SpectraCell Blog

Exercise: A Fountain Of Youth?

Posted by SpectraCell Laboratories, Inc. on Wed, Feb 22, 2017 @ 02:25 PM

Young Woman_Old Woman.jpgEveryone knows that exercise is good for health: after all, it not only does the obvious (burns calories and builds strength), it furthermore helps balance hormones, lifts mood, and fights depression. Did you know that it also has a role in maintaining memory and cognitive function as we age?  A new study has shed light on yet another interesting way that exercise helps keep one young.  Researchers recently found that physical activity may help preserve telomeres, the strands of DNA at the end of chromosomes that protect genetic material from unraveling (like the plastic tips on the ends of shoelace). Each time a cell divides (a process that happens during cellular growth or repair), telomeres in that cell get a tiny bit shorter as DNA is lost, and shorter telomeres = faster aging. The cell is programmed to die when telomeres get too short. The cumulative effect of this process in cells throughout the body manifests as diseases of aging, and this is the reason for the preponderance of studies connecting telomere length with conditions such as diabetes, heart disease, cancer, arthritis, and other degenerative diseases. 

Fortunately, there are ways to protect these cellular “clocks.” Recent research suggests that a sedentary lifestyle is associated with shorter telomeres. In one study, scientists observed 1,481 older women (average age was 79 years old) and correlated telomere length with sedentary time. They found that among generally inactive women, the more sedentary the lifestyle, the shorter the telomeres (meaning they were aging faster). However - despite stretches of time engaged in sedentary activities (working at a desk, for example) - engaging in moderate-to-vigorous physical activity somewhat regularly appears to offer protection against shorter telomeres. In other words, 30 minutes of activity in a day despite inactivity most of the rest of the day (as in working at a computer or watching TV) did not contribute to cellular aging.  From a cellular standpoint, it truly does appear that a little exercise goes a long way.

Interested in knowing your true biological age? Find out with our Telomere Test
GET TESTED


 

Topics: telomere length, Telomere testing, Fountain of Youth, biological age, premature aging

Why Test YOUR Micronutrient Levels & MTHFR?

Posted by SpectraCell Laboratories, Inc. on Wed, Jul 10, 2013 @ 01:49 PM

New Grid 2013


Why is an MTHFR test important?

Determining your MTHFR genotype gives you valuable information about your body's ability to methylate.  Methylation is a crucial part of cell processes and reduced function has been linked to numerous medical conditions including neurological and cardiovascular disorders, mental dysfunctions and diabetes.  The old paradigm that we are simply at the mercy of our genes is now challenged by a new age of truly individualized healthcare.  Get vital knowledge for your personalized healthcare solutions today.

What role does nutrition play in this function?

Nutrition plays a substantial role in methylation pathways, and SpectraCell's Micronutrient testing can give you an accurate stats of 33 vitamins, minerals and amino acids.  You may be able to compensate for your body's inability to methylate efficiently through targeted repletion, and micronutrient testing will provide assessment of nutritional deficiencies.  The test also allows you to identify deficiencies in other micronutrients that can be contributing toward the development and/or progression of chronic disease and keep you from feeling your best.

SpectraCell Laboratories is combining the Micronutrient Testing and MTHFR Genotyping as a special package promotion.  To find out more CLICK HERE!

Topics: SpectraCell, micronutrients, micronutrient testing, Autoimmunity, cancer cells, autoimmune diseases, telomere length, Telomere testing, telomerase, B Vitamins, Antioxidants, Cardiovascular Health, MTHFR Genotyping, Genotyping, Heart Disease, vitamin, nutrition testing, supplements, Chronic Disease, diabetes, immune system, expecting mothers, early pregnancy, E-zinc, breast cancer, telomere, Elderly, Dr. Ron Grabowski, Minerals, micronutrient test, Nutritional Deficiency, Cancer Prevention, Heart Health, Gastrointestinal Tract, Hormones, telomere and cancer, Spectrox, Energy, Methylation, Estrogen, Immunidex, eczema and nutrition, Alzheimers, Free Radicals, Genetics, Dr. Eva Cwynar, Women's Health

Studies Show How Micronutrients can Help

Posted by SpectraCell Laboratories, Inc. on Thu, Apr 11, 2013 @ 03:04 PM

Vitamin D protects telomeres: a randomized, controlled trialTelomeres

Telomerase activity was measured before and after 37 people were given either placebo or about 2000IU of oral vitamin D supplements per day for 16 weeks.  Serum vitamin D levels for those taking the supplement increased almost 200%.  The telomerase activity increased over 19% as well, while the telomerase activity of those on placebo did not change. (International Journal of Obesity, June 2012)

LINK to ABSTRACT Increased telomerase activity and vitamin D supplementation in overweight African Americans.
LINK to FLYER ON NUTRIENT INTERACTIONS WITH TELOMERES

Vitamin C helps antidepressant drug work better
Vitamin C In this randomized, double-blind, placebo controlled trial, a group of patients with major depressive disorder (n=12) were given fluoxetine plus 1000mg of vitamin C daily and compared to a group (n=12) that were given fluoxetine plus placebo.  After six months, those receiving vitamin C in conjunction with fluoxetine showed a significant decrease in symptoms when evaluated using three different standardized depression rating systems compared to the placebo group. (Nutrition Journal, March 2013)

LINK to ABSTRACT Efficacy of vitamin C as an adjunct to fluoxetine therapy in pediatric major depressive disorder: a randomized, double-blind, placebo-controlled pilot study.
LINK to FREE FULL TEXT
LINK to FLYER ON NUTRIENT INTERACTIONS IN DEPRESSION

Serine improves ADHD symptoms
serine resized 600In this randomized, double-blind trial, 36 children diagnosed with ADHD received either 200mg of phosphatidylserine or placebo daily for two months.  Those receiving phosphatidylserine showed improved memory, attention and control of impulses compared to placebo.  Serine’s key role in psychiatric and neurological health has been gaining attention from studies such as this.  The authors concluded that phosphatidylserine “may be a safe and natural nutritional strategy for improving mental performance.”
(Journal of Human Nutrition and Dietetics, March 2013)

LINK to ABSTRACT The effect of phosphatidylserine administration on memory and symptoms of attention-deficit hyperactivity disorder: a randomised, double-blind, placebo-controlled clinical trial.
LINK to FLYER ON NUTRIENT INTERACTIONS IN ADHD

Are micronutrients underrated when it comes to pregnancy chances in assisted reproduction?
pregnancy resized 600Several recent studies are suggesting that micronutrient status prior to and during pregnancy should get more attention.  One study showed that low blood values of B vitamins and high homocysteine in mid pregnancy reduced fetal growth rates.  Another study showed that low homocysteine, determined by B vitamin status, was linked to a better chance of pregnancy in women undergoing assisted reproduction.  Yet another study showed that subfertile women undergoing ovulation induction who were taking a multi-micronutrient vitamin were more likely to get pregnant than women who took only a folic acid supplement.  Finally, a recently published review demonstrates how increasing a woman’s ability to fight oxidative stress increases her chances of successful pregnancy via assisted reproduction.
(Maternal of Child Nutrition, April 2013)
(Journal of Assisted Reproduction and Genetics, April 2012)
(Reproductive Biomedicine Online, January 2012)
(Reproductive Biology and Endocrinology, June 2012)

LINK to ABSTRACT Folate, Vitamin B12, Vitamin B6 and homocysteine: impact on pregnancy outcome.
LINK to ABSTRACT
The association between homocysteine in the follicular fluid with embryo quality and pregnancy rate in assisted reproductive techniques.
LINK to ABSTRACT Prospective randomized trial of multiple micronutrients in subfertile women undergoing ovulation induction: a pilot study.
LINK to ABSTRACT The effects of oxidative stress on female reproduction: a review.
LINK to FREE FULL TEXT
LINK to FLYER ON NUTRIENT INTERACTIONS IN FEMALE FERTILITY

Study sheds light on CoQ10’s role in healthy spermsperm resized 600
Sixty infertile men were given 200mg of CoQ10 or placebo for 3 months.  CoQ10 lowered oxidative stress in semen (measured by isoprostanes and superoxide dismutase activity) and improved sperm function significantly. (Andrologia, January 2013)

LINK to ABSTRACT Effect of Coenzyme Q10 supplementation on antioxidant enzymes activity and oxidative stress of seminal plasma: a double-blind randomised clinical trial.

 

For more information on micronutrients and telomeres CLICK HERE

 

Topics: SpectraCell, serine, micronutrients, Coenzyme Q10, Antidepressants, Vitamin D, Vitamin C, Telomere testing, telomere, deficiency, micronutrient test, ADHD, Nutritional Deficiency, Heart Health, Nutrient, telomere test, Hormones, Aging, Reproductive Health, infertility, Testosterone, Women's Health

Clinical Applications of MTHFR Genomic Testing

Posted by SpectraCell Laboratories, Inc. on Tue, Jan 22, 2013 @ 03:50 PM

Clinical Applications of MTHFR Genomic Testing webinar presented by Dr. Bridget Briggs
 
What you learned:  Dr. Briggs, MTHFR
  • Methylation processes in the body. 
  • The function of MTHFR and the common polymorphisms found in 40% of Americans
  • The links between the common polymorphisms in MTHFR and risks involving cardiovascular disease, thromboembolic disease, irritable bowel, depression, memory agility, autoimmunity, poor detoxification, infertility, PMS, insomnia and many other disorders. 
  • Treatment for patients with common polymorphisms including L-5 MTHF, Methylcobalamin, B6, Trimethylglycine, inositol, and other key nutrients.

  • Case Study Review

Clinical Applications of MTHFR Genomic Testing Webinar

 

Topics: SpectraCell, Autoimmunity, cancer cells, autoimmune diseases, Telomere testing, B Vitamins, Fibromyalgia, ApoE Genotyping, Cardiovascular Health, diagnostic tools, MTHFR Genotyping, Genotyping, Multivitamins, Chronic Disease, immune system, breast cancer, deficiencies, Elderly, chronic fatigue and nutrition, health, Case Study, Inflammatory Bowel Disease, degenerative illness, Cancer Prevention, Heart Health, Gastrointestinal Tract, cardiovascular disease, Energy, Methylation, Immunidex, Immunity, eczema and nutrition, Genetics, Bowel Disease, Controversy, Dr. Bridget Briggs, Women's Health

Success Story for Micronutrient & Telomere Testing

Posted by SpectraCell Laboratories, Inc. on Thu, Jun 21, 2012 @ 10:08 AM

Executive Medicine of TexasRecently, Dr. Walter Gaman of the Executive Medicine of Texas, recommended to a renowned supermodel, who recently overcame cancer, to start taking care of her body from the inside out.  He recommended some “cutting edge tests” within their Platinum Executive Physical which includes, “exams from micronutrient testing to telomere analysis which reveals your real age on a cellular level.”  

This is a great example of a physician and patient taking charge of their health by using SpectraCell's micronutrient and telomere testing.  She was very happy with her physical and, "…when [she] learned [she] had hypothyroidism and anemia and a few vitamin deficiencies, it was actually a relief to learn what was causing [her] to feel tired and to be able to address the issues and fix them. [She] now has homework to pump it up nutritionally and to implement changes in [her] physical level to achieve [her] personal best.”

Read the article here: “Supermodel Emme and Executive Medicine of Texas Join Forces to Urge Americans to Take Charge of their Health”


Topics: micronutrient testing, Cancer, Telomere testing, deficiencies

Archived Webinar: Managing the Aging Process

Posted by SpectraCell Laboratories, Inc. on Wed, May 23, 2012 @ 02:12 PM

Dr. Eva CwynarPresented by: Eva Cwynar, M.D.

Topics of Discussion:
  • Diagnostic tools and lifestyle changes for Age Management
  • How to maximize the body now to prevent fatigue and chronic disease
  • Revealing your cellular age – How to manage aging from the inside out
  • Testing for uncertainty – when a patient “just doesn’t feel right”
Click HERE to listen to the webinar and download the presentation slides

Topics: SpectraCell, Telomere testing, Chronic Disease, Aging

YEAR END SPECIAL!!! Micronutrient & Telomere Testing

Posted by SpectraCell Laboratories, Inc. on Mon, Nov 21, 2011 @ 02:42 PM

MNT & Telomere Testing resized 600Medicine now recognizes that every patient is biochemically unique, and this individuality extends to a patient's nutritional needs. In fact, a person's unique genetic blueprint will influence their nutritional needs and likewise, their nutritional status often influences gene expression. By measuring their comprehensive nutritional status with SpectraCell's micronutrient testing, deficiencies of 33 vitamins, minerals and antioxidants will be uncovered, thus allowing a targeted supplementation regimen based on the results. Correcting deficiencies can slow aging and degenerative disease progression, and the diagnostic epitome of cellular aging is telomere length. When combined with the innovative Telomere test, which tells your patient whether or not their biological age is older or younger than their chronological age, micronutrient testing is an exceptional tool that enables a physician to synergize this intimate interaction of genes and nutrition.

SpectraCell Laboratories, Inc. is combining their Micronutrient and Telomere Testing as an end of year special package with the Preferred Pay* pricing option.  Preferred Payment Options offer an upfront co-pay with no balance bill due to the patient. Pricing applies to all Preferred Pay Patients with approved insurance coverage. This offer is good through December 31, 2011. 

*Promotion is not applicable for Blue Cross Blue Shield patients drawn in AL, FL, IL, NC, NM, OK, SC, TX and Cigna patients. This promotion is not available for Medicare patients.

Contact your SpectraCell representative for details at  800-227-5227 or spec1@spectracell.com.


Topics: SpectraCell, micronutrient testing, Telomere testing, preferred payment option

SpectraCell's Telomere Testing Goes Mainstream

Posted by SpectraCell Laboratories, Inc. on Tue, Jul 26, 2011 @ 04:40 PM

Telomere TestingAmerica’s #1 rated morning news program, The Today Show, featured a story highlighting SpectraCell’s Telomere Test, a blood test that measures cellular aging. The segment entitled How to Live to 100 showcased SpectraCell’s Telomere Test as a tool for those interested in monitoring their health with biomarkers specific to longevity and aging. The Telomere Test measures a person’s biological age in comparison to their chronological age, giving a person an overall picture of how well they are aging.

SpectraCell was the first company to commercially offer telomere analysis to patients when it introduced its Telomere Test in June 2009. Before that, telomere testing was only available to researchers and university scientists. SpectraCell’s telomere testing was also recently featured in the New York Times (May 18, 2011). The Today Show, which has over five million viewers, aired the story on July 13, 2011. 

describe the imageTelomeres are sections of DNA at the end of chromosomes that cap genetic material and serve as protective buffers that prevent chromosomes from becoming attached to each other or rearranging. They are often compared to the caps at the ends of shoelaces. Every time a cell replicates, its telomere gets shorter, eventually causing cell death once the telomere attrition has reach its maximum. Measuring telomere length in human lymphocytes is an indicator of cellular aging, and research demonstrates that shortened telomeres are responsible for many of the normal processes of aging.

“SpectraCell Laboratories has always been on the cutting edge of diagnostic testing and Telomere Testing is no exception. We commercialized this test in direct response to interest from our physician clients, who saw it as a natural complement to our micronutrient testing,” says Otto Schaefer, Vice President of Sales and Marketing for SpectraCell. “The landscape of healthcare is really changing, with people taking charge of their own personal health information.”

The most common question asked by people who get the telomere test is “What do I do if I have a low telomere score?” Basic lifestyle changes are the first step – these include smoking cessation, moderate daily exercise and maintaining a healthy weight. For those who have already made these choices but still have a low telomere score, a comprehensive nutritional assessment is recommended.

Deficiencies in nutrients such as folate and vitamins C and D can shorten telomeres, so it is imperative to correct such deficiencies. Oxidative stress is another major culprit in telomere shortening so reducing inflammation and shoring up the body’s antioxidant defenses is critical for telomere maintenance. A person’s ability to combat free radicals, which cause oxidative stress, can be improved by correcting deficiencies in specific antioxidant nutrients, such as vitamin E, selenium and glutathione.

Telomere length is affected by many factors: age, genetics, lifestyle, disease and pharmaceuticals. Chronic diseases such as cardiovascular disease, hypertension, diabetes, obesity and dementia have strong associations with shorter telomeres. But telomere attrition can be mitigated significantly with aggressive lifestyle therapies as well as certain medications.

SpectraCell’s test measures a person’s telomere length. A control gene is also measured and compared to the telomere length, and then results are stated as a ratio. A higher ratio means a longer telomere, and younger biological age. The Telomere Score is also compared to other individuals in the same chronological age group.

This automated test is based on Quantitative Real Time PCR (polymerase chain reaction) technology and only requires 1 mL of whole blood. When a sample is received at SpectraCell’s Houston laboratory, the white blood cells are broken apart, the DNA is extracted and the telomeric DNA is amplified into a measurable signal. This signal is compared to a control gene of known length and a Telomere Score is generated. The price of the Telomere Test is $290. Testing once each year starting around age 25 is suggested to monitor the rate of telomere loss. More information at www.spectracell.com.

About SpectraCell Laboratories – SpectraCell is a CLIA accredited laboratory servicing healthcare providers nationwide by providing advanced clinical tests that measure nutritional status, cardiovascular risk, and cellular aging.

SpectraCell’s micronutrient tests measure the function of over 32 vitamins, minerals, amino acids and antioxidants in white blood cells, specifically taking into consideration personal differences in metabolism, age, genetics, health, prescription drug usage, absorption rate and other factors.

SpectraCell’s Telomere test measures how well a person’s body is aging internally. Many factors – both genetic and environmental – affect the rate of telomere loss, and this test provides an overall window into aging at the cellular level.

SpectraCell’s Lipoprotein Particle Profile™ is the most advanced lipoprotein particle test available, providing an accurate and in-depth assessment of cardiovascular risk.

Topics: SpectraCell, Telomere testing, telomere

NBC's TODAY Show Interviews SpectraCell

Posted by SpectraCell Laboratories, Inc. on Tue, Jul 12, 2011 @ 03:38 PM

The TODAY Show and SpectraCellNBC's The TODAY Show will air a segment on Aging and Telomere Testing tomorrow, Wednesday, July 13th between 8:00am - 9:00am EDT (7:00am - 8:00am CDT). Film crews were in Houston last week interviewing SpectraCell's clients and corporate personnel and filming our lab operations. Currently, SpectraCell is the only commercial lab offering this highly advanced diagnostic test in the United States.

Tune in tomorrow to catch a glimpse of our television interview. We highly anticipate a large influx of consumer website visitors from TODAY's 5 million+ viewers. We will be directing all patient inquiries for Telomere Testing to our Find-A-Clinician database listed on our homepage.

Topics: SpectraCell, telomere length, Telomere testing, The TODAY Show, NBC

"For a Longer & Better Life You Need to Know Your Score" by J. E. Block, M.D., F.A.C.P.

Posted by SpectraCell Laboratories, Inc. on Mon, May 23, 2011 @ 10:06 AM

J. E. Block, MD, FACP resized 600That score is your telomere count. Although many of us eat and maintain a healthy life style to look and feel better, there is a superior reason. That is to be BETTER and live LONGER. One can be productive and happy as a centurion (living 100+ years). How does one know how long and well they will live? Now there is a laboratory study for it, called TELOMERE TESTING. Until recently, the test was prohibitively expensive, but now for less than $400, one can obtain their report card and intervene on life style to get a better and better score to either achieve their goal or come very close to it. The Telomere test is a simple fasting or non-fasting blood test that can be carried out in most doctor’s office. For more information contact their Client Services Department (800-227-5227) or go online to www.SpectraCell.com.

Telomeres are sections of DNA at the end of each chromosome whose primary function is to prevent chromosomal “fraying” when a cell replicates. As a cell ages, its telomeres become shorter. How much shorter is governed by genetic factors and environmental stressors. Eventually, the telomeres become too short to allow cell replication, the cell stops dividing and will ultimately die which is a normal biological process. The more of our cells die, the older and frailer we become until we ourselves die. If our reserve is depleted, we succumb to disease or just old age. The Telomere Test can determine the length of your telomeres in relation to the chronological age. The Telomere Score is calculated based on the telomere length on white blood cells (T-lymphocytes). This is the average compared to telomere length on lymphocytes from a sample of the American population of the same age. The higher the telomere score, the “younger” the cells and the longer and better that person will live. Yearly, the test can be repeated and one can work harder or do other interventions that will enhance their score and their life.

Although we cannot change our genes we now can modify their expression by Lifestyle. In a study published in Nature this January scientists found the body activates a gene (P 53) that under stress shuts down our cells' normal growth and division cycle by controlling the telomere length. Diet plays a large role in this process. Micronutrients have been shown to have epigenetic effects by methylation of our DNA. The best but the most difficult is becoming a CRONI, (Caloric Restriction Optimal Nutritional Intake) to the point of just sustenance, a step away from starvation with just nutrient dense foods. Far easier and almost as good is eating correctly for your Apo E type, going easy on meat, with eating whole nutrient dense foods, as raw as possible, consumption of Omega 3s, and staying away from grains and processed foods. According to a study in the January 20, 2010 issue of JAMA, increased telomere and survival rates occurred among individuals with high dietary intake of marine omega-3 fatty acids and established cardiovascular disease. In this 5-year study, the researchers found that individuals with the lowest DHA+EPA experienced the most rapid rate of telomere shortening, whereas those in the highest had the slowest rate of shortening. Levels of DHA+EPA were associated with less telomere shortening before and after sequential adjustment for established risk factors and potential confounders. For each 1-standard deviation increase in red cell Omega 3 levels was associated with a 32 percent reduction in the odds of telomere shortening! Although both EPA and DHA are healthy, it seems that DHA is better. So consuming Tuna or Calamari Oil, which has a 4 to 1 ratio of DHA to EPA, is superior than any of the marine oils. What we eat and supplement today becomes the biology of our future.

Minimizing emotional (psychological) and physiological (infections, trauma and surgery) stress will keep your telomeres longer and you healthier. Additionally, increasing antioxidants slows telomere shortening. Physical exercise with adequate antioxidants will also give longer telomeres. Common sense dictates that decreasing cardiovascular risk factors (Lipids, Homocysteine, Blood Pressure, Hs-C Reactive Protein, Glucose etc.) and correcting micronutrient deficencies such as Vitamins, Minerals, and Glutathione will preserve the telomere length. Periodically getting rid of our poison buildup by colonic, and liver cleanses and from the skin by sweating (artificially by sauna or by heavy exercise) and minimizing the toxins in our water, air and food will go a long way in keeping our telomeres longer. Keeping our hormones (Thyroid, Sex and Adrenal hormones) in balance and not getting sick also keeps our telomeres longer. To not get sick means keeping our immune system healthy to include the consumption of Pre and Probiotics. Surgery should be only for life saving problems and not for elective procedures since the operation and the anesthesia shortens the telomeres. Staying out of harms' way for bodily damage in our daily pursuits such as not over indulging in alcohol and dangerous sports and occupations will keep our telomeres and our lives longer.

Although it is far better to live a healthy life style, there are drugs that also have been shown to decrease our telomere shortening. The antihypertensives, Angiotension Converting Enzyme drugs such as Lisinopril and the Angiotension Recepter Blockers like Lorsartan have been shown to extend our telomeres. Likewise so has the Cholesterol lowering Statins. These drugs should be used judiciously, not to lower our lipids too much and to take concomitantly CoEnzyme Q 10. Also the diabetic medicine, Metformin, has been shown to be antiaging. But with this drug many physicians recommend using B12 too. Age is how old we are, but old is what our body is biologically. In reality it is not how old you are, but how you are when you are old that counts!

Written by J. E. Block, MD, FACP

Doc Block's Blog

docblocksblog.blogspot.com

Topics: SpectraCell, telomere length, Telomere testing, telomerase, telomere, Longevity