones affect cellular metabolism, energy production, detoxification efficiency and mental health so balance is Key. 

Like nutrients, hormones influence all aspects of health and disease - mood, sleep, metabolism, immunity, heart health and appearance.  An imbalance of one hormone can initiate a cascade of events that alters other hormones.  
  • Fatigue & Energy Levels
  • Cardiovascular health (Blood pressure, clotting, lipids)
  • Neurology (migraines, sleep, pain)
  • Mental Health (depression, anxiety, cognitive function)
  • Immunity (infections, autoimmune disease)
  • Metabolism (blood sugar regulation, tissue repair)
  • Bone density (Osteoporosis)
  • Physical appearance (skin, muscles, hair)
SpectraCell Laboratories offers comprehensive male and female hormone panels that reveal the overall state of hormonal balance in a patient.

A comprehensive look at your hormone status is key.

GET TESTED!

Topics: SpectraCell, Vitamins, micronutrient, Hypothyroidism, Hormones, Menopause, infertility, Women's Health

SpectraCell Launches NEW Products!

Posted by SpectraCell Laboratories, Inc. on Thu, Jul 31, 2014 @ 10:13 AM

spectracell, hormones, micronutrient, genetics, cardioAt SpectraCell Laboratories we are always looking for ways to look at the overall health of a patient and in turn providing you with the tools necessary to provide a customized treatment plan where the focus is "Balance is Key" to healthy living.

SpectraCell Laboratories, the leader in functional nutritional testing is proud to announce the launch of our new comprehensive hormone testing and CardioMetabolic with a Pre-diabetes panel to its menu. Below you will find a brief description of each of the tests we are now offering to our clients.     

CARDIOMETABOLIC TESTING 

SpectraCell Laboratories, primarily known for its functional nutritional testing, now offers a complete Cardiometabolic Panel to measure risk of heart disease and diabetes.   The new panel, which includes SpectraCell’s advanced Lipoprotein Particle Profile™,   reports several clinically relevant biomarkers in three areas:  (1) Glycemic control  (2) Lipid Metabolism and (3) Vascular Inflammation.  Each patient is given a pre-diabetic risk score ranging from 1 to 8 depending on their results. As a clinician, you can monitor both their specific biomarkers as well as their composite risk and treat accordingly.  Assessing cardiometabolic function is the first step in treating it. 

HORMONE TESTING

Complete male and female panels are now available.  Both end-point steroid hormones as well as precursor hormones are included so the precise place of imbalance in the complicated hormonal cascade can be pinpointed.  Several peptide hormones are also included as well as a complete thyroid panel, including thyroid antibody testing.  Like nutrients, an imbalance of one hormone can initiate a cascade of events that alters other hormones, so a comprehensive look at hormone status is essential.

For more information on our new tests or to receive a product guide booklet, complete form

Topics: SpectraCell, diabetes, Thyroid, micronutrient, Hormone, Cardio, Metabolic

Zinc, the MINERAL you should know about

Posted by SpectraCell Laboratories, Inc. on Wed, May 07, 2014 @ 10:02 AM

The primary role of zinc is to activate almost 200zinc enzymes with vital roles in cell regulation, immune function, acid/base balance, DNA, RNA, and protein synthesis, lipid metabolism, eicosanoid production, and digestion.

Zinc also is a component of insulin (energy metabolism), thymic hormones (immune function) and gustin (taste acuity).

Deficiency  Symptoms:

Symptoms of zinc deficiency include fatigue, dermatitis, acne, loss of taste, poor wound healing, anorexia, decreased immunity, delayed growth, hypogonadism and delayed sexual maturation, diarrhea, skeletal abnormalities, alopecia, behavioral disturbances, white spots on fingernails, infertility and night blindness.

Those at risk for zinc deficiency include alcoholics, malnourished, malabsorption (Crohn’s Disease, celiac disease), long-term  parenteral nutrition, chronic renal disease, anorexics, dieters, pregnant women, elderly, and sickle-cell disease.

Repletion  Information:

Dietary sources rich in Zinc (per serving) are:

  • Red Meats                              
  • Wheat Germ
  • Seeds                                   
  • Nuts
  • Soybean Products                
  • Legumes
  • Potatoes                                  
  • Zinc-Fortified Cereal Products

Compounds found in meats enhance absorption of zinc from plant sources.

Download SpectraCell's Nutrient Correlation Wheel on Hypothyroidism, fatigue and weight management all showing the correlation with these have with zinc deficiency.

GET TESTED!

Topics: SpectraCell, micronutrients, zinc, micronutrient test, vitamin deficiencies

A Look at Carnitine

Posted by SpectraCell Laboratories, Inc. on Mon, Apr 14, 2014 @ 03:37 PM

anatomy of nutrition blank resized 600

L-carnitine is an amino acid derivative of the essential amino acids L-lysine and methonine. The conversion to carnitine requires niacin (B3), vitamins B6 and C, and iron.  It is found in nearly all cells of the body but chiefly in the liver and kidney.  Carnitine is essential for the transportation of long-chain fatty acids across the inner mitochondrial membranes in the mitochondria, where they are metabolized by beta-oxidation to produce biological energy in the form of adenosine triphosphate (ATP).

L- carnitine also is required to remove short- and medium-chain fatty acids from the mitochondria.  This removal optimized energy production by maintaining coenzyme A at optimal levels for normal metabolism and energy production.

Deficiency Symptoms:

Deficiencies of carnitine may result from 1) deficiencies of essential amino acids lysine and methionine, 2) deficiencies of cofactors (B3, C, B6 and iron), 3) defective gastrointestinal function, 4) increased requirement because of high-fat diet, metabolic stress or disease.  The consequences of carnitine deficiency are impaired lipid metabolism and lipid accumulation in skeletal muscles, heart and liver. Patients usually exhibit muscle weakness and fatigue.

Normal heart function depends on adequate concentrations of carnitine.  While the normal heart stores more carnitine than required, if the heart does not have a good oxygen supply, carnitine levels quickly decrease.  This lack of oxygen leads to decreased energy production and increased risk for angina and heart disease.  Carnitine benefits blood lipids by lowering triglycerides and total cholesterol, while increasing HDL.  L-acetylcarnitine (LAC) may be useful in the treatment of Alzheimer's disease, senile depression and age-related memory loss.

Download the nutrient correlation chart on Fibromyalgia, Pain and Testosterone all include a deficiency in carnitine.

GET TEST TODAY!

Topics: SpectraCell, Carnitine, Vitamins, deficiency, micronutrient test, micronutrient, vitamin deficiencies, weakness

Magnesium, Vital for Proper Cell Function

Posted by SpectraCell Laboratories, Inc. on Thu, Mar 27, 2014 @ 02:32 PM

Magnesium is predominantly found intracellularly, wheremagnesium it is vital for proper cell functions. Magnesium is the second most prevalent intracellular cation (after potassium).  Magnesium functions are numerous and essential, including enzyme activation (over 300 types), neuromuscular activity, membrane transport and interactions, energy metabolism (carbohydrates, fats, proteins), and roles in calcium and phosphorus metabolism. 

Deficiency  Symptoms

Deficiency symptoms are both acute (Trouseau and Chvostek signs, muscle spasms, tetany, cardia arrythmias, ataxia, vertigo, convulsions, organic brain syndrome) and chronic (thrombophlebitis, hemolytic anemia, bone loss, depressed immune function, poor wound healing, hyper irritability, burxism, hyperlipidemia, fatigue, hypertension). Those at risk for Magnesium deficiency include:  malabsorption, malnourished, alcoholics, diabetics, diuretic therapy, children, elderly, pregnant and lactating women, post menopausal women with osteoperosis, athletes, digitalis therapy, long-term therapy with antibiotics, chemotherapeutic and immunosuppressive medications.  In addition, the following diseases are associated with Magnesium deficiency:  cardiovascular disease, cirrhosis, renal disease, parathyroid diseases, thyroid conditions.

Repletion  Information
Dietary sources richest in Magnesium (per serving) are:
  • Nutritional Supplements  
  • Seeds (especially  pumpkin)
  • Nuts 
  • Soybeans
  • Whole Grains     
  • Potatoes
  • Legumes
  • Fresh Vegetables
Watch or download Dr. Grabowski's presentation on "Connecting the Nutrients" here

Get Tested Today!

 

Topics: SpectraCell, micronutrient testing, Multivitamins, Vitamins, Minerals, micronutrient, Nutrient

The Need for Glutathione

Posted by SpectraCell Laboratories, Inc. on Thu, Mar 20, 2014 @ 11:28 AM

glutathioneGlutathione is implicated in many cellular function including antioxidant protection and detoxification. It is also essential for the maintenance of cell membrane integrity in red blood cells. Intracellular glutathione concentrations are principally derived by intracellular synthesis, as few cells directly uptake glutathione from the surrounding extracellular fluid.  The high concentration of glutathione in virtually all cells clearly indicates its importance in metabolic and oxidative detoxification processes.  Glutathione may be considered the preeminent antioxidant. 

Deficiency Symptoms

A wide range of human conditions such as aging, cancer, atherosclerosis, arthritis, viral infections, AIDS, cardiovascular, neurodegenerative diseases and pulmonary diseases may be produced or made worse by "free radicals." Their treatment or prevention often includes antioxidants such as vitamin C, vitamin E, carotenoids and selenium.  Glutathione is an essential component of the antioxidant defense system: producing a "sparing effect" for both tocopherol and ascorbate by reducing the oxidized forms, and by eliminating hydrogen peroxide by reacting with glutathione peroxidase.  Cellular glutathione functions to decrease the formation of oxidized LDL, implicated in the development of atherosclerosis. T-lymphocytes become deficient in glutathione in the progression of AIDS which impairs immune function.  Glutathione is also required for the synthesis of some prostaglandins from n-3 and n-6 polyunstaturated fatty acids which are important in the inflammatory response.  Patients with adult respiratory distress syndrome are favorably affected by treatments that increase cellular glutathione.

Download our Nutrient Function and Deficiency symptoms handout here.

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Topics: SpectraCell, micronutrient testing, Glutathione, Stress, Aging, Muscle recovery, Energy